LEAF™ Purified anti-human CD184 (CXCR4) | BioLegend 306512 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

LEAF™ Purified anti-human CD184 (CXCR4)

catalog :

306512

quantity :

500 ug

price :

330 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

12G5

reactivity :

human, chimpanzee, rhesus macaque

application :

immunohistochemistry, immunocytochemistry, neutralization, flow cytometry

citations: 5

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig st1	Cerboni S, Jeremiah N, Gentili M, Gehrmann U, Conrad C, Stolzenberg M, et al. Intrinsic antiproliferative activity of the innate sensor STING in T lymphocytes. J Exp Med. 2017;214:1769-1785 pubmed publisher
flow cytometry; human; 1:100; loading ...; fig s4b immunocytochemistry; human; 1:50; loading ...; fig s3a	Smith N, Pietrancosta N, Davidson S, Dutrieux J, Chauveau L, Cutolo P, et al. Natural amines inhibit activation of human plasmacytoid dendritic cells through CXCR4 engagement. Nat Commun. 2017;8:14253 pubmed publisher
flow cytometry; human; loading ...; fig 3a	Gadd V, Patel P, Jose S, Horsfall L, Powell E, Irvine K. Altered Peripheral Blood Monocyte Phenotype and Function in Chronic Liver Disease: Implications for Hepatic Recruitment and Systemic Inflammation. PLoS ONE. 2016;11:e0157771 pubmed publisher
flow cytometry; human	Bendall S, Simonds E, Qiu P, Amir E, Krutzik P, Finck R, et al. Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. Science. 2011;332:687-96 pubmed publisher
	Chittasupho C, Anuchapreeda S, Sarisuta N. CXCR4 targeted dendrimer for anti-cancer drug delivery and breast cancer cell migration inhibition. Eur J Pharm Biopharm. 2017;119:310-321 pubmed publisher

product information

Antigen :

CD184

Apps. Abbrev. :

Flow Cytometry, Immunofluorescence Microscopy, CyTOF®, Block, ICC, IHC

Cat # :

306512

Clone :

12G5

Item :

LEAF™ Purified anti-human CD184 (CXCR4)

Isotype :

Mouse IgG2a, kappa

Other Names :

CXCR4, Fusin

Size :

500 ug

Price (USD) :

330 USD

Reactivity :

Human, African Green, Baboon, Chimpanzee, Cynomolgus, Rhesus, Sooty Mangabey

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

LEAF

Immunogen :

CP-MAC-infected Sup-T1 cells

Application Notes :

. Additional reported applications (for the relevant formats) include: immunohistochemical staining of paraffin-embedded tissue sections 11 , immunocytochemistry 3 , immunofluorescence microscopy 2,6 , and blocking of CD4-independent infection by HIV-2 and CD4-dependent infection by some T cell-tropic isolates of HIV-1 4,5 . Clone 12G5 may not be suitable for Western blotting. 10 The Ultra-LEAF™ purified antibody (Endotoxin 0.01 EU/ug, Azide-Free, 0.2 um filtered) is recommended for functional assays (Cat. Nos. 306539 306540).