product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
FITC anti-human CD62P (P-Selectin)
catalog :
304903
quantity :
25 tests
price :
84 USD
clonality :
monoclonal
host :
mouse
conjugate :
FITC
clone name :
AK4
reactivity :
human
application :
flow cytometry
more info or order :
citations: 15
Reference
Ma X, Liang J, Zhu G, Bhoria P, Shoara A, MacKeigan D, et al. SARS-CoV-2 RBD and Its Variants Can Induce Platelet Activation and Clearance: Implications for Antibody Therapy and Vaccinations against COVID-19. Research (Wash D C). 2023;6:0124 pubmed publisher
Slingsby M, Vijey P, Tsai I, Roweth H, Couldwell G, Wilkie A, et al. Sequence-specific 2'-O-methoxyethyl antisense oligonucleotides activate human platelets through glycoprotein VI, triggering formation of platelet-leukocyte aggregates. Haematologica. 2022;107:519-531 pubmed publisher
Duan X, Perveen R, Dandamudi A, Adili R, Johnson J, Funk K, et al. Pharmacologic targeting of Cdc42 GTPase by a small molecule Cdc42 activity-specific inhibitor prevents platelet activation and thrombosis. Sci Rep. 2021;11:13170 pubmed publisher
Jiang Y, Tang Y, Hoover C, Kondo Y, Huang D, Restagno D, et al. Kupffer cell receptor CLEC4F is important for the destruction of desialylated platelets in mice. Cell Death Differ. 2021;28:3009-3021 pubmed publisher
Dregalla R, Uribe Y, Bodor M. Effect of local anesthetics on platelet physiology and function. J Orthop Res. 2021;39:2744-2754 pubmed publisher
Reitsma S, Pang J, Raghunathan V, Shatzel J, Lorentz C, Tucker E, et al. Role of platelets in regulating activated coagulation factor XI activity. Am J Physiol Cell Physiol. 2021;320:C365-C374 pubmed publisher
Long C, Liu M, Tian H, Li Y, Wu F, Mwangi J, et al. Potential Role of Platelet-Activating C-Type Lectin-Like Proteins in Viper Envenomation Induced Thrombotic Microangiopathy Symptom. Toxins (Basel). 2020;12: pubmed publisher
Xu P, Tang K, Ma J, Zhang H, Wang D, Zhu L, et al. Chemotherapeutic Tumor Microparticles Elicit a Neutrophil Response Targeting Malignant Pleural Effusions. Cancer Immunol Res. 2020;8:1193-1205 pubmed publisher
Bhat A, Das S, Yadav G, Chaudhary S, Vyas A, Islam M, et al. Hyperoxidized Albumin Modulates Platelets and Promotes Inflammation Through CD36 Receptor in Severe Alcoholic Hepatitis. Hepatol Commun. 2020;4:50-65 pubmed publisher
Costa B, Eisemann T, Strelau J, Spaan I, Korshunov A, Liu H, et al. Intratumoral platelet aggregate formation in a murine preclinical glioma model depends on podoplanin expression on tumor cells. Blood Adv. 2019;3:1092-1102 pubmed publisher
Hijmans J, Stockelman K, Garcia V, Levy M, Brewster L, Bammert T, et al. Circulating Microparticles Are Elevated in Treated HIV -1 Infection and Are Deleterious to Endothelial Cell Function. J Am Heart Assoc. 2019;8:e011134 pubmed publisher
Gillespie S, Holloway P, Becker F, Rauzi F, Vital S, Taylor K, et al. The isothiocyanate sulforaphane modulates platelet function and protects against cerebral thrombotic dysfunction. Br J Pharmacol. 2018;175:3333-3346 pubmed publisher
Ansari M, Nadeem A, Attia S, Bakheet S, Raish M, Ahmad S. Adenosine A2A receptor modulates neuroimmune function through Th17/retinoid-related orphan receptor gamma t (ROR?t) signaling in a BTBR T+ Itpr3tf/J mouse model of autism. Cell Signal. 2017;36:14-24 pubmed publisher
Takayama N, Nishimura S, Nakamura S, Shimizu T, Ohnishi R, Endo H, et al. Transient activation of c-MYC expression is critical for efficient platelet generation from human induced pluripotent stem cells. J Exp Med. 2010;207:2817-30 pubmed publisher
Yen Y, Liao F, Hsiao C, Kao C, Chen Y, Wu Hsieh B. Modeling the early events of severe acute respiratory syndrome coronavirus infection in vitro. J Virol. 2006;80:2684-93 pubmed
product information
Antigen :
CD62P
Apps. Abbrev. :
FC
Cat # :
304903
Clone :
AK4
Item :
FITC anti-human CD62P (P-Selectin)
Isotype :
Mouse IgG1, κ
Other Names :
GMP-140, PADGEM
Size :
25 tests
Price (USD) :
84 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
FITC
Application Notes :
Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections^4 and in vitro blocking of adhesion of platelets^1. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 304947 & 304948).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA