product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Pacific Blue™ anti-human CD45RA
catalog :
304117
quantity :
25 μg
price :
105 USD
clonality :
monoclonal
host :
mouse
conjugate :
Pacific Blue
clone name :
HI100
reactivity :
human
application :
flow cytometry
more info or order :
citations: 21
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human
Bendall S, Simonds E, Qiu P, Amir E, Krutzik P, Finck R, et al. Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. Science. 2011;332:687-96 pubmed publisher
Rajamanickam A, Munisankar S, Bhootra Y, Dolla C, Thiruvengadam K, Nutman T, et al. Altered levels of memory T cell subsets and common γc cytokines in Strongyloides stercoralis infection and partial reversal following anthelmintic treatment. PLoS Negl Trop Dis. 2018;12:e0006481 pubmed publisher
Santoni de Sio F, Passerini L, Restelli S, Valente M, Pramov A, Maccari M, et al. Role of human forkhead box P3 in early thymic maturation and peripheral T-cell homeostasis. J Allergy Clin Immunol. 2018;142:1909-1921.e9 pubmed publisher
Kubo M, Satoh T, Ishiyama H, Tabata K, Tsumura H, Komori S, et al. Enhanced activated T cell subsets in prostate cancer patients receiving iodine-125 low-dose-rate prostate brachytherapy. Oncol Rep. 2018;39:417-424 pubmed publisher
He X, Smeets R, van Rijssen E, Boots A, Joosten I, Koenen H. Single CD28 stimulation induces stable and polyclonal expansion of human regulatory T cells. Sci Rep. 2017;7:43003 pubmed publisher
Wang R, Wang Y, Zhang Y, Gabrelow C, Zhang Y, Chi V, et al. Rational design of a Kv1.3 channel-blocking antibody as a selective immunosuppressant. Proc Natl Acad Sci U S A. 2016;113:11501-11506 pubmed
Rundberg Nilsson A, Soneji S, Adolfsson S, Bryder D, Pronk C. Human and Murine Hematopoietic Stem Cell Aging Is Associated with Functional Impairments and Intrinsic Megakaryocytic/Erythroid Bias. PLoS ONE. 2016;11:e0158369 pubmed publisher
Trinité B, Chan C, Lee C, Mahajan S, Luo Y, Muesing M, et al. Suppression of Foxo1 activity and down-modulation of CD62L (L-selectin) in HIV-1 infected resting CD4 T cells. PLoS ONE. 2014;9:e110719 pubmed publisher
Kurktschiev P, Raziorrouh B, Schraut W, Backmund M, Wächtler M, Wendtner C, et al. Dysfunctional CD8+ T cells in hepatitis B and C are characterized by a lack of antigen-specific T-bet induction. J Exp Med. 2014;211:2047-59 pubmed publisher
Blatt K, Herrmann H, Hoermann G, Willmann M, Cerny Reiterer S, Sadovnik I, et al. Identification of campath-1 (CD52) as novel drug target in neoplastic stem cells in 5q-patients with MDS and AML. Clin Cancer Res. 2014;20:3589-602 pubmed publisher
Pellicano M, Buffa S, Goldeck D, Bulati M, Martorana A, Caruso C, et al. Evidence for less marked potential signs of T-cell immunosenescence in centenarian offspring than in the general age-matched population. J Gerontol A Biol Sci Med Sci. 2014;69:495-504 pubmed publisher
Guerau de Arellano M, Smith K, Godlewski J, Liu Y, Winger R, Lawler S, et al. Micro-RNA dysregulation in multiple sclerosis favours pro-inflammatory T-cell-mediated autoimmunity. Brain. 2011;134:3578-89 pubmed publisher
Derhovanessian E, Maier A, Beck R, Jahn G, Hähnel K, Slagboom P, et al. Hallmark features of immunosenescence are absent in familial longevity. J Immunol. 2010;185:4618-24 pubmed publisher
Alanio C, Lemaitre F, Law H, Hasan M, Albert M. Enumeration of human antigen-specific naive CD8+ T cells reveals conserved precursor frequencies. Blood. 2010;115:3718-25 pubmed publisher
Han L, Wierenga A, Rozenveld Geugien M, van de Lande K, Vellenga E, Schuringa J. Single-cell STAT5 signal transduction profiling in normal and leukemic stem and progenitor cell populations reveals highly distinct cytokine responses. PLoS ONE. 2009;4:e7989 pubmed publisher
Iannello A, Boulassel M, Samarani S, Debbeche O, Tremblay C, Toma E, et al. Dynamics and consequences of IL-21 production in HIV-infected individuals: a longitudinal and cross-sectional study. J Immunol. 2010;184:114-26 pubmed publisher
Kuttruff S, Koch S, Kelp A, Pawelec G, Rammensee H, Steinle A. NKp80 defines and stimulates a reactive subset of CD8 T cells. Blood. 2009;113:358-69 pubmed publisher
Palendira U, Chinn R, Raza W, Piper K, Pratt G, Machado L, et al. Selective accumulation of virus-specific CD8+ T cells with unique homing phenotype within the human bone marrow. Blood. 2008;112:3293-302 pubmed publisher
Thakral D, Dobbins J, Devine L, Kavathas P. Differential expression of the human CD8beta splice variants and regulation of the M-2 isoform by ubiquitination. J Immunol. 2008;180:7431-42 pubmed
Roque S, Nobrega C, Appelberg R, Correia Neves M. IL-10 underlies distinct susceptibility of BALB/c and C57BL/6 mice to Mycobacterium avium infection and influences efficacy of antibiotic therapy. J Immunol. 2007;178:8028-35 pubmed
Smeltz R. Profound enhancement of the IL-12/IL-18 pathway of IFN-gamma secretion in human CD8+ memory T cell subsets via IL-15. J Immunol. 2007;178:4786-92 pubmed
product information
Antigen :
CD45RA
Apps. Abbrev. :
Flow Cytometry
Cat # :
304117
Clone :
HI100
Item :
Pacific Blue™ anti-human CD45RA
Isotype :
Mouse IgG2b, κ
Other Names :
GP180, L-CA, LCA, LY5, T200, PTPRC
Size :
25 μg
Price (USD) :
105 USD
Reactivity :
Human, Cross-Reactivity: Chimpanzee
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PB
Application Notes :
Additional reported applications (for relevant formats of this clone) include: inhibition of CD45 functions 2 , immunohistochemical staining of frozen tissue sections 3 and formalin-fixed paraffin-embedded tissue sections 4 , and immunocytochemistry 15,16 .
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA