product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Brilliant Violet 711™ anti-human CD95 (Fas)
catalog :
305643
quantity :
25 tests
price :
215 USD
clonality :
monoclonal
host :
mouse
conjugate :
BV711
clone name :
DX2
reactivity :
human, rhesus macaque
application :
flow cytometry
more info or order :
citations: 5
Reference
Preglej T, Brinkmann M, Steiner G, Aletaha D, G xf6 schl L, Bonelli M. Advanced immunophenotyping: A powerful tool for immune profiling, drug screening, and a personalized treatment approach. Front Immunol. 2023;14:1096096 pubmed publisher
Kramer B, Knoll R, Bonaguro L, ToVinh M, Raabe J, Astaburuaga García R, et al. Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19. Immunity. 2021;54:2650-2669.e14 pubmed publisher
He X, Chandrashekar A, Zahn R, Wegmann F, Yu J, Mercado N, et al. Low-dose Ad26.COV2.S protection against SARS-CoV-2 challenge in rhesus macaques. Cell. 2021;184:3467-3473.e11 pubmed publisher
Kuri Cervantes L, Pampena M, Betts M. Phenotypic Characterization of SLex+ and CLA+ CD4+ T Cells. STAR Protoc. 2020;1:100154 pubmed publisher
Huang X, Williams J, Chang R, Li Z, Burnett C, Hernández López R, et al. DNA scaffolds enable efficient and tunable functionalization of biomaterials for immune cell modulation. Nat Nanotechnol. 2021;16:214-223 pubmed publisher
product information
Antigen :
CD95
Apps. Abbrev. :
FC
Cat # :
305643
Clone :
DX2
Item :
Brilliant Violet 711™ anti-human CD95 (Fas)
Isotype :
Mouse IgG1, κ
Other Names :
Fas, APO-1, TNFRSF6
Size :
25 tests
Price (USD) :
215 USD
Reactivity :
Human, Cynomolgus, Rhesus
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
BV711
Immunogen :
CD95 transfected L cells
Application Notes :
The DX2 antibody is useful for inducing apoptosis of Fas-positive cells. Additional reported applications (for the relevant formats) include: in vitro induction of apoptosis^3 (DX2 antibody is required to be cross-linked for effective induction of apoptosis) and immunohistochemical staining^4,5 of acetone-fixed frozen tissue sections and formalin-fixed paraffin-embedded tissue sections. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 305655 and 305656).Note: EOS9.1 antibody can induce apoptosis without cross-linking.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA