product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Brilliant Violet 785™ anti-human CD62L
catalog :
304830
quantity :
100 tests
price :
418 USD
clonality :
monoclonal
host :
mouse
conjugate :
Brilliant Violet 785
clone name :
DREG-56
reactivity :
human
application :
immunocytochemistry, flow cytometry
more info or order :
citations: 19
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 2f
Boardman D, Philippeos C, Fruhwirth G, Ibrahim M, Hannen R, Cooper D, et al. Expression of a Chimeric Antigen Receptor Specific for Donor HLA Class I Enhances the Potency of Human Regulatory T Cells in Preventing Human Skin Transplant Rejection. Am J Transplant. 2017;17:931-943 pubmed publisher
  • immunocytochemistry; human; loading ...; fig s3c
Jung Y, Riven I, Feigelson S, Kartvelishvily E, Tohya K, Miyasaka M, et al. Three-dimensional localization of T-cell receptors in relation to microvilli using a combination of superresolution microscopies. Proc Natl Acad Sci U S A. 2016;113:E5916-E5924 pubmed
  • flow cytometry; human; loading ...; fig s9
Zwang N, Zhang R, Germana S, Fan M, Hastings W, Cao A, et al. Selective Sparing of Human Tregs by Pharmacologic Inhibitors of the Phosphatidylinositol 3-Kinase and MEK Pathways. Am J Transplant. 2016;16:2624-38 pubmed publisher
  • flow cytometry; human; loading ...; fig s1a
Schulz A, Mälzer J, Domingo C, Jürchott K, Grützkau A, Babel N, et al. Low Thymic Activity and Dendritic Cell Numbers Are Associated with the Immune Response to Primary Viral Infection in Elderly Humans. J Immunol. 2015;195:4699-711 pubmed publisher
  • flow cytometry; human; loading ...
Weist B, Wehler P, El Ahmad L, Schmueck Henneresse M, Millward J, Nienen M, et al. A revised strategy for monitoring BKV-specific cellular immunity in kidney transplant patients. Kidney Int. 2015;88:1293-1303 pubmed publisher
  • flow cytometry; human; loading ...; fig 2f
van der Waart A, van de Weem N, Maas F, Kramer C, Kester M, Falkenburg J, et al. Inhibition of Akt signaling promotes the generation of superior tumor-reactive T cells for adoptive immunotherapy. Blood. 2014;124:3490-500 pubmed publisher
Reuschl A, Mesner D, Shivkumar M, Whelan M, Pallett L, Guerra Assun xe7 xe3 o J, et al. HIV-1 Vpr drives a tissue residency-like phenotype during selective infection of resting memory T cells. Cell Rep. 2022;39:110650 pubmed publisher
Vardam Kaur T, Pathangey L, McCormick D, Bergsagel P, Cohen P, Gendler S. Multipeptide stimulated PBMCs generate TEM/TCM for adoptive cell therapy in multiple myeloma. Oncotarget. 2021;12:2051-2067 pubmed publisher
Abdul Jawad S, Baù L, Alaguthurai T, Del Molino Del Barrio I, Laing A, Hayday T, et al. Acute Immune Signatures and Their Legacies in Severe Acute Respiratory Syndrome Coronavirus-2 Infected Cancer Patients. Cancer Cell. 2021;39:257-275.e6 pubmed publisher
Huang X, Williams J, Chang R, Li Z, Burnett C, Hernández López R, et al. DNA scaffolds enable efficient and tunable functionalization of biomaterials for immune cell modulation. Nat Nanotechnol. 2021;16:214-223 pubmed publisher
Laing A, Lorenc A, Del Molino Del Barrio I, Das A, Fish M, Monin L, et al. A dynamic COVID-19 immune signature includes associations with poor prognosis. Nat Med. 2020;26:1623-1635 pubmed publisher
Weisberg S, Carpenter D, Chait M, Dogra P, Gartrell Corrado R, Chen A, et al. Tissue-Resident Memory T Cells Mediate Immune Homeostasis in the Human Pancreas through the PD-1/PD-L1 Pathway. Cell Rep. 2019;29:3916-3932.e5 pubmed publisher
Cash J, Bena S, Headland S, McArthur S, Brancaleone V, Perretti M. Chemerin15 inhibits neutrophil-mediated vascular inflammation and myocardial ischemia-reperfusion injury through ChemR23. EMBO Rep. 2013;14:999-1007 pubmed publisher
Burgess M, Gill D, Singhania R, Cheung C, Chambers L, Renyolds B, et al. CD62L as a therapeutic target in chronic lymphocytic leukemia. Clin Cancer Res. 2013;19:5675-85 pubmed publisher
Shi C, Hohl T, Leiner I, Equinda M, Fan X, Pamer E. Ly6G+ neutrophils are dispensable for defense against systemic Listeria monocytogenes infection. J Immunol. 2011;187:5293-8 pubmed publisher
Charles N, Hardwick D, Daugas E, Illei G, Rivera J. Basophils and the T helper 2 environment can promote the development of lupus nephritis. Nat Med. 2010;16:701-7 pubmed publisher
Kmieciak M, Gowda M, Graham L, Godder K, Bear H, Marincola F, et al. Human T cells express CD25 and Foxp3 upon activation and exhibit effector/memory phenotypes without any regulatory/suppressor function. J Transl Med. 2009;7:89 pubmed publisher
Tamassia N, Le Moigne V, Rossato M, Donini M, McCartney S, Calzetti F, et al. Activation of an immunoregulatory and antiviral gene expression program in poly(I:C)-transfected human neutrophils. J Immunol. 2008;181:6563-73 pubmed
Thakral D, Dobbins J, Devine L, Kavathas P. Differential expression of the human CD8beta splice variants and regulation of the M-2 isoform by ubiquitination. J Immunol. 2008;180:7431-42 pubmed
product information
Antigen :
CD62L
Apps. Abbrev. :
FC
Cat # :
304830
Clone :
DREG-56
Item :
Brilliant Violet 785™ anti-human CD62L
Isotype :
Mouse IgG1, κ
Other Names :
L-selectin, LECAM-1, LAM-1, Leu-8, TQ-1
Size :
100 tests
Price (USD) :
418 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
BV785
Immunogen :
Concentrated supernatant from PMA-activated human peripheral blood leukocytes
Application Notes :
Additional reported applications (for the relevant formats) include: Western blotting^2,3,9 and in vitro blocking of lymphocytes binding to high endothelial venules (HEV)^2. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. Nos. 304853-304858).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA