TotalSeq™-A0156 anti-human CD95 (Fas) | BioLegend 305649 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

TotalSeq™-A0156 anti-human CD95 (Fas)

catalog :

305649

quantity :

10 μg

price :

369 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

DX2

reactivity :

human, rhesus macaque

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 8

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig 2b	Zhu Y, Xie J, Shi J. Rac1/ROCK-driven membrane dynamics promote natural killer cell cytotoxicity via granzyme-induced necroptosis. BMC Biol. 2021;19:140 pubmed publisher
flow cytometry; human; loading ...; fig e4d	Lynn R, Weber E, Sotillo E, Gennert D, Xu P, Good Z, et al. c-Jun overexpression in CAR T cells induces exhaustion resistance. Nature. 2019;576:293-300 pubmed publisher
flow cytometry; human; loading ...; fig 3f, 3g	Fransen N, Crusius J, Smolders J, Mizee M, Van Eden C, Luchetti S, et al. Post-mortem multiple sclerosis lesion pathology is influenced by single nucleotide polymorphisms. Brain Pathol. 2020;30:106-119 pubmed publisher
flow cytometry; rhesus macaque; loading ...; fig 3a	Hoang T, Harper J, Pino M, Wang H, Micci L, King C, et al. Bone Marrow-Derived CD4+ T Cells Are Depleted in Simian Immunodeficiency Virus-Infected Macaques and Contribute to the Size of the Replication-Competent Reservoir. J Virol. 2019;93: pubmed publisher
	Gomez Collignon A, Brown R, Carr A, Dakin S, Lach A, Loizou C, et al. Single cell multi-omics characterise discrete human tendon cells populations that persist in vitro and on fibrous scaffolds. Eur Cell Mater. 2022;44:1-20 pubmed publisher
	Hao Y, Hao S, Andersen Nissen E, Mauck W, Zheng S, Butler A, et al. Integrated analysis of multimodal single-cell data. Cell. 2021;184:3573-3587.e29 pubmed publisher
	Swanson E, Lord C, Reading J, Heubeck A, Genge P, Thomson Z, et al. Simultaneous trimodal single-cell measurement of transcripts, epitopes, and chromatin accessibility using TEA-seq. elife. 2021;10: pubmed publisher
	Wirka R, Wagh D, Paik D, Pjanic M, Nguyen T, Miller C, et al. Atheroprotective roles of smooth muscle cell phenotypic modulation and the TCF21 disease gene as revealed by single-cell analysis. Nat Med. 2019;25:1280-1289 pubmed publisher

product information

Antigen :

CD95

Apps. Abbrev. :

Cat # :

305649

Clone :

DX2

Item :

TotalSeq™-A0156 anti-human CD95 (Fas)

Isotype :

Mouse IgG1, κ

Other Names :

Fas, APO-1, TNFRSF6

Size :

10 μg

Price (USD) :

369 USD

Reactivity :

Human, Cynomolgus, Rhesus

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

TOTALSEQ_A

Immunogen :

CD95 transfected L cells

Application Notes :

The DX2 antibody is useful for inducing apoptosis of Fas-positive cells. Additional reported applications (for the relevant formats) include: in vitro induction of apoptosis^3 (DX2 antibody is required to be cross-linked for effective induction of apoptosis) and immunohistochemical staining^4,5 of acetone-fixed frozen tissue sections and formalin-fixed paraffin-embedded tissue sections. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 305655 and 305656).Note: EOS9.1 antibody can induce apoptosis without cross-linking.;

more info or order :

BioLegend product webpage