product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Purified anti-human CD51/61
catalog :
304402
quantity :
100 μg
price :
102 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
23C6
reactivity :
human
application :
immunocytochemistry, neutralization, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 6
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human
Hui T, Sørensen E, Rittling S. Osteopontin binding to the alpha 4 integrin requires highest affinity integrin conformation, but is independent of post-translational modifications of osteopontin. Matrix Biol. 2015;41:19-25 pubmed publisher
Kariya Y, Oyama M, Suzuki T, Kariya Y. αvβ3 Integrin induces partial EMT independent of TGF-β signaling. Commun Biol. 2021;4:490 pubmed publisher
Mousset C, Hobo W, Ji Y, Fredrix H, De Giorgi V, Allison R, et al. Ex vivo AKT-inhibition facilitates generation of polyfunctional stem cell memory-like CD8+ T cells for adoptive immunotherapy. Oncoimmunology. 2018;7:e1488565 pubmed publisher
Oyama M, Kariya Y, Kariya Y, Matsumoto K, Kanno M, Yamaguchi Y, et al. Biological role of site-specific O-glycosylation in cell adhesion activity and phosphorylation of osteopontin. Biochem J. 2018;475:1583-1595 pubmed publisher
Sivasubramaniyan K, Harichandan A, Schilbach K, Mack A, Bedke J, Stenzl A, et al. Expression of stage-specific embryonic antigen-4 (SSEA-4) defines spontaneous loss of epithelial phenotype in human solid tumor cells. Glycobiology. 2015;25:902-17 pubmed publisher
Barua A, Bitterman P, Bahr J, Bradaric M, Hales D, Luborsky J, et al. Detection of tumor-associated neoangiogenesis by Doppler ultrasonography during early-stage ovarian cancer in laying hens: a preclinical model of human spontaneous ovarian cancer. J Ultrasound Med. 2010;29:173-82 pubmed
product information
Antigen :
CD51 CD61
Apps. Abbrev. :
FC, ICC, IHC-F, IP, Block
Cat # :
304402
Clone :
23C6
Item :
Purified anti-human CD51/61
Isotype :
Mouse IgG1, κ
Other Names :
Vitronectin receptor, Integrin αV/β3, ITGAV, ITGB3
Size :
100 μg
Price (USD) :
102 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PURE
Application Notes :
Additional reported applications (for the relevant formats) include: immunoprecipitation^5, immunohistochemical staining of acetone-fixed frozen tissue sections^5, immunofluorescence microscopy^5, and blocking of cell adhesion^4,6. The LEAF™ Purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 304414).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA