product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PE anti-human CD62P (P-Selectin)
catalog :
304906
quantity :
100 tests
price :
237 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
AK4
reactivity :
human
application :
flow cytometry
more info or order :
citations: 24
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 1d
Hally K, La Flamme A, Larsen P, Harding S. Toll-like receptor 9 expression and activation in acute coronary syndrome patients on dual anti-platelet therapy. Thromb Res. 2016;148:89-95 pubmed publisher
  • flow cytometry; human; fig 1
Deng W, Xu Y, Chen W, Paul D, Syed A, Dragovich M, et al. Platelet clearance via shear-induced unfolding of a membrane mechanoreceptor. Nat Commun. 2016;7:12863 pubmed publisher
Li L, Xu X, Lv K, Zheng G, Wang H, Chen S, et al. Asebogenin suppresses thrombus formation via inhibition of Syk phosphorylation. Br J Pharmacol. 2023;180:287-307 pubmed publisher
Cano Mendez A, Garc xed a Larragoiti N, Damian Vazquez M, Guzman Cancino P, Lopez Castaneda S, Ochoa Zarzosa A, et al. Platelet Reactivity and Inflammatory Phenotype Induced by Full-Length Spike SARS-CoV-2 Protein and Its RBD Domain. Int J Mol Sci. 2022;23: pubmed publisher
Kemble S, Dalby A, Lowe G, Nicolson P, Watson S, Senis Y, et al. Analysis of preplatelets and their barbell platelet derivatives by imaging flow cytometry. Blood Adv. 2022;6:2932-2946 pubmed publisher
Li L, Ding Q, Zhou J, Wu Y, Zhang M, Guo X, et al. Distinct binding kinetics of E-, P- and L-selectins to CD44. FEBS J. 2022;289:2877-2894 pubmed publisher
Slingsby M, Vijey P, Tsai I, Roweth H, Couldwell G, Wilkie A, et al. Sequence-specific 2'-O-methoxyethyl antisense oligonucleotides activate human platelets through glycoprotein VI, triggering formation of platelet-leukocyte aggregates. Haematologica. 2022;107:519-531 pubmed publisher
Buijsers B, Garishah F, Riswari S, van Ast R, Pramudo S, Tunjungputri R, et al. Increased Plasma Heparanase Activity and Endothelial Glycocalyx Degradation in Dengue Patients Is Associated With Plasma Leakage. Front Immunol. 2021;12:759570 pubmed publisher
Petersen Uribe x, Kremser M, Rohlfing A, Castor T, Kolb K, Dicenta V, et al. Platelet-Derived PCSK9 Is Associated with LDL Metabolism and Modulates Atherothrombotic Mechanisms in Coronary Artery Disease. Int J Mol Sci. 2021;22: pubmed publisher
Marsden A, Riley D, Barry A, Khalil J, Guinn B, Kemp N, et al. Inhibition of Arginine Methylation Impairs Platelet Function. ACS Pharmacol Transl Sci. 2021;4:1567-1577 pubmed publisher
Lee S, Yu Y, Trimpert J, Benthani F, Mairhofer M, Richter Pechanska P, et al. Virus-induced senescence is a driver and therapeutic target in COVID-19. Nature. 2021;599:283-289 pubmed publisher
Garcia Larragoiti N, Kim Y, Lopez Camacho C, Cano Mendez A, Lopez Castaneda S, Hernández Hernández D, et al. Platelet activation and aggregation response to dengue virus nonstructural protein 1 and domains. J Thromb Haemost. 2021;: pubmed publisher
Machata S, Sreekantapuram S, Hünniger K, Kurzai O, Dunker C, Schubert K, et al. Significant Differences in Host-Pathogen Interactions Between Murine and Human Whole Blood. Front Immunol. 2020;11:565869 pubmed publisher
Yoon H, Kim E, Ko Y. SLAMF1 contributes to cell survival through the AKT signaling pathway in Farage cells. PLoS ONE. 2020;15:e0238791 pubmed publisher
Bennett J, Mastrangelo M, Ture S, Smith C, Loelius S, Berg R, et al. The choline transporter Slc44a2 controls platelet activation and thrombosis by regulating mitochondrial function. Nat Commun. 2020;11:3479 pubmed publisher
Han P, Hanlon D, Arshad N, Lee J, Tatsuno K, Robinson E, et al. Platelet P-selectin initiates cross-presentation and dendritic cell differentiation in blood monocytes. Sci Adv. 2020;6:eaaz1580 pubmed publisher
Ye Z, Zhang S, Liu Y, Wang S, Zhang J, Huang R. A Peptide Analogue of Selectin Ligands Attenuated Atherosclerosis by Inhibiting Monocyte Activation. Mediators Inflamm. 2019;2019:8709583 pubmed publisher
Sung P, Huang T, Hsieh S. Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2. Nat Commun. 2019;10:2402 pubmed publisher
Karampini E, Schillemans M, Hofman M, van Alphen F, de Boer M, Kuijpers T, et al. Defective AP-3-dependent VAMP8 trafficking impairs Weibel-Palade body exocytosis in Hermansky-Pudlak Syndrome type 2 blood outgrowth endothelial cells. Haematologica. 2019;: pubmed publisher
Best M, Sol N, In t Veld S, Vancura A, Muller M, Niemeijer A, et al. Swarm Intelligence-Enhanced Detection of Non-Small-Cell Lung Cancer Using Tumor-Educated Platelets. Cancer Cell. 2017;32:238-252.e9 pubmed publisher
Artemenko E, Yakimenko A, Pichugin A, Ataullakhanov F, Panteleev M. Calpain-controlled detachment of major glycoproteins from the cytoskeleton regulates adhesive properties of activated phosphatidylserine-positive platelets. Biochem J. 2016;473:435-48 pubmed publisher
Crooks M, Fahim A, Naseem K, Morice A, Hart S. Increased platelet reactivity in idiopathic pulmonary fibrosis is mediated by a plasma factor. PLoS ONE. 2014;9:e111347 pubmed publisher
Zhang S, Yuan J, Yu M, Fan H, Guo Z, Yang R, et al. IL-17A facilitates platelet function through the ERK2 signaling pathway in patients with acute coronary syndrome. PLoS ONE. 2012;7:e40641 pubmed publisher
Welsh J, Charonko J, Salmanzadeh A, Drahos K, Shafiee H, Stremler M, et al. Disabled-2 modulates homotypic and heterotypic platelet interactions by binding to sulfatides. Br J Haematol. 2011;154:122-33 pubmed publisher
product information
Antigen :
CD62P
Apps. Abbrev. :
FC
Cat # :
304906
Clone :
AK4
Item :
PE anti-human CD62P (P-Selectin)
Isotype :
Mouse IgG1, κ
Other Names :
GMP-140, PADGEM
Size :
100 tests
Price (USD) :
237 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PE
Application Notes :
Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections^4 and in vitro blocking of adhesion of platelets^1. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 304947 & 304948).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA