Ultra-LEAF™ Purified anti-human CD64 | BioLegend 305047 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Ultra-LEAF™ Purified anti-human CD64

catalog :

305047

quantity :

100 μg

price :

220 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

10.1

reactivity :

human

application :

neutralization, flow cytometry, immunohistochemistry - frozen section

more info or order :

BioLegend product webpage

citations: 5

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig 7a, 7c, 7e	Rasoulouniriana D, Santana Magal N, Gutwillig A, Farhat Younis L, Wine Y, Saperia C, et al. A distinct subset of FcγRI-expressing Th1 cells exert antibody-mediated cytotoxic activity. J Clin Invest. 2019;129:4151-4164 pubmed publisher
	Gimpel A, Maccataio A, Unterweger H, Sokolova M, Schett G, Steffen U. IgA Complexes Induce Neutrophil Extracellular Trap Formation More Potently Than IgG Complexes. Front Immunol. 2021;12:761816 pubmed publisher
	Yamin R, Jones A, Hoffmann H, Schäfer A, Kao K, Francis R, et al. Fc-engineered antibody therapeutics with improved anti-SARS-CoV-2 efficacy. Nature. 2021;599:465-470 pubmed publisher
	Caielli S, Cardenas J, de Jesus A, Baisch J, Walters L, Blanck J, et al. Erythroid mitochondrial retention triggers myeloid-dependent type I interferon in human SLE. Cell. 2021;184:4464-4479.e19 pubmed publisher
	Gruber C, Patel R, Trachtman R, Lepow L, Amanat F, Krammer F, et al. Mapping Systemic Inflammation and Antibody Responses in Multisystem Inflammatory Syndrome in Children (MIS-C). Cell. 2020;183:982-995.e14 pubmed publisher

product information

Antigen :

CD64

Apps. Abbrev. :

FC, IHC-F, Block

Cat # :

305047

Clone :

10.1

Item :

Ultra-LEAF™ Purified anti-human CD64

Isotype :

Mouse IgG1, κ

Other Names :

FcγRI, FcR I, FCGR1A

Size :

100 μg

Price (USD) :

220 USD

Reactivity :

Human, Cynomolgus, Rhesus

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

ULEAF

Immunogen :

Human rheumatoid synovial fluid cells and fibronectin-purified monocytes.

Application Notes :

Clone 10.1 recognizes the EC3 epitope of CD64. While both contain the EC3 domain, in-house testing suggests that clone 10.1 preferentially binds to CD64A (FcγRIA), but not CD64B (FcγRIB). Additional reported applications (for the relevant formats) include: blocking of human IgG3 and murine IgG2a binding to FcγRI^2,5,6,11 and immunohistochemical staining of acetone-fixed frozen tissue sections^12.;

more info or order :

BioLegend product webpage