product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PE/Cyanine7 anti-human CD62L
catalog :
304821
quantity :
25 tests
price :
153 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE/Cy7
clone name :
DREG-56
reactivity :
human
application :
flow cytometry
more info or order :
citations: 28
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 2
Krogh Nielsen M, Hector S, Allen K, Subhi Y, Sørensen T. Altered activation state of circulating neutrophils in patients with neovascular age-related macular degeneration. Immun Ageing. 2017;14:18 pubmed publisher
  • flow cytometry; human
Konadu K, Chu J, Huang M, Amancha P, Armstrong W, Powell M, et al. Association of Cytokines With Exosomes in the Plasma of HIV-1-Seropositive Individuals. J Infect Dis. 2015;211:1712-6 pubmed publisher
Graciliano N, Ten xf3 rio M, Fragoso M, Moura F, Botelho R, Tanabe E, et al. The impact on colostrum oxidative stress, cytokines, and immune cells composition after SARS-CoV-2 infection during pregnancy. Front Immunol. 2022;13:1031248 pubmed publisher
Theobald S, Simonis A, Mudler J, G xf6 bel U, Acton R, Kohlhas V, et al. Spleen tyrosine kinase mediates innate and adaptive immune crosstalk in SARS-CoV-2 mRNA vaccination. EMBO Mol Med. 2022;14:e15888 pubmed publisher
Ye L, Park J, Peng L, Yang Q, Chow R, Lam S, et al. A genome-scale gain-of-function CRISPR screen in CD8 T cells identifies proline metabolism as a means to enhance CAR-T therapy. Cell Metab. 2022;34:595-614.e14 pubmed publisher
Li Y, Zhou Y, Kim Y, Zhu Y, Ma F, Yu J, et al. Development of allogeneic HSC-engineered iNKT cells for off-the-shelf cancer immunotherapy. Cell Rep Med. 2021;2:100449 pubmed publisher
Zhou Y, Li Y, Zeng S, Yang L. Methods for Studying Mouse and Human Invariant Natural Killer T Cells. Methods Mol Biol. 2021;2388:35-57 pubmed publisher
Liao H, Han M, Cheng W, Zhang C, Li H, Li M, et al. Decidual-derived RANKL facilitates macrophages accumulation and residence at the maternal-fetal interface in human early pregnancy. Am J Reprod Immunol. 2021;86:e13406 pubmed publisher
Shi Z, Qiu Y, Zhao Z, Wen D, Chen H, Du Q, et al. CD8+ T cell subpopulations and pro-inflammatory cytokines in neuromyelitis optica spectrum disorder. Ann Clin Transl Neurol. 2021;8:43-53 pubmed publisher
Moorlag S, Rodriguez Rosales Y, Gillard J, Fanucchi S, Theunissen K, Novakovic B, et al. BCG Vaccination Induces Long-Term Functional Reprogramming of Human Neutrophils. Cell Rep. 2020;33:108387 pubmed publisher
Giamarellos Bourboulis E, Tsilika M, Moorlag S, Antonakos N, Kotsaki A, Domínguez Andrés J, et al. Activate: Randomized Clinical Trial of BCG Vaccination against Infection in the Elderly. Cell. 2020;183:315-323.e9 pubmed publisher
Toews K, Grunewald L, Schwiebert S, Klaus A, Winkler A, Ali S, et al. Central memory phenotype drives success of checkpoint inhibition in combination with CAR T cells. Mol Carcinog. 2020;59:724-735 pubmed publisher
Chabi S, Uzan B, Naguibneva I, Rucci J, Fahy L, Calvo J, et al. Hypoxia Regulates Lymphoid Development of Human Hematopoietic Progenitors. Cell Rep. 2019;29:2307-2320.e6 pubmed publisher
Zou F, Lu L, Liu J, Xia B, Zhang W, Hu Q, et al. Engineered triple inhibitory receptor resistance improves anti-tumor CAR-T cell performance via CD56. Nat Commun. 2019;10:4109 pubmed publisher
Zhu Y, Smith D, Zhou Y, Li Y, Yu J, Lee D, et al. Development of Hematopoietic Stem Cell-Engineered Invariant Natural Killer T Cell Therapy for Cancer. Cell Stem Cell. 2019;25:542-557.e9 pubmed publisher
Das R, Vernau L, Grupp S, Barrett D. Naïve T-cell Deficits at Diagnosis and after Chemotherapy Impair Cell Therapy Potential in Pediatric Cancers. Cancer Discov. 2019;9:492-499 pubmed publisher
Kim C, Hu B, Jadhav R, Jin J, Zhang H, Cavanagh M, et al. Activation of miR-21-Regulated Pathways in Immune Aging Selects against Signatures Characteristic of Memory T Cells. Cell Rep. 2018;25:2148-2162.e5 pubmed publisher
Singh N, Perazzelli J, Grupp S, Barrett D. Early memory phenotypes drive T cell proliferation in patients with pediatric malignancies. Sci Transl Med. 2016;8:320ra3 pubmed publisher
Crompton J, Sukumar M, Roychoudhuri R, Clever D, Gros A, Eil R, et al. Akt inhibition enhances expansion of potent tumor-specific lymphocytes with memory cell characteristics. Cancer Res. 2015;75:296-305 pubmed publisher
Hu N, Mora Jensen H, Theilgaard Monch K, Doornbos van der Meer B, Huitema M, Stegeman C, et al. Differential expression of granulopoiesis related genes in neutrophil subsets distinguished by membrane expression of CD177. PLoS ONE. 2014;9:e99671 pubmed publisher
Cash J, Bena S, Headland S, McArthur S, Brancaleone V, Perretti M. Chemerin15 inhibits neutrophil-mediated vascular inflammation and myocardial ischemia-reperfusion injury through ChemR23. EMBO Rep. 2013;14:999-1007 pubmed publisher
Burgess M, Gill D, Singhania R, Cheung C, Chambers L, Renyolds B, et al. CD62L as a therapeutic target in chronic lymphocytic leukemia. Clin Cancer Res. 2013;19:5675-85 pubmed publisher
Shi C, Hohl T, Leiner I, Equinda M, Fan X, Pamer E. Ly6G+ neutrophils are dispensable for defense against systemic Listeria monocytogenes infection. J Immunol. 2011;187:5293-8 pubmed publisher
Veerapathran A, Pidala J, Beato F, Yu X, Anasetti C. Ex vivo expansion of human Tregs specific for alloantigens presented directly or indirectly. Blood. 2011;118:5671-80 pubmed publisher
Charles N, Hardwick D, Daugas E, Illei G, Rivera J. Basophils and the T helper 2 environment can promote the development of lupus nephritis. Nat Med. 2010;16:701-7 pubmed publisher
Kmieciak M, Gowda M, Graham L, Godder K, Bear H, Marincola F, et al. Human T cells express CD25 and Foxp3 upon activation and exhibit effector/memory phenotypes without any regulatory/suppressor function. J Transl Med. 2009;7:89 pubmed publisher
Tamassia N, Le Moigne V, Rossato M, Donini M, McCartney S, Calzetti F, et al. Activation of an immunoregulatory and antiviral gene expression program in poly(I:C)-transfected human neutrophils. J Immunol. 2008;181:6563-73 pubmed
Thakral D, Dobbins J, Devine L, Kavathas P. Differential expression of the human CD8beta splice variants and regulation of the M-2 isoform by ubiquitination. J Immunol. 2008;180:7431-42 pubmed
product information
Antigen :
CD62L
Apps. Abbrev. :
FC
Cat # :
304821
Clone :
DREG-56
Item :
PE/Cyanine7 anti-human CD62L
Isotype :
Mouse IgG1, κ
Other Names :
L-selectin, LECAM-1, LAM-1, Leu-8, TQ-1
Size :
25 tests
Price (USD) :
153 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PE_CYANINE7
Immunogen :
Concentrated supernatant from PMA-activated human peripheral blood leukocytes
Application Notes :
Additional reported applications (for the relevant formats) include: Western blotting^2,3,9 and in vitro blocking of lymphocytes binding to high endothelial venules (HEV)^2. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. Nos. 304853-304858).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA