product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PE anti-human CD80
catalog :
305207
quantity :
25 tests
price :
99 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
2D10
reactivity :
human
application :
flow cytometry
more info or order :
citations: 43
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 1b
Piao W, Li L, Saxena V, Iyyathurai J, Lakhan R, Zhang Y, et al. PD-L1 signaling selectively regulates T cell lymphatic transendothelial migration. Nat Commun. 2022;13:2176 pubmed publisher
  • flow cytometry; human; 1:100; loading ...; fig 6f
Liu Y, Wang L, Song Q, Ali M, Crowe W, Kucera G, et al. Intrapleural nano-immunotherapy promotes innate and adaptive immune responses to enhance anti-PD-L1 therapy for malignant pleural effusion. Nat Nanotechnol. 2022;17:206-216 pubmed publisher
  • flow cytometry; human; loading ...; fig s1c
Morrissey M, Byrne R, Nulty C, McCabe N, Lynam Lennon N, Butler C, et al. The tumour microenvironment of the upper and lower gastrointestinal tract differentially influences dendritic cell maturation. BMC Cancer. 2020;20:566 pubmed publisher
  • flow cytometry; human; loading ...; fig 4a
Parrot T, Oger R, Benlalam H, Raingeard de la Blétière D, Jouand N, Coutolleau A, et al. CD40L confers helper functions to human intra-melanoma class-I-restricted CD4+CD8+ double positive T cells. Oncoimmunology. 2016;5:e1250991 pubmed publisher
  • flow cytometry; human; loading ...; fig 1b
Trabanelli S, Lecciso M, Salvestrini V, Cavo M, Očadlíková D, Lemoli R, et al. PGE2-induced IDO1 inhibits the capacity of fully mature DCs to elicit an in vitro antileukemic immune response. J Immunol Res. 2015;2015:253191 pubmed publisher
Nshimiyimana R, Libreros S, Simard M, Chiang N, Rodriguez A, Spur B, et al. Stereochemistry and functions of the new cysteinyl-resolvin, 4S,5R-RCTR1, in efferocytosis and erythrophagocytosis of human senescent erythrocytes. Am J Hematol. 2023;98:1000-1016 pubmed publisher
Wang Y, Song W, Xu Q, Liu Y, Liu H, Guo R, et al. Adjuvant DNA vaccine pNMM promotes enhanced specific immunity and anti-tumor effects. Hum Vaccin Immunother. 2023;19:2202127 pubmed publisher
Lah S, Kim S, Kang I, Kim H, Hupperetz C, Jung H, et al. Engineering second-generation TCR-T cells by site-specific integration of TRAF-binding motifs into the CD247 locus. J Immunother Cancer. 2023;11: pubmed publisher
Wu L, Brzostek J, Sakthi Vale P, Wei Q, Koh C, Ong J, et al. CD28-CAR-T cell activation through FYN kinase signaling rather than LCK enhances therapeutic performance. Cell Rep Med. 2023;4:100917 pubmed publisher
Balan I, Aurelian L, WILLIAMS K, Campbell B, Meeker R, Morrow A. Inhibition of human macrophage activation via pregnane neurosteroid interactions with toll-like receptors: Sex differences and structural requirements. Front Immunol. 2022;13:940095 pubmed publisher
Lertjuthaporn S, Somkird J, Lekmanee K, Atipimonpat A, Sukapirom K, Sawasdipokin H, et al. Extracellular Vesicles from Naegleria fowleri Induce IL-8 Response in THP-1 Macrophage. Pathogens. 2022;11: pubmed publisher
Guo Z, Yuan Y, Chen C, Lin J, Ma Q, Liu G, et al. Durable complete response to neoantigen-loaded dendritic-cell vaccine following anti-PD-1 therapy in metastatic gastric cancer. NPJ Precis Oncol. 2022;6:34 pubmed publisher
Corgnac S, Damei I, Gros G, Caidi A, Terry S, Chouaib S, et al. Cancer stem-like cells evade CD8+CD103+ tumor-resident memory T (TRM) lymphocytes by initiating an epithelial-to-mesenchymal transition program in a human lung tumor model. J Immunother Cancer. 2022;10: pubmed publisher
Morell M, Varela N, Castillejo Lopez C, Coppard C, Luque M, Wu Y, et al. SIDT1 plays a key role in type I IFN responses to nucleic acids in plasmacytoid dendritic cells and mediates the pathogenesis of an imiquimod-induced psoriasis model. EBioMedicine. 2022;76:103808 pubmed publisher
Pi J, Zhang Z, Yang E, Chen L, Zeng L, Chen Y, et al. Nanocages engineered from Bacillus Calmette-Guerin facilitate protective Vγ2Vδ2 T cell immunity against Mycobacterium tuberculosis infection. J Nanobiotechnology. 2022;20:36 pubmed publisher
Chen R, Huang M, Yang X, Chen X, Shi M, Li Z, et al. CALR-TLR4 Complex Inhibits Non-Small Cell Lung Cancer Progression by Regulating the Migration and Maturation of Dendritic Cells. Front Oncol. 2021;11:743050 pubmed publisher
Lewis S, Sureshchandra S, Doratt B, Jimenez V, Stull C, Grant K, et al. Transcriptional, Epigenetic, and Functional Reprogramming of Monocytes From Non-Human Primates Following Chronic Alcohol Drinking. Front Immunol. 2021;12:724015 pubmed publisher
Luque Martin R, Angell D, Kalxdorf M, Bernard S, Thompson W, Eberl H, et al. IFN-γ Drives Human Monocyte Differentiation into Highly Proinflammatory Macrophages That Resemble a Phenotype Relevant to Psoriasis. J Immunol. 2021;207:555-568 pubmed publisher
Pellegrini J, Martin C, Morelli M, Schander J, Tateosian N, Amiano N, et al. PGE2 displays immunosuppressive effects during human active tuberculosis. Sci Rep. 2021;11:13559 pubmed publisher
Costa M, Serra J, McDevitt T, Cabral J, da Silva C, Ferreira F. Dimethyloxalylglycine, a small molecule, synergistically increases the homing and angiogenic properties of human mesenchymal stromal cells when cultured as 3D spheroids. Biotechnol J. 2021;16:e2000389 pubmed publisher
Ganesan R, Henkels K, Shah K, de la Rosa X, Libreros S, Cheemarla N, et al. D-series Resolvins activate Phospholipase D in phagocytes during inflammation and resolution. FASEB J. 2020;34:15888-15906 pubmed publisher
Zhang S, Shrestha C, Wisniewski B, Pham H, Hou X, Li W, et al. Consequences of CRISPR-Cas9-Mediated CFTR Knockout in Human Macrophages. Front Immunol. 2020;11:1871 pubmed publisher
Zhao Y, Lee C, Lin C, Gassen R, Xu X, Huang Z, et al. PD-L1:CD80 Cis-Heterodimer Triggers the Co-stimulatory Receptor CD28 While Repressing the Inhibitory PD-1 and CTLA-4 Pathways. Immunity. 2019;51:1059-1073.e9 pubmed publisher
Nowak W, Grendas L, Sanmarco L, Estecho I, Arena Á, Eberhardt N, et al. Pro-inflammatory monocyte profile in patients with major depressive disorder and suicide behaviour and how ketamine induces anti-inflammatory M2 macrophages by NMDAR and mTOR. EBioMedicine. 2019;50:290-305 pubmed publisher
Hou Z, Xu X, Fu X, Zhou L, Liu S, Tan D. Long non-coding RNA MALAT1 promotes angiogenesis and immunosuppressive properties of HCC cells by sponging miR-140. Am J Physiol Cell Physiol. 2020;318:C649-C663 pubmed publisher
Hagan T, Cortese M, Rouphael N, Boudreau C, Linde C, Maddur M, et al. Antibiotics-Driven Gut Microbiome Perturbation Alters Immunity to Vaccines in Humans. Cell. 2019;178:1313-1328.e13 pubmed publisher
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Kubala M, Punj V, Placencio Hickok V, Fang H, Fernandez G, Sposto R, et al. Plasminogen Activator Inhibitor-1 Promotes the Recruitment and Polarization of Macrophages in Cancer. Cell Rep. 2018;25:2177-2191.e7 pubmed publisher
Du X, Tang F, Liu M, Su J, Zhang Y, Wu W, et al. A reappraisal of CTLA-4 checkpoint blockade in cancer immunotherapy. Cell Res. 2018;28:416-432 pubmed publisher
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Longbrake E, Cantoni C, Chahin S, Cignarella F, Cross A, Piccio L. Dimethyl fumarate induces changes in B- and T-lymphocyte function independent of the effects on absolute lymphocyte count. Mult Scler. 2018;24:728-738 pubmed publisher
Santiago K, Conti B, Cardoso E, Golim M, Sforcin J. Immunomodulatory/anti-inflammatory effects of a propolis-containing mouthwash on human monocytes. Pathog Dis. 2016;74: pubmed
Rosskopf S, Jutz S, Neunkirchner A, Candia M, Jahn Schmid B, Bohle B, et al. Creation of an engineered APC system to explore and optimize the presentation of immunodominant peptides of major allergens. Sci Rep. 2016;6:31580 pubmed publisher
Wang D, Chen J, Li R, Wu G, Sun Z, Wang Z, et al. PAX5 interacts with RIP2 to promote NF-?B activation and drug-resistance in B-lymphoproliferative disorders. J Cell Sci. 2016;129:2261-72 pubmed publisher
Li H, Borrego F, Nagata S, Tolnay M. Fc Receptor-like 5 Expression Distinguishes Two Distinct Subsets of Human Circulating Tissue-like Memory B Cells. J Immunol. 2016;196:4064-74 pubmed publisher
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Lathrop S, Binder K, Starr T, Cooper K, Chong A, Carmody A, et al. Replication of Salmonella enterica Serovar Typhimurium in Human Monocyte-Derived Macrophages. Infect Immun. 2015;83:2661-71 pubmed publisher
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product information
Antigen :
CD80
Apps. Abbrev. :
FC
Cat # :
305207
Clone :
2D10
Item :
PE anti-human CD80
Isotype :
Mouse IgG1, κ
Other Names :
B7-1, B7, BB1
Size :
25 tests
Price (USD) :
99 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PE
Application Notes :
Additional reported applications (for the relevant formats) include: in vitro blocking of T cell activation, immunohistochemical staining of acetone-fixed frozen tissue sections^2, immunoprecipitation, and Western blotting^3. The Ultra-LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. Nos. 305245 & 305246).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA