product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PE/Cyanine7 anti-human CD184 (CXCR4)
catalog :
306514
quantity :
100 tests
price :
323 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE/Cy7
clone name :
12G5
reactivity :
human, rhesus macaque
application :
flow cytometry
more info or order :
citations: 18
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 3e, e4k
Dr xe4 ger N, Sattler S, Huang C, Teter O, Leng K, Hashemi S, et al. A CRISPRi/a platform in human iPSC-derived microglia uncovers regulators of disease states. Nat Neurosci. 2022;25:1149-1162 pubmed publisher
  • flow cytometry; human
Bendall S, Simonds E, Qiu P, Amir E, Krutzik P, Finck R, et al. Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. Science. 2011;332:687-96 pubmed publisher
Kielbassa K, Haselager M, Bax D, van Driel B, Dubois J, Levin M, et al. Ibrutinib sensitizes CLL cells to venetoclax by interrupting TLR9-induced CD40 upregulation and protein translation. Leukemia. 2023;37:1268-1276 pubmed publisher
Felker S, Shrestha A, Bailey J, Pillis D, Siniard D, Malik P. Differential CXCR4 expression on hematopoietic progenitor cells versus stem cells directs homing and engraftment. JCI Insight. 2022;7: pubmed publisher
Albanese M, Ruhle A, Mittermaier J, Mejías Pérez E, Gapp M, Linder A, et al. Rapid, efficient and activation-neutral gene editing of polyclonal primary human resting CD4+ T cells allows complex functional analyses. Nat Methods. 2022;19:81-89 pubmed publisher
Li Y, Zhou Y, Kim Y, Zhu Y, Ma F, Yu J, et al. Development of allogeneic HSC-engineered iNKT cells for off-the-shelf cancer immunotherapy. Cell Rep Med. 2021;2:100449 pubmed publisher
Rodriguez A, Zhang K, Färkkilä A, Filiatrault J, Yang C, Velázquez M, et al. MYC Promotes Bone Marrow Stem Cell Dysfunction in Fanconi Anemia. Cell Stem Cell. 2021;28:33-47.e8 pubmed publisher
Zhu Y, Smith D, Zhou Y, Li Y, Yu J, Lee D, et al. Development of Hematopoietic Stem Cell-Engineered Invariant Natural Killer T Cell Therapy for Cancer. Cell Stem Cell. 2019;25:542-557.e9 pubmed publisher
Howden S, Hosseini Far H, Motazedian A, Elefanty A, Stanley E, Lamande S, et al. The use of simultaneous reprogramming and gene correction to generate an osteogenesis imperfecta patient COL1A1 c. 3936 G>T iPSC line and an isogenic control iPSC line. Stem Cell Res. 2019;38:101453 pubmed publisher
Hosseini Far H, Patria Y, Motazedian A, Elefanty A, Stanley E, Lamande S, et al. Generation of a heterozygous COL1A1 (c.3969_3970insT) osteogenesis imperfecta mutation human iPSC line, MCRIi001-A-1, using CRISPR/Cas9 editing. Stem Cell Res. 2019;37:101449 pubmed publisher
Vlahos K, Sourris K, Mayberry R, McDonald P, Bruveris F, Schiesser J, et al. Generation of iPSC lines from peripheral blood mononuclear cells from 5 healthy adults. Stem Cell Res. 2019;34:101380 pubmed publisher
Velázquez Avila M, Balandrán J, Ramírez Ramírez D, Velázquez Avila M, Sandoval A, Felipe López A, et al. High cortactin expression in B-cell acute lymphoblastic leukemia is associated with increased transendothelial migration and bone marrow relapse. Leukemia. 2019;33:1337-1348 pubmed publisher
Smith N, Vidalain P, Nisole S, Herbeuval J. An efficient method for gene silencing in human primary plasmacytoid dendritic cells: silencing of the TLR7/IRF-7 pathway as a proof of concept. Sci Rep. 2016;6:29891 pubmed publisher
Lourenço S, Teixeira V, Kalber T, José R, Floto R, Janes S. Macrophage migration inhibitory factor-CXCR4 is the dominant chemotactic axis in human mesenchymal stem cell recruitment to tumors. J Immunol. 2015;194:3463-74 pubmed publisher
Martínez Cingolani C, Grandclaudon M, Jeanmougin M, Jouve M, Zollinger R, Soumelis V. Human blood BDCA-1 dendritic cells differentiate into Langerhans-like cells with thymic stromal lymphopoietin and TGF-β. Blood. 2014;124:2411-20 pubmed publisher
Raposo R, Abdel Mohsen M, Holditch S, Kuebler P, Cheng R, Eriksson E, et al. Increased expression of intrinsic antiviral genes in HLA-B*57-positive individuals. J Leukoc Biol. 2013;94:1051-9 pubmed publisher
Isnardi I, Ng Y, Menard L, Meyers G, Saadoun D, Srdanovic I, et al. Complement receptor 2/CD21- human naive B cells contain mostly autoreactive unresponsive clones. Blood. 2010;115:5026-36 pubmed publisher
Thompson B, Jin Y, Wu K, Colvin R, Luster A, Birnbaumer L, et al. Inhibition of G alpha i2 activation by G alpha i3 in CXCR3-mediated signaling. J Biol Chem. 2007;282:9547-55 pubmed
product information
Antigen :
CD184
Apps. Abbrev. :
FC
Cat # :
306514
Clone :
12G5
Item :
PE/Cyanine7 anti-human CD184 (CXCR4)
Isotype :
Mouse IgG2a, κ
Other Names :
CXCR4, Fusin
Size :
100 tests
Price (USD) :
323 USD
Reactivity :
Human, Cynomolgus, Rhesus
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PE_CYANINE7
Immunogen :
CP-MAC-infected Sup-T1 cells
Application Notes :
Additional reported applications (for the relevant formats) include: immunohistochemical staining of paraffin-embedded tissue sections^11, immunocytochemistry^3, immunofluorescence microscopy^2,6, and blocking of CD4-independent infection by HIV-2 and CD4-dependent infection by some T cell-tropic isolates of HIV-1^4,5. Clone 12G5 may not be suitable for Western blotting.^10 The Ultra-LEAF™ purified antibody (Endotoxin <0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. Nos. 306539 & 306540).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA