product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Alexa Fluor® 647 anti-human CD62P (P-Selectin)
catalog :
304918
quantity :
100 tests
price :
265 USD
clonality :
monoclonal
host :
mouse
conjugate :
AF647
clone name :
AK4
reactivity :
human
application :
flow cytometry
more info or order :
citations: 14
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; 5:100; loading ...
Chioh F, Fong S, Young B, Wu K, Siau A, Krishnan S, et al. Convalescent COVID-19 patients are susceptible to endothelial dysfunction due to persistent immune activation. elife. 2021;10: pubmed publisher
  • flow cytometry; human; loading ...; fig 2e
Loelius S, Lannan K, Blumberg N, Phipps R, Spinelli S. The HIV protease inhibitor, ritonavir, dysregulates human platelet function in vitro. Thromb Res. 2018;169:96-104 pubmed publisher
Huang J, Jooss N, Fern xe1 ndez D, Sickmann A, Garc xed a x, Wichapong K, et al. Roles of Focal Adhesion Kinase PTK2 and Integrin αIIbβ3 Signaling in Collagen- and GPVI-Dependent Thrombus Formation under Shear. Int J Mol Sci. 2022;23: pubmed publisher
Cruz M, Bohinc D, Andraska E, Alvikas J, Raghunathan S, Masters N, et al. Nanomedicine platform for targeting activated neutrophils and neutrophil-platelet complexes using an α1-antitrypsin-derived peptide motif. Nat Nanotechnol. 2022;17:1004-1014 pubmed publisher
Hrdinova J, Fernández D, Ercig B, Tullemans B, Suylen D, Agten S, et al. Structure-Based Cyclic Glycoprotein Ibα-Derived Peptides Interfering with von Willebrand Factor-Binding, Affecting Platelet Aggregation under Shear. Int J Mol Sci. 2022;23: pubmed publisher
Fernández D, Provenzale I, Cheung H, van Groningen J, Tullemans B, Veninga A, et al. Ultra-high-throughput Ca2+ assay in platelets to distinguish ITAM-linked and G-protein-coupled receptor activation. iScience. 2022;25:103718 pubmed publisher
Sachs L, Wesche J, Lenkeit L, Greinacher A, Bender M, Otto O, et al. Ex vivo anticoagulants affect human blood platelet biomechanics with implications for high-throughput functional mechanophenotyping. Commun Biol. 2022;5:86 pubmed publisher
Jahn K, Handtke S, Palankar R, Weißmüller S, Nouailles G, Kohler T, et al. Pneumolysin induces platelet destruction, not platelet activation, which can be prevented by immunoglobulin preparations in vitro. Blood Adv. 2020;4:6315-6326 pubmed publisher
Han P, Hanlon D, Arshad N, Lee J, Tatsuno K, Robinson E, et al. Platelet P-selectin initiates cross-presentation and dendritic cell differentiation in blood monocytes. Sci Adv. 2020;6:eaaz1580 pubmed publisher
Zhu Y, Smith D, Zhou Y, Li Y, Yu J, Lee D, et al. Development of Hematopoietic Stem Cell-Engineered Invariant Natural Killer T Cell Therapy for Cancer. Cell Stem Cell. 2019;25:542-557.e9 pubmed publisher
Jooss N, De Simone I, Provenzale I, Fernández D, Brouns S, Farndale R, et al. Role of Platelet Glycoprotein VI and Tyrosine Kinase Syk in Thrombus Formation on Collagen-Like Surfaces. Int J Mol Sci. 2019;20: pubmed publisher
Loelius S, Spinelli S, Lannan K, Phipps R. In Vitro Methods to Characterize the Effects of Tobacco and Nontobacco Products on Human Platelet Function. Curr Protoc Toxicol. 2018;76:e46 pubmed publisher
Modery Pawlowski C, Tian L, Ravikumar M, Wong T, Sen Gupta A. In vitro and in vivo hemostatic capabilities of a functionally integrated platelet-mimetic liposomal nanoconstruct. Biomaterials. 2013;34:3031-41 pubmed publisher
Verheul H, Lolkema M, Qian D, Hilkes Y, Liapi E, Akkerman J, et al. Platelets take up the monoclonal antibody bevacizumab. Clin Cancer Res. 2007;13:5341-7 pubmed
product information
Antigen :
CD62P
Apps. Abbrev. :
FC
Cat # :
304918
Clone :
AK4
Item :
Alexa Fluor® 647 anti-human CD62P (P-Selectin)
Isotype :
Mouse IgG1, κ
Other Names :
GMP-140, PADGEM
Size :
100 tests
Price (USD) :
265 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
A647
Application Notes :
Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections^4 and in vitro blocking of adhesion of platelets^1. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 304947 & 304948).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA