product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
FITC anti-human CD66b
catalog :
305103
quantity :
25 tests
price :
98 USD
clonality :
monoclonal
host :
mouse
conjugate :
FITC
clone name :
G10F5
reactivity :
human
application :
flow cytometry
more info or order :
citations: 53
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; 1:200; loading ...; fig e1b, e1c
Ramachandran P, Dobie R, Wilson Kanamori J, Dora E, Henderson B, Luu N, et al. Resolving the fibrotic niche of human liver cirrhosis at single-cell level. Nature. 2019;575:512-518 pubmed publisher
  • flow cytometry; human; loading ...; fig s3a
Tamassia N, Arruda Silva F, Calzetti F, Lonardi S, Gasperini S, Gardiman E, et al. A Reappraisal on the Potential Ability of Human Neutrophils to Express and Produce IL-17 Family Members In Vitro: Failure to Reproducibly Detect It. Front Immunol. 2018;9:795 pubmed publisher
  • flow cytometry; human; loading ...; fig 2
Krogh Nielsen M, Hector S, Allen K, Subhi Y, Sørensen T. Altered activation state of circulating neutrophils in patients with neovascular age-related macular degeneration. Immun Ageing. 2017;14:18 pubmed publisher
  • flow cytometry; human
Jitschin R, Braun M, Büttner M, Dettmer Wilde K, Bricks J, Berger J, et al. CLL-cells induce IDOhi CD14+HLA-DRlo myeloid-derived suppressor cells that inhibit T-cell responses and promote TRegs. Blood. 2014;124:750-60 pubmed publisher
Mauracher L, Hell L, Moik F, Krall M, Englisch C, Roi xdf J, et al. Neutrophils in lung cancer patients: Activation potential and neutrophil extracellular trap formation. Res Pract Thromb Haemost. 2023;7:100126 pubmed publisher
Ogishi M, Yang R, Rodriguez R, Golec D, Martin E, Philippot Q, et al. Inherited human ITK deficiency impairs IFN-γ immunity and underlies tuberculosis. J Exp Med. 2023;220: pubmed publisher
Lo M, Amarilla A, Lee J, Albornoz E, Modhiran N, Clark R, et al. SARS-CoV-2 triggers complement activation through interactions with heparan sulfate. Clin Transl Immunology. 2022;11:e1413 pubmed publisher
Sureshchandra S, Zulu M, Doratt B, Jankeel A, Tifrea D, Edwards R, et al. Single-cell RNA sequencing reveals immunological rewiring at the maternal-fetal interface following asymptomatic/mild SARS-CoV-2 infection. Cell Rep. 2022;39:110938 pubmed publisher
Kedage V, Ellerman D, Fei M, Liang W, Zhang G, Cheng E, et al. CLEC5a-directed bispecific antibody for effective cellular phagocytosis. MAbs. 2022;14:2040083 pubmed publisher
Schimek V, Strasser K, Beer A, Göber S, Walterskirchen N, Brostjan C, et al. Tumour cell apoptosis modulates the colorectal cancer immune microenvironment via interleukin-8-dependent neutrophil recruitment. Cell Death Dis. 2022;13:113 pubmed publisher
Ceglia V, Zurawski S, Montes M, Kroll M, Bouteau A, Wang Z, et al. Anti-CD40 Antibody Fused to CD40 Ligand Is a Superagonist Platform for Adjuvant Intrinsic DC-Targeting Vaccines. Front Immunol. 2021;12:786144 pubmed publisher
Kfoury Y, Baryawno N, Severe N, Mei S, Gustafsson K, Hirz T, et al. Human prostate cancer bone metastases have an actionable immunosuppressive microenvironment. Cancer Cell. 2021;39:1464-1478.e8 pubmed publisher
Yang C, Wang Z, Li L, Zhang Z, Jin X, Wu P, et al. Aged neutrophils form mitochondria-dependent vital NETs to promote breast cancer lung metastasis. J Immunother Cancer. 2021;9: pubmed publisher
Saha R, Pradhan S, Shalimar -, Das P, Mishra P, Singh R, et al. Inflammatory signature in acute-on-chronic liver failure includes increased expression of granulocyte genes ELANE, MPO and CD177. Sci Rep. 2021;11:18849 pubmed publisher
Ceglia V, Zurawski S, Montes M, Bouteau A, Wang Z, Ellis J, et al. Anti-CD40 Antibodies Fused to CD40 Ligand Have Superagonist Properties. J Immunol. 2021;207:2060-2076 pubmed publisher
Carre C, Wong G, Narang V, Tan C, Chong J, Chin H, et al. Endoplasmic reticulum stress response and bile acid signatures associate with multi-strain seroresponsiveness during elderly influenza vaccination. iScience. 2021;24:102970 pubmed publisher
Ozuna H, Uriarte S, Demuth D. The Hunger Games: Aggregatibacter actinomycetemcomitans Exploits Human Neutrophils As an Epinephrine Source for Survival. Front Immunol. 2021;12:707096 pubmed publisher
Fraccarollo D, Neuser J, M xf6 ller J, Riehle C, Galuppo P, Bauersachs J. Expansion of CD10neg neutrophils and CD14+HLA-DRneg/low monocytes driving proinflammatory responses in patients with acute myocardial infarction. elife. 2021;10: pubmed publisher
Appios A, Thomas J, McGovern N. Isolation of First-Trimester and Full-term Human Placental Hofbauer Cells. Bio Protoc. 2021;11:e4044 pubmed publisher
Reif T, Dyckhoff G, Hohenberger R, Kolbe C, Gruell H, Klein F, et al. Contact-dependent inhibition of HIV-1 replication in ex vivo human tonsil cultures by polymorphonuclear neutrophils. Cell Rep Med. 2021;2:100317 pubmed publisher
Seery V, Raiden S, Algieri S, Grisol xed a N, Filippo D, De Carli N, et al. Blood neutrophils from children with COVID-19 exhibit both inflammatory and anti-inflammatory markers. EBioMedicine. 2021;67:103357 pubmed publisher
Margaroli C, Moncada Giraldo D, Gulick D, Dobosh B, Giacalone V, Forrest O, et al. Transcriptional firing represses bactericidal activity in cystic fibrosis airway neutrophils. Cell Rep Med. 2021;2:100239 pubmed publisher
Szabo P, Dogra P, Gray J, Wells S, Connors T, Weisberg S, et al. Longitudinal profiling of respiratory and systemic immune responses reveals myeloid cell-driven lung inflammation in severe COVID-19. Immunity. 2021;54:797-814.e6 pubmed publisher
Guo Y, Gao F, Wang Q, Wang K, Pan S, Pan Z, et al. Differentiation of HL-60 cells in serum-free hematopoietic cell media enhances the production of neutrophil extracellular traps. Exp Ther Med. 2021;21:353 pubmed publisher
Mao F, Lv Y, Hao C, Teng Y, Liu Y, Cheng P, et al. Helicobacter pylori-Induced Rev-erbα Fosters Gastric Bacteria Colonization by Impairing Host Innate and Adaptive Defense. Cell Mol Gastroenterol Hepatol. 2021;12:395-425 pubmed publisher
Louka E, Povinelli B, Rodriguez Meira A, Buck G, Wen W, Wang G, et al. Heterogeneous disease-propagating stem cells in juvenile myelomonocytic leukemia. J Exp Med. 2021;218: pubmed publisher
De Domenico E, Bonaguro L, Schulte Schrepping J, Becker M, Händler K, Schultze J. Optimized workflow for single-cell transcriptomics on infectious diseases including COVID-19. STAR Protoc. 2020;1:100233 pubmed publisher
Rodriguez Meira A, O Sullivan J, Rahman H, Mead A. TARGET-Seq: A Protocol for High-Sensitivity Single-Cell Mutational Analysis and Parallel RNA Sequencing. STAR Protoc. 2020;1:100125 pubmed publisher
Holokai L, Chakrabarti J, Lundy J, Croagh D, Adhikary P, Richards S, et al. Murine- and Human-Derived Autologous Organoid/Immune Cell Co-Cultures as Pre-Clinical Models of Pancreatic Ductal Adenocarcinoma. Cancers (Basel). 2020;12: pubmed publisher
Krishnan S, O Boyle C, Smith C, Hulme S, Allan S, Grainger J, et al. A hyperacute immune map of ischaemic stroke patients reveals alterations to circulating innate and adaptive cells. Clin Exp Immunol. 2021;203:458-471 pubmed publisher
Zhang Y, Dong X, Bai L, Shang X, Zeng Y. MUC1-induced immunosuppression in colon cancer can be reversed by blocking the PD1/PDL1 signaling pathway. Oncol Lett. 2020;20:317 pubmed publisher
Fan Z, Mikulski Z, McArdle S, Sundd P, Ley K. Super-STORM: Molecular Modeling to Achieve Single-molecule Localization with STORM Microscopy. STAR Protoc. 2020;1:100012 pubmed publisher
Hess N, Hudson A, Hematti P, Gumperz J. Early T Cell Activation Metrics Predict Graft-versus-Host Disease in a Humanized Mouse Model of Hematopoietic Stem Cell Transplantation. J Immunol. 2020;205:272-281 pubmed publisher
Miralda I, Vashishta A, Rogers M, Rouchka E, Li X, Waigel S, et al. Whole Transcriptome Analysis Reveals That Filifactor alocis Modulates TNFα-Stimulated MAPK Activation in Human Neutrophils. Front Immunol. 2020;11:497 pubmed publisher
Callahan S, Doster R, Jackson J, Kelley B, Gaddy J, Johnson J. Induction of neutrophil extracellular traps by Campylobacter jejuni. Cell Microbiol. 2020;:e13210 pubmed publisher
Simon S, Hu X, Panten J, Grees M, Renders S, Thomas D, et al. Eosinophil accumulation predicts response to melanoma treatment with immune checkpoint inhibitors. Oncoimmunology. 2020;9:1727116 pubmed publisher
Gomez I, Ward B, Souilhol C, Recarti C, Ariaans M, Johnston J, et al. Neutrophil microvesicles drive atherosclerosis by delivering miR-155 to atheroprone endothelium. Nat Commun. 2020;11:214 pubmed publisher
Pulsifer A, Vashishta A, Reeves S, Wolfe J, Palace S, Proulx M, et al. Redundant and Cooperative Roles for Yersinia pestis Yop Effectors in the Inhibition of Human Neutrophil Exocytic Responses Revealed by Gain-of-Function Approach. Infect Immun. 2020;88: pubmed publisher
Zhao Z, Luo Z, Yang Q, Chang H, Liu P, Li Z, et al. Neutrophil-Derived MRP14 Supports Plasma Cell Commitment and Protects Myeloma Cells from Apoptosis. J Immunol Res. 2019;2019:9561350 pubmed publisher
Rodriguez Meira A, Buck G, Clark S, Povinelli B, Alcolea V, Louka E, et al. Unravelling Intratumoral Heterogeneity through High-Sensitivity Single-Cell Mutational Analysis and Parallel RNA Sequencing. Mol Cell. 2019;73:1292-1305.e8 pubmed publisher
Franco L, Gadkari M, Howe K, Sun J, Kardava L, Kumar P, et al. Immune regulation by glucocorticoids can be linked to cell type-dependent transcriptional responses. J Exp Med. 2019;216:384-406 pubmed publisher
Bonegio R, Lin J, BEAUDETTE ZLATANOVA B, York M, Menn Josephy H, Yasuda K. Lupus-Associated Immune Complexes Activate Human Neutrophils in an FcγRIIA-Dependent but TLR-Independent Response. J Immunol. 2019;202:675-683 pubmed publisher
Ackermann M, Kempf H, Hetzel M, Hesse C, Hashtchin A, Brinkert K, et al. Bioreactor-based mass production of human iPSC-derived macrophages enables immunotherapies against bacterial airway infections. Nat Commun. 2018;9:5088 pubmed publisher
Osorio F, Rosendahl Huber A, Oka R, Verheul M, Patel S, Hasaart K, et al. Somatic Mutations Reveal Lineage Relationships and Age-Related Mutagenesis in Human Hematopoiesis. Cell Rep. 2018;25:2308-2316.e4 pubmed publisher
Stojkov D, Amini P, Oberson K, Sokollik C, Duppenthaler A, Simon H, et al. ROS and glutathionylation balance cytoskeletal dynamics in neutrophil extracellular trap formation. J Cell Biol. 2017;216:4073-4090 pubmed publisher
Kubo M, Satoh T, Ishiyama H, Tabata K, Tsumura H, Komori S, et al. Enhanced activated T cell subsets in prostate cancer patients receiving iodine-125 low-dose-rate prostate brachytherapy. Oncol Rep. 2018;39:417-424 pubmed publisher
SenGupta S, Hittle L, Ernst R, Uriarte S, Mitchell T. A Pseudomonas aeruginosa hepta-acylated lipid A variant associated with cystic fibrosis selectively activates human neutrophils. J Leukoc Biol. 2016;100:1047-1059 pubmed
Mueller Leisse J, Brueggemann S, Bouzani M, Schmitt A, Einsele H, Loeffler J. Polymorphonuclear neutrophils and granulocytic myeloid-derived suppressor cells inhibit natural killer cell activity toward Aspergillus fumigatus. Med Mycol. 2015;53:622-9 pubmed publisher
Heim C, Vidlak D, Scherr T, Hartman C, Garvin K, Kielian T. IL-12 promotes myeloid-derived suppressor cell recruitment and bacterial persistence during Staphylococcus aureus orthopedic implant infection. J Immunol. 2015;194:3861-3872 pubmed publisher
Meinke P, Schneiderat P, Srsen V, Korfali N, Lê Thành P, Cowan G, et al. Abnormal proliferation and spontaneous differentiation of myoblasts from a symptomatic female carrier of X-linked Emery-Dreifuss muscular dystrophy. Neuromuscul Disord. 2015;25:127-36 pubmed publisher
Little M, Al Ani B, Ren S, Al Nuaimi H, Leite M, Alpers C, et al. Anti-proteinase 3 anti-neutrophil cytoplasm autoantibodies recapitulate systemic vasculitis in mice with a humanized immune system. PLoS ONE. 2012;7:e28626 pubmed publisher
Pliyev B, Sumarokov A, Buriachkovskaia L, Menshikov M. Extracellular acidosis promotes neutrophil transdifferentiation to MHC class II-expressing cells. Cell Immunol. 2011;271:214-8 pubmed publisher
Nijnik A, Madera L, Ma S, Waldbrook M, Elliott M, Easton D, et al. Synthetic cationic peptide IDR-1002 provides protection against bacterial infections through chemokine induction and enhanced leukocyte recruitment. J Immunol. 2010;184:2539-50 pubmed publisher
product information
Antigen :
CD66b
Apps. Abbrev. :
FC
Cat # :
305103
Clone :
G10F5
Item :
FITC anti-human CD66b
Isotype :
Mouse IgM, κ
Other Names :
CD67, CGM6, NCA-95, CEACAM8
Size :
25 tests
Price (USD) :
98 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
FITC
Application Notes :
Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen, formalin-fixed paraffin-embedded tissue sections, and spatial biology (IBEX)^5,6.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA