product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Brilliant Violet 421™ anti-human CD62L
catalog :
304828
quantity :
100 tests
price :
381 USD
clonality :
monoclonal
host :
mouse
conjugate :
BV421
clone name :
DREG-56
reactivity :
human
application :
flow cytometry
more info or order :
citations: 20
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human
Jitschin R, Braun M, Büttner M, Dettmer Wilde K, Bricks J, Berger J, et al. CLL-cells induce IDOhi CD14+HLA-DRlo myeloid-derived suppressor cells that inhibit T-cell responses and promote TRegs. Blood. 2014;124:750-60 pubmed publisher
Wu L, Brzostek J, Sakthi Vale P, Wei Q, Koh C, Ong J, et al. CD28-CAR-T cell activation through FYN kinase signaling rather than LCK enhances therapeutic performance. Cell Rep Med. 2023;4:100917 pubmed publisher
Wilson T, Kim H, Chou C, Langfitt D, Mettelman R, Minervina A, et al. Common trajectories of highly effective CD19-specific CAR T cells identified by endogenous T cell receptor lineages. Cancer Discov. 2022;: pubmed publisher
Kim S, Vale N, Zacharakis N, Krishna S, Yu Z, Gasmi B, et al. Adoptive Cellular Therapy with Autologous Tumor-Infiltrating Lymphocytes and T-cell Receptor-Engineered T Cells Targeting Common p53 Neoantigens in Human Solid Tumors. Cancer Immunol Res. 2022;10:932-946 pubmed publisher
Ando M, Kondo T, Tomisato W, Ito M, Shichino S, Srirat T, et al. Rejuvenating Effector/Exhausted CAR T Cells to Stem Cell Memory-Like CAR T Cells By Resting Them in the Presence of CXCL12 and the NOTCH Ligand. Cancer Res Commun. 2021;1:41-55 pubmed publisher
Gussarow D, Bonifacius A, Cossmann A, Stankov M, Mausberg P, Tischer Zimmermann S, et al. Long-Lasting Immunity Against SARS-CoV-2: Dream or Reality?. Front Med (Lausanne). 2021;8:770381 pubmed publisher
Krampert L, Bauer K, Ebner S, Neubert P, Ossner T, Weigert A, et al. High Na+ Environments Impair Phagocyte Oxidase-Dependent Antibacterial Activity of Neutrophils. Front Immunol. 2021;12:712948 pubmed publisher
Bonifacius A, Tischer Zimmermann S, Dragon A, Gussarow D, Vogel A, Krettek U, et al. COVID-19 immune signatures reveal stable antiviral T cell function despite declining humoral responses. Immunity. 2021;54:340-354.e6 pubmed publisher
Kim Y, Kobayashi E, Suehara Y, Ito A, Kubota D, Tanzawa Y, et al. Immunological status of peripheral blood is associated with prognosis in patients with bone and soft-tissue sarcoma. Oncol Lett. 2021;21:212 pubmed publisher
Kalina T, Bakardjieva M, Blom M, Perez Andres M, Barendregt B, Kanderová V, et al. EuroFlow Standardized Approach to Diagnostic Immunopheneotyping of Severe PID in Newborns and Young Children. Front Immunol. 2020;11:371 pubmed publisher
van Dongen J, van der Burg M, Kalina T, Perez Andres M, Mejstrikova E, Vlkova M, et al. EuroFlow-Based Flowcytometric Diagnostic Screening and Classification of Primary Immunodeficiencies of the Lymphoid System. Front Immunol. 2019;10:1271 pubmed publisher
Montel Hagen A, Seet C, Li S, Chick B, Zhu Y, Chang P, et al. Organoid-Induced Differentiation of Conventional T Cells from Human Pluripotent Stem Cells. Cell Stem Cell. 2019;24:376-389.e8 pubmed publisher
Sung J, Patel S, Clohosey M, Roesch L, Tripic T, Kuruc J, et al. HIV-Specific, Ex Vivo Expanded T Cell Therapy: Feasibility, Safety, and Efficacy in ART-Suppressed HIV-Infected Individuals. Mol Ther. 2018;26:2496-2506 pubmed publisher
Cash J, Bena S, Headland S, McArthur S, Brancaleone V, Perretti M. Chemerin15 inhibits neutrophil-mediated vascular inflammation and myocardial ischemia-reperfusion injury through ChemR23. EMBO Rep. 2013;14:999-1007 pubmed publisher
Burgess M, Gill D, Singhania R, Cheung C, Chambers L, Renyolds B, et al. CD62L as a therapeutic target in chronic lymphocytic leukemia. Clin Cancer Res. 2013;19:5675-85 pubmed publisher
Shi C, Hohl T, Leiner I, Equinda M, Fan X, Pamer E. Ly6G+ neutrophils are dispensable for defense against systemic Listeria monocytogenes infection. J Immunol. 2011;187:5293-8 pubmed publisher
Charles N, Hardwick D, Daugas E, Illei G, Rivera J. Basophils and the T helper 2 environment can promote the development of lupus nephritis. Nat Med. 2010;16:701-7 pubmed publisher
Kmieciak M, Gowda M, Graham L, Godder K, Bear H, Marincola F, et al. Human T cells express CD25 and Foxp3 upon activation and exhibit effector/memory phenotypes without any regulatory/suppressor function. J Transl Med. 2009;7:89 pubmed publisher
Tamassia N, Le Moigne V, Rossato M, Donini M, McCartney S, Calzetti F, et al. Activation of an immunoregulatory and antiviral gene expression program in poly(I:C)-transfected human neutrophils. J Immunol. 2008;181:6563-73 pubmed
Thakral D, Dobbins J, Devine L, Kavathas P. Differential expression of the human CD8beta splice variants and regulation of the M-2 isoform by ubiquitination. J Immunol. 2008;180:7431-42 pubmed
product information
Antigen :
CD62L
Apps. Abbrev. :
FC
Cat # :
304828
Clone :
DREG-56
Item :
Brilliant Violet 421™ anti-human CD62L
Isotype :
Mouse IgG1, κ
Other Names :
L-selectin, LECAM-1, LAM-1, Leu-8, TQ-1
Size :
100 tests
Price (USD) :
381 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
BV421
Immunogen :
Concentrated supernatant from PMA-activated human peripheral blood leukocytes
Application Notes :
Additional reported applications (for the relevant formats) include: Western blotting^2,3,9 and in vitro blocking of lymphocytes binding to high endothelial venules (HEV)^2. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. Nos. 304853-304858).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA