product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
APC anti-human CD80
catalog :
305219
quantity :
25 tests
price :
105 USD
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
2D10
reactivity :
human
application :
flow cytometry
more info or order :
citations: 35
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 3s2b
Gregorova M, Morse D, Brignoli T, Steventon J, Hamilton F, Albur M, et al. Post-acute COVID-19 associated with evidence of bystander T-cell activation and a recurring antibiotic-resistant bacterial pneumonia. elife. 2020;9: pubmed publisher
  • flow cytometry; human; loading ...; fig 4b
Duggal N, Beswetherick A, Upton J, Hampson P, Phillips A, Lord J. Depressive symptoms in hip fracture patients are associated with reduced monocyte superoxide production. Exp Gerontol. 2014;54:27-34 pubmed publisher
Xu C, Cheng S, Chen K, Song Q, Liu C, Fan C, et al. Sex Differences in Genomic Features of Hepatitis B-Associated Hepatocellular Carcinoma With Distinct Antitumor Immunity. Cell Mol Gastroenterol Hepatol. 2023;15:327-354 pubmed publisher
Zhang Z, Ji W, Huang J, Zhang Y, Zhou Y, Zhang J, et al. Characterization of the tumour microenvironment phenotypes in malignant tissues and pleural effusion from advanced osteoblastic osteosarcoma patients. Clin Transl Med. 2022;12:e1072 pubmed publisher
Siepe D, Henneberg L, Wilson S, Hess G, Bassik M, Zinn K, et al. Identification of orphan ligand-receptor relationships using a cell-based CRISPRa enrichment screening platform. elife. 2022;11: pubmed publisher
Amo L, D xed ez Garc xed a J, Tamayo Orbegozo E, Maruri N, Larrucea S. Podocalyxin Expressed in Antigen Presenting Cells Promotes Interaction With T Cells and Alters Centrosome Translocation to the Contact Site. Front Immunol. 2022;13:835527 pubmed publisher
Murugesan G, Davidson L, Jannetti L, Crocker P, Weigle B. Quantitative Proteomics of Polarised Macrophages Derived from Induced Pluripotent Stem Cells. Biomedicines. 2022;10: pubmed publisher
Afolabi L, Bi J, Li X, Adeshakin A, Adeshakin F, Wu H, et al. Synergistic Tumor Cytolysis by NK Cells in Combination With a Pan-HDAC Inhibitor, Panobinostat. Front Immunol. 2021;12:701671 pubmed publisher
Fu Y, Zhang Z, Yang Z, Jiang Y, Han X, Xu J, et al. CD27-CD38+ B cells accumulated in early HIV infection exhibit transitional profile and promote HIV disease progression. Cell Rep. 2021;36:109344 pubmed publisher
Yamaguchi S, Hamana H, Shitaoka K, Sukegawa K, Nagata T, Hayee A, et al. TCR function analysis using a novel system reveals the multiple unconventional tumor-reactive T cells in human breast cancer-infiltrating lymphocytes. Eur J Immunol. 2021;51:2306-2316 pubmed publisher
Jost M, Jacobson A, Hussmann J, Cirolia G, Fischbach M, Weissman J. CRISPR-based functional genomics in human dendritic cells. elife. 2021;10: pubmed publisher
Roberts A, Bentley L, Tang T, Stewart F, Pallini C, Juvvanapudi J, et al. Ex vivo modelling of PD-1/PD-L1 immune checkpoint blockade under acute, chronic, and exhaustion-like conditions of T-cell stimulation. Sci Rep. 2021;11:4030 pubmed publisher
Chaumonnot K, Masson S, Sikner H, Bouchard A, Baverel V, Bellaye P, et al. The HSP GRP94 interacts with macrophage intracellular complement C3 and impacts M2 profile during ER stress. Cell Death Dis. 2021;12:114 pubmed publisher
Walter F, Winter E, Rahn S, Heidland J, Meier S, Struzek A, et al. Chitosan nanoparticles as antigen vehicles to induce effective tumor specific T cell responses. PLoS ONE. 2020;15:e0239369 pubmed publisher
Walsh R, Lannan M, Wen Y, Wang X, Moreland C, Willency J, et al. Post-hoc assessment of the immunogenicity of three antibodies reveals distinct immune stimulatory mechanisms. MAbs. 2020;12:1764829 pubmed publisher
Sohrabi Y, Sonntag G, Braun L, Lagache S, Liebmann M, Klotz L, et al. LXR Activation Induces a Proinflammatory Trained Innate Immunity-Phenotype in Human Monocytes. Front Immunol. 2020;11:353 pubmed publisher
Han P, Hanlon D, Arshad N, Lee J, Tatsuno K, Robinson E, et al. Platelet P-selectin initiates cross-presentation and dendritic cell differentiation in blood monocytes. Sci Adv. 2020;6:eaaz1580 pubmed publisher
Fukushima T, Tanaka Y, Hamey F, Chang C, Oki T, Asada S, et al. Discrimination of Dormant and Active Hematopoietic Stem Cells by G0 Marker Reveals Dormancy Regulation by Cytoplasmic Calcium. Cell Rep. 2019;29:4144-4158.e7 pubmed publisher
Zhao Y, Lee C, Lin C, Gassen R, Xu X, Huang Z, et al. PD-L1:CD80 Cis-Heterodimer Triggers the Co-stimulatory Receptor CD28 While Repressing the Inhibitory PD-1 and CTLA-4 Pathways. Immunity. 2019;51:1059-1073.e9 pubmed publisher
Brown C, Gudjonson H, Pritykin Y, Deep D, Lavallée V, Mendoza A, et al. Transcriptional Basis of Mouse and Human Dendritic Cell Heterogeneity. Cell. 2019;179:846-863.e24 pubmed publisher
Frank A, Ebersberger S, Fink A, Lampe S, Weigert A, Schmid T, et al. Apoptotic tumor cell-derived microRNA-375 uses CD36 to alter the tumor-associated macrophage phenotype. Nat Commun. 2019;10:1135 pubmed publisher
Sohrabi Y, Lagache S, Schnack L, Godfrey R, Kahles F, Bruemmer D, et al. mTOR-Dependent Oxidative Stress Regulates oxLDL-Induced Trained Innate Immunity in Human Monocytes. Front Immunol. 2018;9:3155 pubmed publisher
Gkirtzimanaki K, Kabrani E, Nikoleri D, Polyzos A, Blanas A, Sidiropoulos P, et al. IFNα Impairs Autophagic Degradation of mtDNA Promoting Autoreactivity of SLE Monocytes in a STING-Dependent Fashion. Cell Rep. 2018;25:921-933.e5 pubmed publisher
Waight J, Chand D, Dietrich S, Gombos R, Horn T, Gonzalez A, et al. Selective FcγR Co-engagement on APCs Modulates the Activity of Therapeutic Antibodies Targeting T Cell Antigens. Cancer Cell. 2018;33:1033-1047.e5 pubmed publisher
Mertens C, Mora J, Oren B, Grein S, Winslow S, Scholich K, et al. Macrophage-derived lipocalin-2 transports iron in the tumor microenvironment. Oncoimmunology. 2018;7:e1408751 pubmed publisher
Tober J, Maijenburg M, Li Y, Gao L, Hadland B, Gao P, et al. Maturation of hematopoietic stem cells from prehematopoietic stem cells is accompanied by up-regulation of PD-L1. J Exp Med. 2018;215:645-659 pubmed publisher
Redka D, Gutschow M, Grinstein S, Canton J. Differential ability of proinflammatory and anti-inflammatory macrophages to perform macropinocytosis. Mol Biol Cell. 2018;29:53-65 pubmed publisher
Mertens C, Akam E, Rehwald C, Brüne B, Tomat E, Jung M. Intracellular Iron Chelation Modulates the Macrophage Iron Phenotype with Consequences on Tumor Progression. PLoS ONE. 2016;11:e0166164 pubmed publisher
Ball M, Shipman E, Kim H, Liby K, Pioli P. CDDO-Me Redirects Activation of Breast Tumor Associated Macrophages. PLoS ONE. 2016;11:e0149600 pubmed publisher
Hashimoto M, Nasser H, Bhuyan F, Kuse N, Satou Y, Harada S, et al. Fibrocytes Differ from Macrophages but Can Be Infected with HIV-1. J Immunol. 2015;195:4341-50 pubmed publisher
Brummelman J, Veerman R, Hamstra H, Deuss A, Schuijt T, Sloots A, et al. Bordetella pertussis naturally occurring isolates with altered lipooligosaccharide structure fail to fully mature human dendritic cells. Infect Immun. 2015;83:227-38 pubmed publisher
Škrnjug I, Guzmán C, Rueckert C, Ruecker C. Cyclic GMP-AMP displays mucosal adjuvant activity in mice. PLoS ONE. 2014;9:e110150 pubmed publisher
Seguier S, Tartour E, Guérin C, Couty L, Lemitre M, Lallement L, et al. Inhibition of the differentiation of monocyte-derived dendritic cells by human gingival fibroblasts. PLoS ONE. 2013;8:e70937 pubmed publisher
Schubert D, Gordo S, Sabatino J, Vardhana S, Gagnon E, Sethi D, et al. Self-reactive human CD4 T cell clones form unusual immunological synapses. J Exp Med. 2012;209:335-52 pubmed publisher
Jayakumar A, Donovan M, Tripathi V, Ramalho Ortigao M, McDowell M. Leishmania major infection activates NF-kappaB and interferon regulatory factors 1 and 8 in human dendritic cells. Infect Immun. 2008;76:2138-48 pubmed publisher
product information
Antigen :
CD80
Apps. Abbrev. :
FC
Cat # :
305219
Clone :
2D10
Item :
APC anti-human CD80
Isotype :
Mouse IgG1, κ
Other Names :
B7-1, B7, BB1
Size :
25 tests
Price (USD) :
105 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
APC
Application Notes :
Additional reported applications (for the relevant formats) include: in vitro blocking of T cell activation, immunohistochemical staining of acetone-fixed frozen tissue sections^2, immunoprecipitation, and Western blotting^3. The Ultra-LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. Nos. 305245 & 305246).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA