This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Pacific Blue™ anti-human CD45RO
catalog :
304215
quantity :
25 μg
price :
116 USD
clonality :
monoclonal
host :
mouse
conjugate :
Pacific Blue
clone name :
UCHL1

The same clone is also sold as:
reactivity :
human, chimpanzee
application :
flow cytometry
citations: 16
Reference
Zhu Y, Smith D, Zhou Y, Li Y, Yu J, Lee D, et al. Development of Hematopoietic Stem Cell-Engineered Invariant Natural Killer T Cell Therapy for Cancer. Cell Stem Cell. 2019;25:542-557.e9 pubmed publisher
Barman S, Kayama H, Okuzaki D, Ogino T, Osawa H, Matsuno H, et al. Identification of a human intestinal myeloid cell subset that regulates gut homeostasis. Int Immunol. 2016;28:533-545 pubmed
Rueda C, Wells C, Gisslen T, Jobe A, Kallapur S, Chougnet C. Effect of chorioamnionitis on regulatory T cells in moderate/late preterm neonates. Hum Immunol. 2015;76:65-73 pubmed publisher
Trinité B, Chan C, Lee C, Mahajan S, Luo Y, Muesing M, et al. Suppression of Foxo1 activity and down-modulation of CD62L (L-selectin) in HIV-1 infected resting CD4 T cells. PLoS ONE. 2014;9:e110719 pubmed publisher
Zhou A, Kozhaya L, Fujii H, Unutmaz D. GARP-TGF-? complexes negatively regulate regulatory T cell development and maintenance of peripheral CD4+ T cells in vivo. J Immunol. 2013;190:5057-64 pubmed publisher
Long H, Chagoury O, Leese A, Ryan G, James E, Morton L, et al. MHC II tetramers visualize human CD4+ T cell responses to Epstein-Barr virus infection and demonstrate atypical kinetics of the nuclear antigen EBNA1 response. J Exp Med. 2013;210:933-49 pubmed publisher
Shen H, Zhang W, Abraham C, Cho J. Age and CD161 expression contribute to inter-individual variation in interleukin-23 response in CD8+ memory human T cells. PLoS ONE. 2013;8:e57746 pubmed publisher
Di Meglio P, Di Cesare A, Laggner U, Chu C, Napolitano L, Villanova F, et al. The IL23R R381Q gene variant protects against immune-mediated diseases by impairing IL-23-induced Th17 effector response in humans. PLoS ONE. 2011;6:e17160 pubmed publisher
Weiss L, Letimier F, Carriere M, Maiella S, Donkova Petrini V, Targat B, et al. In vivo expansion of naive and activated CD4+CD25+FOXP3+ regulatory T cell populations in interleukin-2-treated HIV patients. Proc Natl Acad Sci U S A. 2010;107:10632-7 pubmed publisher
Baba N, Rubio M, Sarfati M. Interplay between CD45RA+ regulatory T cells and TNF-alpha in the regulation of human Th17 differentiation. Int Immunol. 2010;22:237-44 pubmed publisher
Mercer F, Kozhaya L, Unutmaz D. Expression and function of TNF and IL-1 receptors on human regulatory T cells. PLoS ONE. 2010;5:e8639 pubmed publisher
Mozaffarian N, Wiedeman A, Stevens A. Active systemic lupus erythematosus is associated with failure of antigen-presenting cells to express programmed death ligand-1. Rheumatology (Oxford). 2008;47:1335-41 pubmed publisher
Thakral D, Dobbins J, Devine L, Kavathas P. Differential expression of the human CD8beta splice variants and regulation of the M-2 isoform by ubiquitination. J Immunol. 2008;180:7431-42 pubmed
Wu Y, Tsai H, Lin W, Hsu P, Shun C, Wu M, et al. Upregulation of CCL20 and recruitment of CCR6+ gastric infiltrating lymphocytes in Helicobacter pylori gastritis. Infect Immun. 2007;75:4357-63 pubmed
Roque S, Nobrega C, Appelberg R, Correia Neves M. IL-10 underlies distinct susceptibility of BALB/c and C57BL/6 mice to Mycobacterium avium infection and influences efficacy of antibiotic therapy. J Immunol. 2007;178:8028-35 pubmed
Schmidt C, Giese T, Ludwig B, Mueller Molaian I, Marth T, Zeuzem S, et al. Expression of interleukin-12-related cytokine transcripts in inflammatory bowel disease: elevated interleukin-23p19 and interleukin-27p28 in Crohn's disease but not in ulcerative colitis. Inflamm Bowel Dis. 2005;11:16-23 pubmed
product information
Antigen :
CD45RO
Apps. Abbrev. :
Flow Cytometry
Cat # :
304215
Clone :
UCHL1
Item :
Pacific Blue™ anti-human CD45RO
Isotype :
Mouse IgG2a, κ
Other Names :
CD45RO
Size :
25 μg
Price (USD) :
116 USD
Reactivity :
Human, Chimpanzee, Cynomolgus, Common Marmoset
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PB
Immunogen :
IL-2 dependent T cell line, CA1
Application Notes :
The UCHL1 antibody is commonly used in combination with antibodies against CD45RA to discern memory and naïve T cells. Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections 5 and formalin-fixed paraffin-embedded tissue sections 4 , Western blotting 2 , and immunoprecipitation 3 .
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA