product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PerCP/Cyanine5.5 anti-human CD95 (Fas)
catalog :
305629
quantity :
25 tests
price :
147 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
DX2
reactivity :
human, rhesus macaque
application :
flow cytometry
more info or order :
citations: 3
Reference
Alsalloum A, Alrhmoun S, Perik Zavosdkaia O, Fisher M, Volynets M, Lopatnikova J, et al. Decoding NY-ESO-1 TCR T cells: transcriptomic insights reveal dual mechanisms of tumor targeting in a melanoma murine xenograft model. Front Immunol. 2024;15:1507218 pubmed publisher
Das S, Valton J, Duchateau P, Poirot L. Stromal depletion by TALEN-edited universal hypoimmunogenic FAP-CAR T cells enables infiltration and anti-tumor cytotoxicity of tumor antigen-targeted CAR-T immunotherapy. Front Immunol. 2023;14:1172681 pubmed publisher
Caeser R, Di Re M, Krupka J, Gao J, Lara Chica M, Dias J, et al. Genetic modification of primary human B cells to model high-grade lymphoma. Nat Commun. 2019;10:4543 pubmed publisher
product information
Antigen :
CD95
Apps. Abbrev. :
FC
Cat # :
305629
Clone :
DX2
Item :
PerCP/Cyanine5.5 anti-human CD95 (Fas)
Isotype :
Mouse IgG1, κ
Other Names :
Fas, APO-1, TNFRSF6
Size :
25 tests
Price (USD) :
147 USD
Reactivity :
Human, Cynomolgus, Rhesus
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PERCP_CYANINE5.5
Immunogen :
CD95 transfected L cells
Application Notes :
The DX2 antibody is useful for inducing apoptosis of Fas-positive cells. Additional reported applications (for the relevant formats) include: in vitro induction of apoptosis^3 (DX2 antibody is required to be cross-linked for effective induction of apoptosis) and immunohistochemical staining^4,5 of acetone-fixed frozen tissue sections and formalin-fixed paraffin-embedded tissue sections. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 305655 and 305656).Note: EOS9.1 antibody can induce apoptosis without cross-linking.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA