product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Brilliant Violet 605™ anti-human CD95 (Fas)
catalog :
305628
quantity :
100 tests
price :
435 USD
clonality :
monoclonal
host :
mouse
conjugate :
BV605
clone name :
DX2
reactivity :
human, rhesus macaque
application :
flow cytometry
more info or order :
citations: 16
Published Application/Species/Sample/DilutionReference
  • flow cytometry; rhesus macaque; loading ...; fig 3a
Hoang T, Harper J, Pino M, Wang H, Micci L, King C, et al. Bone Marrow-Derived CD4+ T Cells Are Depleted in Simian Immunodeficiency Virus-Infected Macaques and Contribute to the Size of the Replication-Competent Reservoir. J Virol. 2019;93: pubmed publisher
Statzu M, Jin W, Fray E, Wong A, Kumar M, Ferrer E, et al. CD8+ lymphocytes do not impact SIV reservoir establishment under ART. Nat Microbiol. 2023;8:299-308 pubmed publisher
De Biasi S, Paolini A, Lo Tartaro D, Gibellini L, Cossarizza A. Analysis of Antigen-Specific T and B Cells for Monitoring Immune Protection Against SARS-CoV-2. Curr Protoc. 2023;3:e636 pubmed publisher
Zhang P, Narayanan E, Liu Q, Tsybovsky Y, Boswell K, Ding S, et al. A multiclade env-gag VLP mRNA vaccine elicits tier-2 HIV-1-neutralizing antibodies and reduces the risk of heterologous SHIV infection in macaques. Nat Med. 2021;27:2234-2245 pubmed publisher
Dijkman K, Aguilo N, Boot C, Hofman S, Sombroek C, Vervenne R, et al. Pulmonary MTBVAC vaccination induces immune signatures previously correlated with prevention of tuberculosis infection. Cell Rep Med. 2021;2:100187 pubmed publisher
Vierboom M, Dijkman K, Sombroek C, Hofman S, Boot C, Vervenne R, et al. Stronger induction of trained immunity by mucosal BCG or MTBVAC vaccination compared to standard intradermal vaccination. Cell Rep Med. 2021;2:100185 pubmed publisher
Hoang T, Pino M, Boddapati A, Viox E, Starke C, Upadhyay A, et al. Baricitinib treatment resolves lower-airway macrophage inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques. Cell. 2021;184:460-475.e21 pubmed publisher
Hoang T, Pino M, Boddapati A, Viox E, Starke C, Upadhyay A, et al. Baricitinib treatment resolves lower airway inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques. bioRxiv. 2020;: pubmed publisher
McDaniel M, Kottyan L, Singh H, Pasare C. Suppression of Inflammasome Activation by IRF8 and IRF4 in cDCs Is Critical for T Cell Priming. Cell Rep. 2020;31:107604 pubmed publisher
Harper J, Gordon S, Chan C, Wang H, Lindemuth E, Galardi C, et al. CTLA-4 and PD-1 dual blockade induces SIV reactivation without control of rebound after antiretroviral therapy interruption. Nat Med. 2020;26:519-528 pubmed publisher
Meehan S, Kolyagin G, Parks D, Youngyunpipatkul J, Herzenberg L, Walther G, et al. Automated subset identification and characterization pipeline for multidimensional flow and mass cytometry data clustering and visualization. Commun Biol. 2019;2:229 pubmed publisher
Violari A, Cotton M, Kuhn L, Schramm D, Paximadis M, Loubser S, et al. A child with perinatal HIV infection and long-term sustained virological control following antiretroviral treatment cessation. Nat Commun. 2019;10:412 pubmed publisher
Thyagarajan B, BARCELO H, Crimmins E, Weir D, Minnerath S, Vivek S, et al. Effect of delayed cell processing and cryopreservation on immunophenotyping in multicenter population studies. J Immunol Methods. 2018;463:61-70 pubmed publisher
BARCELO H, Faul J, Crimmins E, Thyagarajan B. A Practical Cryopreservation and Staining Protocol for Immunophenotyping in Population Studies. Curr Protoc Cytom. 2018;84:e35 pubmed publisher
McGary C, Deléage C, Harper J, Micci L, Ribeiro S, Paganini S, et al. CTLA-4+PD-1- Memory CD4+ T Cells Critically Contribute to Viral Persistence in Antiretroviral Therapy-Suppressed, SIV-Infected Rhesus Macaques. Immunity. 2017;47:776-788.e5 pubmed publisher
Xie S, Li J, Wang J, Wu Q, Yang P, Hsu H, et al. IL-17 activates the canonical NF-kappaB signaling pathway in autoimmune B cells of BXD2 mice to upregulate the expression of regulators of G-protein signaling 16. J Immunol. 2010;184:2289-96 pubmed publisher
product information
Antigen :
CD95
Apps. Abbrev. :
FC
Cat # :
305628
Clone :
DX2
Item :
Brilliant Violet 605™ anti-human CD95 (Fas)
Isotype :
Mouse IgG1, κ
Other Names :
Fas, APO-1, TNFRSF6
Size :
100 tests
Price (USD) :
435 USD
Reactivity :
Human, Cynomolgus, Rhesus
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
BV605
Immunogen :
CD95 transfected L cells
Application Notes :
The DX2 antibody is useful for inducing apoptosis of Fas-positive cells. Additional reported applications (for the relevant formats) include: in vitro induction of apoptosis^3 (DX2 antibody is required to be cross-linked for effective induction of apoptosis) and immunohistochemical staining^4,5 of acetone-fixed frozen tissue sections and formalin-fixed paraffin-embedded tissue sections. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 305655 and 305656).Note: EOS9.1 antibody can induce apoptosis without cross-linking.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA