product summary
Loading...
company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
APC anti-human CD184 (CXCR4)
catalog :
306509
quantity :
25 tests
price :
154 USD
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
12G5
reactivity :
human, rhesus macaque
application :
flow cytometry
more info or order :
citations: 31
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; 2 ug/ml; fig 5b
Kamiyama D, Sekine S, Barsi Rhyne B, Hu J, Chen B, Gilbert L, et al. Versatile protein tagging in cells with split fluorescent protein. Nat Commun. 2016;7:11046 pubmed publisher
  • flow cytometry; human
Bendall S, Simonds E, Qiu P, Amir E, Krutzik P, Finck R, et al. Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. Science. 2011;332:687-96 pubmed publisher
Roukens A, Pothast C, König M, Huisman W, Dalebout T, Tak T, et al. Prolonged activation of nasal immune cell populations and development of tissue-resident SARS-CoV-2-specific CD8+ T cell responses following COVID-19. Nat Immunol. 2022;23:23-32 pubmed publisher
Beatson R, Parente Pereira A, Halim L, Cozzetto D, Hull C, Whilding L, et al. TGF-β1 potentiates Vγ9Vδ2 T cell adoptive immunotherapy of cancer. Cell Rep Med. 2021;2:100473 pubmed publisher
Olety B, Peters P, Wu Y, Usami Y, Gottlinger H. HIV-1 propagation is highly dependent on basal levels of the restriction factor BST2. Sci Adv. 2021;7:eabj7398 pubmed publisher
Xu X, Chemparathy A, Zeng L, Kempton H, Shang S, Nakamura M, et al. Engineered miniature CRISPR-Cas system for mammalian genome regulation and editing. Mol Cell. 2021;81:4333-4345.e4 pubmed publisher
Cai J, Gao H, Zhao J, Hu S, Liang X, Yang Y, et al. Infection with a newly designed dual fluorescent reporter HIV-1 effectively identifies latently infected CD4+ T cells. elife. 2021;10: pubmed publisher
Lu P, Wang S, Franzen C, Venkataraman G, McClure R, Li L, et al. Ibrutinib and venetoclax target distinct subpopulations of CLL cells: implication for residual disease eradication. Blood Cancer J. 2021;11:39 pubmed publisher
Samuel R, Majd H, Richter M, Ghazizadeh Z, Zekavat S, Navickas A, et al. Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men. Cell Stem Cell. 2020;27:876-889.e12 pubmed publisher
Rai M, Hammonds J, Pujato M, Mayhew C, Roskin K, Spearman P. Comparative analysis of human microglial models for studies of HIV replication and pathogenesis. Retrovirology. 2020;17:35 pubmed publisher
Gludish D, Boliar S, Caldwell S, Tembo D, Chimbayo E, Jambo K, et al. TZM-gfp cells: a tractable fluorescent tool for analysis of rare and early HIV-1 infection. Sci Rep. 2020;10:19900 pubmed publisher
Biasci D, Smoragiewicz M, Connell C, Wang Z, Gao Y, Thaventhiran J, et al. CXCR4 inhibition in human pancreatic and colorectal cancers induces an integrated immune response. Proc Natl Acad Sci U S A. 2020;117:28960-28970 pubmed publisher
McQuade A, Kang Y, Hasselmann J, Jairaman A, Sotelo A, Coburn M, et al. Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer's disease. Nat Commun. 2020;11:5370 pubmed publisher
Agha O, Mueller Immergluck A, Liu M, Zhang H, Theologis A, Clark A, et al. Intervertebral disc herniation effects on multifidus muscle composition and resident stem cell populations. JOR Spine. 2020;3:e1091 pubmed publisher
Bourges C, Groff A, Burren O, Gerhardinger C, Mattioli K, Hutchinson A, et al. Resolving mechanisms of immune-mediated disease in primary CD4 T cells. EMBO Mol Med. 2020;12:e12112 pubmed publisher
Fiedorowicz M, Khan M, Strzemecki D, Orzeł J, Wełniak Kamińska M, Sobiborowicz A, et al. Renal carcinoma CD105-/CD44- cells display stem-like properties in vitro and form aggressive tumors in vivo. Sci Rep. 2020;10:5379 pubmed publisher
Foight G, Wang Z, Wei C, Jr Greisen P, Warner K, Cunningham Bryant D, et al. Multi-input chemical control of protein dimerization for programming graded cellular responses. Nat Biotechnol. 2019;37:1209-1216 pubmed publisher
Roco J, Mesin L, Binder S, Nefzger C, Gonzalez Figueroa P, Canete P, et al. Class-Switch Recombination Occurs Infrequently in Germinal Centers. Immunity. 2019;51:337-350.e7 pubmed publisher
Nakamura M, Srinivasan P, Chavez M, Carter M, Dominguez A, La Russa M, et al. Anti-CRISPR-mediated control of gene editing and synthetic circuits in eukaryotic cells. Nat Commun. 2019;10:194 pubmed publisher
Zhang Y, Yang Y, Jiang M, Huang S, Zhang W, Al Alam D, et al. 3D Modeling of Esophageal Development using Human PSC-Derived Basal Progenitors Reveals a Critical Role for Notch Signaling. Cell Stem Cell. 2018;23:516-529.e5 pubmed publisher
Meng Y, Liang J, Wu C, Xu J, Zeng D, Yu X, et al. Monocytes/Macrophages promote vascular CXCR4 expression via the ERK pathway in hepatocellular carcinoma. Oncoimmunology. 2018;7:e1408745 pubmed publisher
Taguchi A, Nishinakamura R. Higher-Order Kidney Organogenesis from Pluripotent Stem Cells. Cell Stem Cell. 2017;21:730-746.e6 pubmed publisher
Shan L, Deng K, Gao H, Xing S, Capoferri A, Durand C, et al. Transcriptional Reprogramming during Effector-to-Memory Transition Renders CD4+ T Cells Permissive for Latent HIV-1 Infection. Immunity. 2017;47:766-775.e3 pubmed publisher
Lee H, Bellat V, Law B. Chemotherapy induces adaptive drug resistance and metastatic potentials via phenotypic CXCR4-expressing cell state transition in ovarian cancer. PLoS ONE. 2017;12:e0171044 pubmed publisher
Gao Y, Xiong X, Wong S, Charles E, Lim W, Qi L. Complex transcriptional modulation with orthogonal and inducible dCas9 regulators. Nat Methods. 2016;13:1043-1049 pubmed publisher
Ogaki S, Morooka M, Otera K, Kume S. A cost-effective system for differentiation of intestinal epithelium from human induced pluripotent stem cells. Sci Rep. 2015;5:17297 pubmed publisher
Wostradowski T, Gudi V, Pul R, Gingele S, Lindquist J, Stangel M, et al. Effect of interferon-β1b on CXCR4-dependent chemotaxis in T cells from multiple sclerosis patients. Clin Exp Immunol. 2015;182:162-72 pubmed publisher
Toyoda M, Ogata Y, Mahiti M, Maeda Y, Kuang X, Miura T, et al. Differential Ability of Primary HIV-1 Nef Isolates To Downregulate HIV-1 Entry Receptors. J Virol. 2015;89:9639-52 pubmed publisher
Huijbregts R, Helton E, Michel K, Sabbaj S, Richter H, Goepfert P, et al. Hormonal contraception and HIV-1 infection: medroxyprogesterone acetate suppresses innate and adaptive immune mechanisms. Endocrinology. 2013;154:1282-95 pubmed publisher
Shi J, Ge M, Lu S, Li X, Shao Y, Huang J, et al. Intrinsic impairment of CD4(+)CD25(+) regulatory T cells in acquired aplastic anemia. Blood. 2012;120:1624-32 pubmed publisher
Isnardi I, Ng Y, Menard L, Meyers G, Saadoun D, Srdanovic I, et al. Complement receptor 2/CD21- human naive B cells contain mostly autoreactive unresponsive clones. Blood. 2010;115:5026-36 pubmed publisher
product information
Antigen :
CD184
Apps. Abbrev. :
FC
Cat # :
306509
Clone :
12G5
Item :
APC anti-human CD184 (CXCR4)
Isotype :
Mouse IgG2a, κ
Other Names :
CXCR4, Fusin
Size :
25 tests
Price (USD) :
154 USD
Reactivity :
Human, Cynomolgus, Rhesus
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
APC
Immunogen :
CP-MAC-infected Sup-T1 cells
Application Notes :
Additional reported applications (for the relevant formats) include: immunohistochemical staining of paraffin-embedded tissue sections^11, immunocytochemistry^3, immunofluorescence microscopy^2,6, and blocking of CD4-independent infection by HIV-2 and CD4-dependent infection by some T cell-tropic isolates of HIV-1^4,5. Clone 12G5 may not be suitable for Western blotting.^10 The Ultra-LEAF™ purified antibody (Endotoxin <0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. Nos. 306539 & 306540).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA