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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PerCP/Cyanine5.5 anti-human CD45RA
catalog :
304121
quantity :
25 tests
price :
132 USD
clonality :
monoclonal
host :
mouse
conjugate :
PerCP/Cy5.5
clone name :
HI100
reactivity :
human
application :
flow cytometry
more info or order :
citations: 37
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human
Bendall S, Simonds E, Qiu P, Amir E, Krutzik P, Finck R, et al. Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. Science. 2011;332:687-96 pubmed publisher
Hasaart K, Manders F, Ubels J, Verheul M, van Roosmalen M, Groenen N, et al. Human induced pluripotent stem cells display a similar mutation burden as embryonic pluripotent cells in vivo. iScience. 2022;25:103736 pubmed publisher
Gray D, Santos J, Keir A, Villegas I, Maddock S, Trope E, et al. A comparison of DNA repair pathways to achieve a site-specific gene modification of the Bruton's tyrosine kinase gene. Mol Ther Nucleic Acids. 2022;27:505-516 pubmed publisher
Aalam F, Nabiee R, Castano J, Totonchy J. Analysis of KSHV B lymphocyte lineage tropism in human tonsil reveals efficient infection of CD138+ plasma cells. PLoS Pathog. 2020;16:e1008968 pubmed publisher
Saraiva D, Matias A, Braga S, Jacinto A, Cabral M. Establishment of a 3D Co-culture With MDA-MB-231 Breast Cancer Cell Line and Patient-Derived Immune Cells for Application in the Development of Immunotherapies. Front Oncol. 2020;10:1543 pubmed publisher
Cirovic B, de Bree L, Groh L, Blok B, Chan J, van der Velden W, et al. BCG Vaccination in Humans Elicits Trained Immunity via the Hematopoietic Progenitor Compartment. Cell Host Microbe. 2020;28:322-334.e5 pubmed publisher
Kang L, Tang X, Zhang J, Li M, Xu N, Qi W, et al. Interleukin-6-knockdown of chimeric antigen receptor-modified T cells significantly reduces IL-6 release from monocytes. Exp Hematol Oncol. 2020;9:11 pubmed publisher
Preglej T, Hamminger P, Luu M, Bulat T, Andersen L, Göschl L, et al. Histone deacetylases 1 and 2 restrain CD4+ cytotoxic T lymphocyte differentiation. JCI Insight. 2020;5: pubmed publisher
Freeman Z, Nirschl T, Hovelson D, Johnston R, Engelhardt J, Selby M, et al. A conserved intratumoral regulatory T cell signature identifies 4-1BB as a pan-cancer target. J Clin Invest. 2020;130:1405-1416 pubmed publisher
Rendeiro A, Krausgruber T, Fortelny N, Zhao F, Penz T, Farlik M, et al. Chromatin mapping and single-cell immune profiling define the temporal dynamics of ibrutinib response in CLL. Nat Commun. 2020;11:577 pubmed publisher
Zhu Y, Smith D, Zhou Y, Li Y, Yu J, Lee D, et al. Development of Hematopoietic Stem Cell-Engineered Invariant Natural Killer T Cell Therapy for Cancer. Cell Stem Cell. 2019;25:542-557.e9 pubmed publisher
Ickrath P, Scherzad A, Kleinsasser N, Ginzkey C, Hagen R, Hackenberg S. Influence of nasal polyp tissue on the differentiation and activation of T lymphocytes in a co-culture system. Biomed Rep. 2019;10:119-126 pubmed publisher
Montel Hagen A, Seet C, Li S, Chick B, Zhu Y, Chang P, et al. Organoid-Induced Differentiation of Conventional T Cells from Human Pluripotent Stem Cells. Cell Stem Cell. 2019;24:376-389.e8 pubmed publisher
Ueda M, El Jurdi N, Cooper B, Caimi P, Baer L, Kolk M, et al. Low-Dose Azacitidine with DNMT1 Level Monitoring to Treat Post-Transplantation Acute Myelogenous Leukemia or Myelodysplastic Syndrome Relapse. Biol Blood Marrow Transplant. 2019;25:1122-1127 pubmed publisher
Saraiva D, Jacinto A, Borralho P, Braga S, Cabral M. HLA-DR in Cytotoxic T Lymphocytes Predicts Breast Cancer Patients' Response to Neoadjuvant Chemotherapy. Front Immunol. 2018;9:2605 pubmed publisher
Liu Y, Lightfoot Y, Seto N, Carmona Rivera C, Moore E, Goel R, et al. Peptidylarginine deiminases 2 and 4 modulate innate and adaptive immune responses in TLR-7-dependent lupus. JCI Insight. 2018;3: pubmed publisher
Osorio F, Rosendahl Huber A, Oka R, Verheul M, Patel S, Hasaart K, et al. Somatic Mutations Reveal Lineage Relationships and Age-Related Mutagenesis in Human Hematopoiesis. Cell Rep. 2018;25:2308-2316.e4 pubmed publisher
Maehara T, Mattoo H, Mahajan V, Murphy S, Yuen G, Ishiguro N, et al. The expansion in lymphoid organs of IL-4+ BATF+ T follicular helper cells is linked to IgG4 class switching in vivo. Life Sci Alliance. 2018;1: pubmed publisher
Ickrath P, Kleinsasser N, Ding X, Ginzkey C, Beyersdorf N, Hagen R, et al. Accumulation of CD69+ tissue‑resident memory T cells in the nasal polyps of patients with chronic rhinosinusitis. Int J Mol Med. 2018;42:1116-1124 pubmed publisher
Idorn M, Olsen M, Halldórsdóttir H, Skadborg S, Pedersen M, Høgdall C, et al. Improved migration of tumor ascites lymphocytes to ovarian cancer microenvironment by CXCR2 transduction. Oncoimmunology. 2018;7:e1412029 pubmed publisher
Yamada E, Nakaoka S, Klein L, Reith E, Langer S, Hopfensperger K, et al. Human-Specific Adaptations in Vpu Conferring Anti-tetherin Activity Are Critical for Efficient Early HIV-1 Replication In Vivo. Cell Host Microbe. 2018;23:110-120.e7 pubmed publisher
Ogonek J, Verma K, Schultze Florey C, Varanasi P, Luther S, Schweier P, et al. Characterization of High-Avidity Cytomegalovirus-Specific T Cells with Differential Tetramer Binding Coappearing after Allogeneic Stem Cell Transplantation. J Immunol. 2017;199:792-805 pubmed publisher
Qu K, Zaba L, Satpathy A, Giresi P, Li R, Jin Y, et al. Chromatin Accessibility Landscape of Cutaneous T Cell Lymphoma and Dynamic Response to HDAC Inhibitors. Cancer Cell. 2017;32:27-41.e4 pubmed publisher
Eller M, Goonetilleke N, Tassaneetrithep B, Eller L, Costanzo M, Johnson S, et al. Expansion of Inefficient HIV-Specific CD8 T Cells during Acute Infection. J Virol. 2016;90:4005-4016 pubmed publisher
Han L, Yang J, Wang X, Wu Q, Yin S, Li Z, et al. The E3 deubiquitinase USP17 is a positive regulator of retinoic acid-related orphan nuclear receptor ?t (ROR?t) in Th17 cells. J Biol Chem. 2014;289:25546-55 pubmed publisher
Bunse C, Borchers S, Varanasi P, Tischer S, Figueiredo C, Immenschuh S, et al. Impaired functionality of antiviral T cells in G-CSF mobilized stem cell donors: implications for the selection of CTL donor. PLoS ONE. 2013;8:e77925 pubmed publisher
Bacher P, Schink C, Teutschbein J, Kniemeyer O, Assenmacher M, Brakhage A, et al. Antigen-reactive T cell enrichment for direct, high-resolution analysis of the human naive and memory Th cell repertoire. J Immunol. 2013;190:3967-76 pubmed publisher
Sammicheli S, Ruffin N, Lantto R, Vivar N, Chiodi F, Rethi B. IL-7 modulates B cells survival and activation by inducing BAFF and CD70 expression in T cells. J Autoimmun. 2012;38:304-14 pubmed publisher
Guerau de Arellano M, Smith K, Godlewski J, Liu Y, Winger R, Lawler S, et al. Micro-RNA dysregulation in multiple sclerosis favours pro-inflammatory T-cell-mediated autoimmunity. Brain. 2011;134:3578-89 pubmed publisher
Selleri S, Brigida I, Casiraghi M, Scaramuzza S, Cappelli B, Cassani B, et al. In vivo T-cell dynamics during immune reconstitution after hematopoietic stem cell gene therapy in adenosine deaminase severe combined immune deficiency. J Allergy Clin Immunol. 2011;127:1368-75.e8 pubmed publisher
Alanio C, Lemaitre F, Law H, Hasan M, Albert M. Enumeration of human antigen-specific naive CD8+ T cells reveals conserved precursor frequencies. Blood. 2010;115:3718-25 pubmed publisher
Iannello A, Boulassel M, Samarani S, Debbeche O, Tremblay C, Toma E, et al. Dynamics and consequences of IL-21 production in HIV-infected individuals: a longitudinal and cross-sectional study. J Immunol. 2010;184:114-26 pubmed publisher
Kuttruff S, Koch S, Kelp A, Pawelec G, Rammensee H, Steinle A. NKp80 defines and stimulates a reactive subset of CD8 T cells. Blood. 2009;113:358-69 pubmed publisher
Palendira U, Chinn R, Raza W, Piper K, Pratt G, Machado L, et al. Selective accumulation of virus-specific CD8+ T cells with unique homing phenotype within the human bone marrow. Blood. 2008;112:3293-302 pubmed publisher
Thakral D, Dobbins J, Devine L, Kavathas P. Differential expression of the human CD8beta splice variants and regulation of the M-2 isoform by ubiquitination. J Immunol. 2008;180:7431-42 pubmed
Roque S, Nobrega C, Appelberg R, Correia Neves M. IL-10 underlies distinct susceptibility of BALB/c and C57BL/6 mice to Mycobacterium avium infection and influences efficacy of antibiotic therapy. J Immunol. 2007;178:8028-35 pubmed
Smeltz R. Profound enhancement of the IL-12/IL-18 pathway of IFN-gamma secretion in human CD8+ memory T cell subsets via IL-15. J Immunol. 2007;178:4786-92 pubmed
product information
Antigen :
CD45RA
Apps. Abbrev. :
Flow Cytometry
Cat # :
304121
Clone :
HI100
Item :
PerCP/Cyanine5.5 anti-human CD45RA
Isotype :
Mouse IgG2b, κ
Other Names :
GP180, L-CA, LCA, LY5, T200, PTPRC
Size :
25 tests
Price (USD) :
132 USD
Reactivity :
Human, Cross-Reactivity: Chimpanzee
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PERCP_CYANINE5.5
Application Notes :
Additional reported applications (for relevant formats of this clone) include: inhibition of CD45 functions 2 , immunohistochemical staining of frozen tissue sections 3 and formalin-fixed paraffin-embedded tissue sections 4 , and immunocytochemistry 15,16 .
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA