product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Pacific Blue™ anti-human CD86
catalog :
305418
quantity :
100 μg
price :
265 USD
clonality :
monoclonal
host :
mouse
conjugate :
Pacific Blue
clone name :
IT2.2
reactivity :
human, rhesus macaque
application :
flow cytometry
more info or order :
citations: 24
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...
Tan E, Hopkins R, Lim C, Jamuar S, Ong C, Thoon K, et al. Dominant-negative NFKBIA mutation promotes IL-1β production causing hepatic disease with severe immunodeficiency. J Clin Invest. 2020;130:5817-5832 pubmed publisher
  • flow cytometry; rhesus macaque; loading ...
Kasturi S, Kozlowski P, Nakaya H, Burger M, Russo P, Pham M, et al. Adjuvanting a Simian Immunodeficiency Virus Vaccine with Toll-Like Receptor Ligands Encapsulated in Nanoparticles Induces Persistent Antibody Responses and Enhanced Protection in TRIM5α Restrictive Macaques. J Virol. 2017;91: pubmed publisher
  • flow cytometry; human; loading ...; fig 2a
Cheng W, van Asten S, Burns L, Evans H, Walter G, Hashim A, et al. Periodontitis-associated pathogens P. gingivalis and A. actinomycetemcomitans activate human CD14(+) monocytes leading to enhanced Th17/IL-17 responses. Eur J Immunol. 2016;46:2211-21 pubmed publisher
  • flow cytometry; human; fig 4
Brummelman J, Veerman R, Hamstra H, Deuss A, Schuijt T, Sloots A, et al. Bordetella pertussis naturally occurring isolates with altered lipooligosaccharide structure fail to fully mature human dendritic cells. Infect Immun. 2015;83:227-38 pubmed publisher
  • flow cytometry; human
Koido S, Homma S, Okamoto M, Takakura K, Mori M, Yoshizaki S, et al. Treatment with chemotherapy and dendritic cells pulsed with multiple Wilms' tumor 1 (WT1)-specific MHC class I/II-restricted epitopes for pancreatic cancer. Clin Cancer Res. 2014;20:4228-39 pubmed publisher
  • flow cytometry; human
Kobie J, Treanor J, Ritchlin C. Transient decrease in human peripheral blood myeloid dendritic cells following influenza vaccination correlates with induction of serum antibody. Immunol Invest. 2014;43:606-15 pubmed publisher
  • flow cytometry; human
Jitschin R, Braun M, Büttner M, Dettmer Wilde K, Bricks J, Berger J, et al. CLL-cells induce IDOhi CD14+HLA-DRlo myeloid-derived suppressor cells that inhibit T-cell responses and promote TRegs. Blood. 2014;124:750-60 pubmed publisher
  • flow cytometry; human
Wang J, Kobie J, Zhang L, Cochran M, Mosmann T, Ritchlin C, et al. An 11-color flow cytometric assay for identifying, phenotyping, and assessing endocytic ability of peripheral blood dendritic cell subsets in a single platform. J Immunol Methods. 2009;341:106-16 pubmed publisher
Feuerer N, Marzi J, Brauchle E, Carvajal Berrio D, Billing F, Weiss M, et al. Lipidome profiling with Raman microspectroscopy identifies macrophage response to surface topographies of implant materials. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher
Parackova Z, Vrabcová P, Zentsova I, Kayserova J, Richtrova I, Sojka L, et al. Enhanced STAT3 phosphorylation and PD-L1 expression in myeloid dendritic cells indicate impaired IL-27Ralpha signaling in type 1 diabetes. Sci Rep. 2020;10:493 pubmed publisher
Walk J, de Bree L, Graumans W, Stoter R, van Gemert G, van de Vegte Bolmer M, et al. Outcomes of controlled human malaria infection after BCG vaccination. Nat Commun. 2019;10:874 pubmed publisher
Thwe P, Pelgrom L, Cooper R, Beauchamp S, Reisz J, D Alessandro A, et al. Cell-Intrinsic Glycogen Metabolism Supports Early Glycolytic Reprogramming Required for Dendritic Cell Immune Responses. Cell Metab. 2017;26:558-567.e5 pubmed publisher
Rusconi M, Gerardi F, Santus W, Lizio A, Sansone V, Lunetta C, et al. Inflammatory role of dendritic cells in Amyotrophic Lateral Sclerosis revealed by an analysis of patients' peripheral blood. Sci Rep. 2017;7:7853 pubmed publisher
Beljanski V, Chiang C, Kirchenbaum G, Olagnier D, Bloom C, Wong T, et al. Enhanced Influenza Virus-Like Particle Vaccination with a Structurally Optimized RIG-I Agonist as Adjuvant. J Virol. 2015;89:10612-24 pubmed publisher
Teirlinck A, Roestenberg M, Bijker E, Hoffman S, Sauerwein R, Scholzen A. Plasmodium falciparum Infection of Human Volunteers Activates Monocytes and CD16+ Dendritic Cells and Induces Upregulation of CD16 and CD1c Expression. Infect Immun. 2015;83:3732-9 pubmed publisher
Magalhães L, Viana A, Chiari E, Galvão L, Gollob K, Dutra W. Differential Activation of Human Monocytes and Lymphocytes by Distinct Strains of Trypanosoma cruzi. PLoS Negl Trop Dis. 2015;9:e0003816 pubmed publisher
Soema P, Willems G, Jiskoot W, Amorij J, Kersten G. Predicting the influence of liposomal lipid composition on liposome size, zeta potential and liposome-induced dendritic cell maturation using a design of experiments approach. Eur J Pharm Biopharm. 2015;94:427-35 pubmed publisher
de Groen R, Groothuismink Z, Liu B, Boonstra A. IFN-λ is able to augment TLR-mediated activation and subsequent function of primary human B cells. J Leukoc Biol. 2015;98:623-30 pubmed publisher
Chao Y, Kaliaperumal N, Chretien A, Tang S, Lee B, Poidinger M, et al. Human plasmacytoid dendritic cells regulate IFN-α production through activation-induced splicing of IL-18Rα. J Leukoc Biol. 2014;96:1037-46 pubmed publisher
Seguier S, Tartour E, Guérin C, Couty L, Lemitre M, Lallement L, et al. Inhibition of the differentiation of monocyte-derived dendritic cells by human gingival fibroblasts. PLoS ONE. 2013;8:e70937 pubmed publisher
Gustafsson R, Engdahl E, Hammarfjord O, Adikari S, Lourda M, Klingstrom J, et al. Human herpesvirus 6A partially suppresses functional properties of DC without viral replication. PLoS ONE. 2013;8:e58122 pubmed publisher
Tavano B, Galao R, Graham D, Neil S, Aquino V, Fuchs D, et al. Ig-like transcript 7, but not bone marrow stromal cell antigen 2 (also known as HM1.24, tetherin, or CD317), modulates plasmacytoid dendritic cell function in primary human blood leukocytes. J Immunol. 2013;190:2622-30 pubmed publisher
Liu W, Nahar T, Jacobi R, Gijzen K, van Beek J, Hak E, et al. Impaired production of TNF-? by dendritic cells of older adults leads to a lower CD8+ T cell response against influenza. Vaccine. 2012;30:1659-66 pubmed publisher
Mansour H, Laird M, Saleh R, Casrouge A, Eldin N, El Kafrawy S, et al. Circulating plasmacytoid dendritic cells in acutely infected patients with hepatitis C virus genotype 4 are normal in number and phenotype. J Infect Dis. 2010;202:1671-5 pubmed publisher
product information
Antigen :
CD86
Apps. Abbrev. :
FC
Cat # :
305418
Clone :
IT2.2
Item :
Pacific Blue™ anti-human CD86
Isotype :
Mouse IgG2b, κ
Other Names :
B7-2, B70
Size :
100 μg
Price (USD) :
265 USD
Reactivity :
Human, Cynomolgus, Rhesus
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PB
Application Notes :
Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections^6, Western blotting^3, and blocking of T cell activation^2,4,5. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. Nos. 305449 & 305450).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA