product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Purified anti-human CD49d
catalog :
304302
quantity :
100 μg
price :
102 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
9F10
reactivity :
human, dogs, rhesus macaque
application :
flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 24
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; 1:100; loading ...; fig 6a
Benkhoucha M, Tran N, Breville G, Senoner I, Bradfield P, Papayannopoulou T, et al. CD4+c-Met+Itgα4+ T cell subset promotes murine neuroinflammation. J Neuroinflammation. 2022;19:103 pubmed publisher
  • flow cytometry; human; loading ...; fig 1a
Olin A, Henckel E, Chen Y, Lakshmikanth T, Pou C, Mikes J, et al. Stereotypic Immune System Development in Newborn Children. Cell. 2018;174:1277-1292.e14 pubmed publisher
  • flow cytometry; dogs; loading ...; fig 4c
McGill J, Wang Y, Ganta C, Boorgula G, Ganta R. Antigen-Specific CD4+CD8+ Double-Positive T Cells Are Increased in the Blood and Spleen During Ehrlichia chaffeensis Infection in the Canine Host. Front Immunol. 2018;9:1585 pubmed publisher
  • flow cytometry; human
Rao D, Gurish M, Marshall J, Slowikowski K, Fonseka C, Liu Y, et al. Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis. Nature. 2017;542:110-114 pubmed publisher
  • flow cytometry; human; loading ...; fig 2b
Chorzalska A, Kim J, Roder K, Tepper A, Ahsan N, Rao R, et al. Long-Term Exposure to Imatinib Mesylate Downregulates Hippo Pathway and Activates YAP in a Model of Chronic Myelogenous Leukemia. Stem Cells Dev. 2017;26:656-677 pubmed publisher
  • flow cytometry; rhesus macaque; 1 ug/ml; loading ...
Roberts E, Carnathan D, Li H, Shaw G, Silvestri G, Betts M. Collapse of Cytolytic Potential in SIV-Specific CD8+ T Cells Following Acute SIV Infection in Rhesus Macaques. PLoS Pathog. 2016;12:e1006135 pubmed publisher
  • flow cytometry; human; fig 4
Liu C, LeClair P, Monajemi M, Sly L, Reid G, Lim C. α-Integrin expression and function modulates presentation of cell surface calreticulin. Cell Death Dis. 2016;7:e2268 pubmed publisher
  • flow cytometry; human; fig 7
Schneider Hohendorf T, Rossaint J, Mohan H, Böning D, Breuer J, Kuhlmann T, et al. VLA-4 blockade promotes differential routes into human CNS involving PSGL-1 rolling of T cells and MCAM-adhesion of TH17 cells. J Exp Med. 2014;211:1833-46 pubmed publisher
Moon J, Younis S, Ramadoss N, Iyer R, Sheth K, Sharpe O, et al. Cytotoxic CD8+ T cells target citrullinated antigens in rheumatoid arthritis. Nat Commun. 2023;14:319 pubmed publisher
Rosa Duque J, Wang X, Leung D, Cheng S, Cohen C, Mu X, et al. Immunogenicity and reactogenicity of SARS-CoV-2 vaccines BNT162b2 and CoronaVac in healthy adolescents. Nat Commun. 2022;13:3700 pubmed publisher
Vivanco Gonzalez N, Oliveria J, Tebaykin D, Ivison G, Mukai K, Tsai M, et al. An optimized protocol for phenotyping human granulocytes by mass cytometry. STAR Protoc. 2022;3:101280 pubmed publisher
Peng Q, Zhou R, Wang Y, Zhao M, Liu N, Li S, et al. Waning immune responses against SARS-CoV-2 variants of concern among vaccinees in Hong Kong. EBioMedicine. 2022;77:103904 pubmed publisher
Pymm P, Tenzer S, Wee E, Weimershaus M, Burgevin A, Kollnberger S, et al. Epitope length variants balance protective immune responses and viral escape in HIV-1 infection. Cell Rep. 2022;38:110449 pubmed publisher
Sandborn W, Mattheakis L, Modi N, Pugatch D, Bressler B, Lee S, et al. PTG-100, an Oral α4β7 Antagonist Peptide: Preclinical Development and Phase 1 and 2a Studies in Ulcerative Colitis. Gastroenterology. 2021;161:1853-1864.e10 pubmed publisher
Niu M, Wong Y, Wang H, Li X, Chan C, Zhang Q, et al. Tandem bispecific antibody prevents pathogenic SHIVSF162P3CN infection and disease progression. Cell Rep. 2021;36:109611 pubmed publisher
Zabaleta N, Dai W, Bhatt U, Hérate C, Maisonnasse P, Chichester J, et al. An AAV-based, room-temperature-stable, single-dose COVID-19 vaccine provides durable immunogenicity and protection in non-human primates. Cell Host Microbe. 2021;29:1437-1453.e8 pubmed publisher
Gogolou A, Frith T, Tsakiridis A. Generating Enteric Nervous System Progenitors from Human Pluripotent Stem Cells. Curr Protoc. 2021;1:e137 pubmed publisher
Kaufmann M, Evans H, Schaupp A, Engler J, Kaur G, Willing A, et al. Identifying CNS-colonizing T cells as potential therapeutic targets to prevent progression of multiple sclerosis. Med (N Y). 2021;2:296-312.e8 pubmed publisher
Zhou R, To K, Wong Y, Liu L, Zhou B, Li X, et al. Acute SARS-CoV-2 Infection Impairs Dendritic Cell and T Cell Responses. Immunity. 2020;53:864-877.e5 pubmed publisher
Pomplun N, Vosler L, Weisgrau K, Furlott J, Weiler A, Abdelaal H, et al. Immunophenotyping of Rhesus CMV-Specific CD8 T-Cell Populations. Cytometry A. 2021;99:278-288 pubmed publisher
O Boyle K, Ohtani T, Manne S, Bengsch B, Henrickson S, Wherry E, et al. Exploration of T-Cell Diversity Using Mass Cytometry. Methods Mol Biol. 2020;2111:1-20 pubmed publisher
Chng M, Lim M, Rouers A, Becht E, Lee B, Macary P, et al. Large-Scale HLA Tetramer Tracking of T Cells during Dengue Infection Reveals Broad Acute Activation and Differentiation into Two Memory Cell Fates. Immunity. 2019;51:1119-1135.e5 pubmed publisher
Evrard M, Kwok I, Chong S, Teng K, Becht E, Chen J, et al. Developmental Analysis of Bone Marrow Neutrophils Reveals Populations Specialized in Expansion, Trafficking, and Effector Functions. Immunity. 2018;48:364-379.e8 pubmed publisher
Singh A, Novakova L, Axelsson M, Malmeström C, Zetterberg H, Lycke J, et al. High Interferon-γ Uniquely in Vδ1 T Cells Correlates with Markers of Inflammation and Axonal Damage in Early Multiple Sclerosis. Front Immunol. 2017;8:260 pubmed publisher
product information
Antigen :
CD49d
Apps. Abbrev. :
FC, IHC-F, Costim
Cat # :
304302
Clone :
9F10
Item :
Purified anti-human CD49d
Isotype :
Mouse IgG1, κ
Other Names :
VLA-4 α chain, α4 integrin, Integrin α4 chain, ITGA4
Size :
100 μg
Price (USD) :
102 USD
Reactivity :
Human, Cynomolgus, Rhesus
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PURE
Application Notes :
Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections, and in vitro T cell costimulation^2,3. The Ultra-LEAF™ Purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 304339 and 304340).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA