Brilliant Violet 421™ anti-human CD86 | BioLegend 305425 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Brilliant Violet 421™ anti-human CD86

catalog :

305425

quantity :

25 tests

price :

204 USD

clonality :

monoclonal

host :

mouse

conjugate :

BV421

clone name :

IT2.2

reactivity :

human, mouse, rhesus macaque

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 12

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; 1:100; fig 1k	Arenas E, Martínez Sabadell A, Rius Ruiz I, Román Alonso M, Escorihuela M, Luque A, et al. Acquired cancer cell resistance to T cell bispecific antibodies and CAR T targeting HER2 through JAK2 down-modulation. Nat Commun. 2021;12:1237 pubmed publisher
flow cytometry; human; loading ...; fig 9a	Herbst S, Shah A, Mazon Moya M, Marzola V, Jensen B, Reed A, et al. Phagocytosis-dependent activation of a TLR9-BTK-calcineurin-NFAT pathway co-ordinates innate immunity to Aspergillus fumigatus. EMBO Mol Med. 2015;7:240-58 pubmed publisher
	Lah S, Kim S, Kang I, Kim H, Hupperetz C, Jung H, et al. Engineering second-generation TCR-T cells by site-specific integration of TRAF-binding motifs into the CD247 locus. J Immunother Cancer. 2023;11: pubmed publisher
	Parasar P, Bernard M, Ahn S, Kshirsagar S, Nguyen S, Grzesiak G, et al. Isolation and characterization of uterine leukocytes collected using a uterine swab technique. Am J Reprod Immunol. 2022;88:e13614 pubmed publisher
	Felce S, Farnie G, Dustin M, Felce J. RNA-Seq analysis of early transcriptional responses to activation in the leukaemic Jurkat E6.1 T cell line. Wellcome Open Res. 2020;5:42 pubmed publisher
	Wenthe J, Naseri S, Labani Motlagh A, Enblad G, Wikstrom K, Eriksson E, et al. Boosting CAR T-cell responses in lymphoma by simultaneous targeting of CD40/4-1BB using oncolytic viral gene therapy. Cancer Immunol Immunother. 2021;70:2851-2865 pubmed publisher
	Sekine T, Perez Potti A, Rivera Ballesteros O, Stralin K, Gorin J, Olsson A, et al. Robust T Cell Immunity in Convalescent Individuals with Asymptomatic or Mild COVID-19. Cell. 2020;183:158-168.e14 pubmed publisher
	Zhao Y, Lee C, Lin C, Gassen R, Xu X, Huang Z, et al. PD-L1:CD80 Cis-Heterodimer Triggers the Co-stimulatory Receptor CD28 While Repressing the Inhibitory PD-1 and CTLA-4 Pathways. Immunity. 2019;51:1059-1073.e9 pubmed publisher
	Upasani V, Vo H, Ung S, Heng S, Laurent D, Choeung R, et al. Impaired Antibody-Independent Immune Response of B Cells in Patients With Acute Dengue Infection. Front Immunol. 2019;10:2500 pubmed publisher
	Woolsey C, Menicucci A, Cross R, Luthra P, Agans K, Borisevich V, et al. A VP35 Mutant Ebola Virus Lacks Virulence but Can Elicit Protective Immunity to Wild-Type Virus Challenge. Cell Rep. 2019;28:3032-3046.e6 pubmed publisher
	Waight J, Chand D, Dietrich S, Gombos R, Horn T, Gonzalez A, et al. Selective FcγR Co-engagement on APCs Modulates the Activity of Therapeutic Antibodies Targeting T Cell Antigens. Cancer Cell. 2018;33:1033-1047.e5 pubmed publisher
	Eriksson E, Moreno R, Milenova I, Liljenfeldt L, Dieterich L, Christiansson L, et al. Activation of myeloid and endothelial cells by CD40L gene therapy supports T-cell expansion and migration into the tumor microenvironment. Gene Ther. 2017;24:92-103 pubmed publisher

product information

Antigen :

CD86

Apps. Abbrev. :

Cat # :

305425

Clone :

IT2.2

Item :

Brilliant Violet 421™ anti-human CD86

Isotype :

Mouse IgG2b, κ

Other Names :

B7-2, B70

Size :

25 tests

Price (USD) :

204 USD

Reactivity :

Human, Cynomolgus, Rhesus

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

BV421

Application Notes :

Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections^6, Western blotting^3, and blocking of T cell activation^2,4,5. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. Nos. 305449 & 305450).;

more info or order :

BioLegend product webpage