product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
APC anti-human CD123
catalog :
306011
quantity :
25 tests
price :
123 USD
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
6H6
reactivity :
human
application :
flow cytometry
more info or order :
citations: 21
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human
Jitschin R, Braun M, Büttner M, Dettmer Wilde K, Bricks J, Berger J, et al. CLL-cells induce IDOhi CD14+HLA-DRlo myeloid-derived suppressor cells that inhibit T-cell responses and promote TRegs. Blood. 2014;124:750-60 pubmed publisher
Zhang X, Zheng B, Zhao L, Shen J, Yang Z, Zhang Y, et al. KLF4-PFKFB3-driven glycolysis is essential for phenotypic switching of vascular smooth muscle cells. Commun Biol. 2022;5:1332 pubmed publisher
Kitai H, Kato N, Ogami K, Komatsu S, Watanabe Y, Yoshino S, et al. Systematic characterization of seed overlap microRNA cotargeting associated with lupus pathogenesis. BMC Biol. 2022;20:248 pubmed publisher
Vijayakumar B, Boustani K, Ogger P, Papadaki A, Tonkin J, Orton C, et al. Immuno-proteomic profiling reveals aberrant immune cell regulation in the airways of individuals with ongoing post-COVID-19 respiratory disease. Immunity. 2022;55:542-556.e5 pubmed publisher
Ugawa M, Kawamura Y, Toda K, Teranishi K, Morita H, Adachi H, et al. In silico-labeled ghost cytometry. elife. 2021;10: pubmed publisher
Lu J, Sun K, Yang H, Fan D, Huang H, Hong Y, et al. Sepsis Inflammation Impairs the Generation of Functional Dendritic Cells by Targeting Their Progenitors. Front Immunol. 2021;12:732612 pubmed publisher
Georgakis S, Gkirtzimanaki K, Papadaki G, Gakiopoulou H, Drakos E, Eloranta M, et al. NETs decorated with bioactive IL-33 infiltrate inflamed tissues and induce IFN-α production in patients with SLE. JCI Insight. 2021;6: pubmed publisher
Thompson E, Cascino K, Ordonez A, Zhou W, Vaghasia A, Hamacher Brady A, et al. Metabolic programs define dysfunctional immune responses in severe COVID-19 patients. Cell Rep. 2021;34:108863 pubmed publisher
González Tajuelo R, González Sánchez E, Silván J, Muñoz Callejas A, Vicente Rabaneda E, Garcia Perez J, et al. Relevance of PSGL-1 Expression in B Cell Development and Activation. Front Immunol. 2020;11:588212 pubmed publisher
Oliveira J, Gandini M, Sales J, Fujimori S, Barbosa M, Frutuoso V, et al. Mycobacterium leprae induces a tolerogenic profile in monocyte-derived dendritic cells via TLR2 induction of IDO. J Leukoc Biol. 2021;110:167-176 pubmed publisher
Shevchenko J, Khristin A, Kurilin V, Kuznetsova M, Blinova D, Starostina N, et al. Autologous dendritic cells and activated cytotoxic T‑cells as combination therapy for breast cancer. Oncol Rep. 2020;43:671-680 pubmed publisher
Kubota S, Tokunaga K, Umezu T, Yokomizo Nakano T, Sun Y, Oshima M, et al. Lineage-specific RUNX2 super-enhancer activates MYC and promotes the development of blastic plasmacytoid dendritic cell neoplasm. Nat Commun. 2019;10:1653 pubmed publisher
Bi E, Li R, Bover L, Li H, Su P, Ma X, et al. E-cadherin expression on multiple myeloma cells activates tumor-promoting properties in plasmacytoid DCs. J Clin Invest. 2018;128:4821-4831 pubmed publisher
Halim T, Rana B, Walker J, Kerscher B, Knolle M, Jolin H, et al. Tissue-Restricted Adaptive Type 2 Immunity Is Orchestrated by Expression of the Costimulatory Molecule OX40L on Group 2 Innate Lymphoid Cells. Immunity. 2018;48:1195-1207.e6 pubmed publisher
Conrad C, Di Domizio J, Mylonas A, Belkhodja C, Demaria O, Navarini A, et al. TNF blockade induces a dysregulated type I interferon response without autoimmunity in paradoxical psoriasis. Nat Commun. 2018;9:25 pubmed publisher
Pierog P, Zhao Y, Singh S, Dai J, Yap G, Fitzgerald Bocarsly P. Toxoplasma gondii Inactivates Human Plasmacytoid Dendritic Cells by Functional Mimicry of IL-10. J Immunol. 2018;200:186-195 pubmed publisher
Macal M, Tam M, Hesser C, Di Domizio J, Léger P, Gilliet M, et al. CD28 Deficiency Enhances Type I IFN Production by Murine Plasmacytoid Dendritic Cells. J Immunol. 2016;196:1900-9 pubmed publisher
Dai Y, Chen S, Kmieciak M, Zhou L, Lin H, Pei X, et al. The novel Chk1 inhibitor MK-8776 sensitizes human leukemia cells to HDAC inhibitors by targeting the intra-S checkpoint and DNA replication and repair. Mol Cancer Ther. 2013;12:878-89 pubmed publisher
Labidi Galy S, Sisirak V, Meeus P, Gobert M, Treilleux I, Bajard A, et al. Quantitative and functional alterations of plasmacytoid dendritic cells contribute to immune tolerance in ovarian cancer. Cancer Res. 2011;71:5423-34 pubmed publisher
Charles N, Hardwick D, Daugas E, Illei G, Rivera J. Basophils and the T helper 2 environment can promote the development of lupus nephritis. Nat Med. 2010;16:701-7 pubmed publisher
Martin Gayo E, Sierra Filardi E, Corbi A, Toribio M. Plasmacytoid dendritic cells resident in human thymus drive natural Treg cell development. Blood. 2010;115:5366-75 pubmed publisher
product information
Antigen :
CD123
Apps. Abbrev. :
FC
Cat # :
306011
Clone :
6H6
Item :
APC anti-human CD123
Isotype :
Mouse IgG1, κ
Other Names :
IL-3Rα, IL-3 Receptor alpha
Size :
25 tests
Price (USD) :
123 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
APC
Immunogen :
Human IL-3Rα transfected COS cells.
Application Notes :
Clone 6H6 does not inhibit IL-3 binding to low- or high-affinity IL-3Rs. Additional reported applications (for the relevant formats) include: Western blotting^1, immunoprecipitation^1, and immunohistochemical staining of acetone-fixed frozen sections^2 and also paraformaldehyde fixed paraffin embedded tissue^7.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA