product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
APC anti-human CD49d
catalog :
304307
quantity :
25 tests
price :
138 USD
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
9F10
reactivity :
human, rhesus macaque
application :
flow cytometry
more info or order :
citations: 21
Reference
Paris O, Mennechet F, Kremer E. Human innate lymphoid cell activation by adenoviruses is modified by host defense proteins and neutralizing antibodies. Front Immunol. 2022;13:975910 pubmed publisher
Zheng Y, Sefik E, Astle J, Karatepe K, xd6 z H, Solis A, et al. Human neutrophil development and functionality are enabled in a humanized mouse model. Proc Natl Acad Sci U S A. 2022;119:e2121077119 pubmed publisher
Maas R, Soukup K, Klemm F, Kornete M, Bowman R, Bedel R, et al. An integrated pipeline for comprehensive analysis of immune cells in human brain tumor clinical samples. Nat Protoc. 2021;16:4692-4721 pubmed publisher
Caielli S, Cardenas J, de Jesus A, Baisch J, Walters L, Blanck J, et al. Erythroid mitochondrial retention triggers myeloid-dependent type I interferon in human SLE. Cell. 2021;184:4464-4479.e19 pubmed publisher
Port J, Wozniak D, Oestereich L, Pallasch E, Becker Ziaja B, M xfc ller J, et al. Severe Human Lassa Fever Is Characterized by Nonspecific T-Cell Activation and Lymphocyte Homing to Inflamed Tissues. J Virol. 2020;94: pubmed publisher
Klemm F, Maas R, Bowman R, Kornete M, Soukup K, Nassiri S, et al. Interrogation of the Microenvironmental Landscape in Brain Tumors Reveals Disease-Specific Alterations of Immune Cells. Cell. 2020;181:1643-1660.e17 pubmed publisher
Deng Y, Herbert J, Robinson E, Ren L, Smyth R, Smith C. Neutrophil-Airway Epithelial Interactions Result in Increased Epithelial Damage and Viral Clearance during Respiratory Syncytial Virus Infection. J Virol. 2020;94: pubmed publisher
Manukyan G, Martirosyan A, Slavik L, Margaryan S, Ulehlova J, Mikulkova Z, et al. Anti-domain 1 β2 glycoprotein antibodies increase expression of tissue factor on monocytes and activate NK Cells and CD8+ cells in vitro. Auto Immun Highlights. 2020;11:5 pubmed publisher
Miller L, Cossette C, Chourey S, Ye Q, Reddy C, Rokach J, et al. Inhibition of allergen-induced dermal eosinophilia by an oxoeicosanoid receptor antagonist in non-human primates. Br J Pharmacol. 2020;177:360-371 pubmed publisher
Ludwig L, Lareau C, Bao E, Nandakumar S, Muus C, Ulirsch J, et al. Transcriptional States and Chromatin Accessibility Underlying Human Erythropoiesis. Cell Rep. 2019;27:3228-3240.e7 pubmed publisher
He W, Holtkamp S, Hergenhan S, Kraus K, De Juan A, Weber J, et al. Circadian Expression of Migratory Factors Establishes Lineage-Specific Signatures that Guide the Homing of Leukocyte Subsets to Tissues. Immunity. 2018;49:1175-1190.e7 pubmed publisher
Bouafia A, Lofek S, Bruneau J, Chentout L, Lamrini H, Trinquand A, et al. Loss of ARHGEF1 causes a human primary antibody deficiency. J Clin Invest. 2019;129:1047-1060 pubmed publisher
Shibata S, Hayashi R, Okubo T, Kudo Y, Katayama T, Ishikawa Y, et al. Selective Laminin-Directed Differentiation of Human Induced Pluripotent Stem Cells into Distinct Ocular Lineages. Cell Rep. 2018;25:1668-1679.e5 pubmed publisher
Zhu Y, Padgett L, Dinh H, Marcovecchio P, Blatchley A, Wu R, et al. Identification of an Early Unipotent Neutrophil Progenitor with Pro-tumoral Activity in Mouse and Human Bone Marrow. Cell Rep. 2018;24:2329-2341.e8 pubmed publisher
Shlamkovich T, Aharon L, Koslawsky D, Einav Y, Papo N. Targeting the Tie2-αvβ3 integrin axis with bi-specific reagents for the inhibition of angiogenesis. BMC Biol. 2018;16:92 pubmed publisher
Deng Y, Herbert J, Smith C, Smyth R. An in vitro transepithelial migration assay to evaluate the role of neutrophils in Respiratory Syncytial Virus (RSV) induced epithelial damage. Sci Rep. 2018;8:6777 pubmed publisher
Alhaj Hussen K, Vu Manh T, Guimiot F, Nelson E, Chabaane E, Delord M, et al. Molecular and Functional Characterization of Lymphoid Progenitor Subsets Reveals a Bipartite Architecture of Human Lymphopoiesis. Immunity. 2017;47:680-696.e8 pubmed publisher
Genbacev O, Larocque N, Ona K, Prakobphol A, Garrido Gomez T, Kapidzic M, et al. Integrin ?4-positive human trophoblast progenitors: functional characterization and transcriptional regulation. Hum Reprod. 2016;31:1300-14 pubmed publisher
Cossette C, Gravel S, Reddy C, Gore V, Chourey S, Ye Q, et al. Biosynthesis and actions of 5-oxoeicosatetraenoic acid (5-oxo-ETE) on feline granulocytes. Biochem Pharmacol. 2015;96:247-55 pubmed publisher
Rullo J, Becker H, Hyduk S, Wong J, Digby G, Arora P, et al. Actin polymerization stabilizes ?4?1 integrin anchors that mediate monocyte adhesion. J Cell Biol. 2012;197:115-29 pubmed publisher
Palacios F, Moreno P, Morande P, Abreu C, Correa A, Porro V, et al. High expression of AID and active class switch recombination might account for a more aggressive disease in unmutated CLL patients: link with an activated microenvironment in CLL disease. Blood. 2010;115:4488-96 pubmed publisher
product information
Antigen :
CD49d
Apps. Abbrev. :
FC
Cat # :
304307
Clone :
9F10
Item :
APC anti-human CD49d
Isotype :
Mouse IgG1, κ
Other Names :
VLA-4 α chain, α4 integrin, Integrin α4 chain, ITGA4
Size :
25 tests
Price (USD) :
138 USD
Reactivity :
Human, Cynomolgus, Rhesus
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
APC
Application Notes :
Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections, and in vitro T cell costimulation^2,3. The Ultra-LEAF™ Purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 304339 and 304340).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA