product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PE/Cyanine7 anti-human CD45
catalog :
304016
quantity :
100 tests
price :
283 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE/Cy7
clone name :
HI30
reactivity :
human, mouse
application :
immunohistochemistry, flow cytometry
more info or order :
citations: 44
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig s1c
Wang Y, Mohseni M, Grauel A, Diez J, Guan W, Liang S, et al. SHP2 blockade enhances anti-tumor immunity via tumor cell intrinsic and extrinsic mechanisms. Sci Rep. 2021;11:1399 pubmed publisher
  • flow cytometry; human; loading ...; fig 4b
Suzuki D, Flahou C, Yoshikawa N, Stirblyte I, Hayashi Y, Sawaguchi A, et al. iPSC-Derived Platelets Depleted of HLA Class I Are Inert to Anti-HLA Class I and Natural Killer Cell Immunity. Stem Cell Reports. 2020;14:49-59 pubmed publisher
  • flow cytometry; human; loading ...; fig 3b
Xiao X, Lai W, Xie H, Liu Y, Guo W, Liu Y, et al. Targeting JNK pathway promotes human hematopoietic stem cell expansion. Cell Discov. 2019;5:2 pubmed publisher
  • immunohistochemistry; mouse; 1:200; fig 2f
Zhang H, Song Y, Yang H, Liu Z, Gao L, Liang X, et al. Tumor cell-intrinsic Tim-3 promotes liver cancer via NF-κB/IL-6/STAT3 axis. Oncogene. 2018;37:2456-2468 pubmed publisher
  • flow cytometry; human; loading ...; fig 1
Lima P, Chen Z, Tayab A, Murphy M, Pudwell J, Smith G, et al. Circulating progenitor and angiogenic cell frequencies are abnormally static over pregnancy in women with preconception diabetes: A pilot study. PLoS ONE. 2017;12:e0172988 pubmed publisher
  • flow cytometry; human
Cordeiro O, Chypre M, Brouard N, Rauber S, Alloush F, Romera Hernandez M, et al. Integrin-Alpha IIb Identifies Murine Lymph Node Lymphatic Endothelial Cells Responsive to RANKL. PLoS ONE. 2016;11:e0151848 pubmed publisher
  • flow cytometry; human; tbl 1
Magri G, Miyajima M, Bascones S, Mortha A, Puga I, Cassis L, et al. Innate lymphoid cells integrate stromal and immunological signals to enhance antibody production by splenic marginal zone B cells. Nat Immunol. 2014;15:354-364 pubmed publisher
  • flow cytometry; human
Bendall S, Simonds E, Qiu P, Amir E, Krutzik P, Finck R, et al. Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. Science. 2011;332:687-96 pubmed publisher
Woodcock V, Chen J, Purshouse K, Butcher C, Collins L, Haddon C, et al. PemBla: A Phase 1 study of intravesical pembrolizumab in recurrent non-muscle-invasive bladder cancer. BJUI Compass. 2023;4:322-330 pubmed publisher
Wong H, Sheng Q, Hesterberg A, Croessmann S, Rios B, Giri K, et al. Single cell analysis of cribriform prostate cancer reveals cell intrinsic and tumor microenvironmental pathways of aggressive disease. Nat Commun. 2022;13:6036 pubmed publisher
Omer Javed A, Pedrazzani G, Albano L, Ghaus S, Latroche C, Manzi M, et al. Mobilization-based chemotherapy-free engraftment of gene-edited human hematopoietic stem cells. Cell. 2022;185:2248-2264.e21 pubmed publisher
Moquin Beaudry G, Benabdallah B, Maggiorani D, Le O, Li Y, Colas C, et al. Autologous humanized mouse models of iPSC-derived tumors enable characterization and modulation of cancer-immune cell interactions. Cell Rep Methods. 2022;2:100153 pubmed publisher
Liang J, Huang G, Liu X, Taghavifar F, Liu N, Wang Y, et al. The ZIP8/SIRT1 axis regulates alveolar progenitor cell renewal in aging and idiopathic pulmonary fibrosis. J Clin Invest. 2022;132: pubmed publisher
Gur C, Wang S, Sheban F, Zada M, Li B, Kharouf F, et al. LGR5 expressing skin fibroblasts define a major cellular hub perturbed in scleroderma. Cell. 2022;185:1373-1388.e20 pubmed publisher
Shiraki N, Maruyama K, Hayashi R, Oguchi A, Murakawa Y, Katayama T, et al. PAX6-positive microglia evolve locally in hiPSC-derived ocular organoids. Stem Cell Reports. 2022;17:221-230 pubmed publisher
Higham A, Baker J, Jackson N, Shah R, Lea S, Singh D. Dysregulation of the CD163-Haptoglobin Axis in the Airways of COPD Patients. Cells. 2021;11: pubmed publisher
Otano I, Azpilikueta A, Glez Vaz J, Alvarez M, Medina Echeverz J, Cortés Domínguez I, et al. CD137 (4-1BB) costimulation of CD8+ T cells is more potent when provided in cis than in trans with respect to CD3-TCR stimulation. Nat Commun. 2021;12:7296 pubmed publisher
Bhargavan B, Woollard S, McMillan J, Kanmogne G. CCR5 antagonist reduces HIV-induced amyloidogenesis, tau pathology, neurodegeneration, and blood-brain barrier alterations in HIV-infected hu-PBL-NSG mice. Mol Neurodegener. 2021;16:78 pubmed publisher
Che L, Liu J, Huo J, Luo R, Xu R, He C, et al. A single-cell atlas of liver metastases of colorectal cancer reveals reprogramming of the tumor microenvironment in response to preoperative chemotherapy. Cell Discov. 2021;7:80 pubmed publisher
Brito Pérez Y, Camacho Pacheco R, Plazola Camacho N, Soriano Becerril D, Coronado Zarco I, Arreola Ramírez G, et al. Impaired T helper cell responses in human immunodeficiency virus-exposed uninfected newborns. Immun Inflamm Dis. 2021;9:1541-1553 pubmed publisher
Liu X, Rowan S, Liang J, Yao C, Huang G, Deng N, et al. Categorization of lung mesenchymal cells in development and fibrosis. iScience. 2021;24:102551 pubmed publisher
Hohmann M, Habiel D, Espíndola M, Huang G, Jones I, Narayanan R, et al. Antibody-mediated depletion of CCR10+EphA3+ cells ameliorates fibrosis in IPF. JCI Insight. 2021;6: pubmed publisher
Kenswil K, Pisterzi P, Sanchez Duffhues G, van Dijk C, Lolli A, Knuth C, et al. Endothelium-derived stromal cells contribute to hematopoietic bone marrow niche formation. Cell Stem Cell. 2021;28:653-670.e11 pubmed publisher
Pierini S, Tanyi J, Simpkins F, George E, Uribe Herranz M, Drapkin R, et al. Ovarian granulosa cell tumor characterization identifies FOXL2 as an immunotherapeutic target. JCI Insight. 2020;5: pubmed publisher
Aung A, Kumar V, Theprungsirikul J, Davey S, Varghese S. An Engineered Tumor-on-a-Chip Device with Breast Cancer-Immune Cell Interactions for Assessing T-cell Recruitment. Cancer Res. 2020;80:263-275 pubmed publisher
Brown C, Gudjonson H, Pritykin Y, Deep D, Lavallée V, Mendoza A, et al. Transcriptional Basis of Mouse and Human Dendritic Cell Heterogeneity. Cell. 2019;179:846-863.e24 pubmed publisher
Bravo Flores E, Mancilla Herrera I, Espino y Sosa S, Ortiz Ramirez M, Flores Rueda V, Ibargüengoitia Ochoa F, et al. Macrophage Populations in Visceral Adipose Tissue from Pregnant Women: Potential Role of Obesity in Maternal Inflammation. Int J Mol Sci. 2018;19: pubmed publisher
Linedale R, Schmidt C, King B, Ganko A, Simpson F, Panizza B, et al. Elevated frequencies of CD8 T cells expressing PD-1, CTLA-4 and Tim-3 within tumour from perineural squamous cell carcinoma patients. PLoS ONE. 2017;12:e0175755 pubmed publisher
Sugden S, Pham T, Cohen E. HIV-1 Vpu Downmodulates ICAM-1 Expression, Resulting in Decreased Killing of Infected CD4+ T Cells by NK Cells. J Virol. 2017;91: pubmed publisher
Li J, Phadnis Moghe A, Crawford R, Kaminski N. Aryl hydrocarbon receptor activation by 2,3,7,8-tetrachlorodibenzo-p-dioxin impairs human B lymphopoiesis. Toxicology. 2017;378:17-24 pubmed publisher
Charmsaz S, Al Ejeh F, Yeadon T, Miller K, Smith F, Stringer B, et al. EphA3 as a target for antibody immunotherapy in acute lymphoblastic leukemia. Leukemia. 2017;31:1779-1787 pubmed publisher
Pecht T, Haim Y, Bashan N, Shapiro H, Harman Boehm I, Kirshtein B, et al. Circulating Blood Monocyte Subclasses and Lipid-Laden Adipose Tissue Macrophages in Human Obesity. PLoS ONE. 2016;11:e0159350 pubmed publisher
Panjwani M, Smith J, Schutsky K, Gnanandarajah J, O Connor C, Powell D, et al. Feasibility and Safety of RNA-transfected CD20-specific Chimeric Antigen Receptor T Cells in Dogs with Spontaneous B Cell Lymphoma. Mol Ther. 2016;24:1602-14 pubmed publisher
Vishnoi M, Peddibhotla S, Yin W, T Scamardo A, George G, Hong D, et al. The isolation and characterization of CTC subsets related to breast cancer dormancy. Sci Rep. 2015;5:17533 pubmed publisher
Bhatwadekar A, Yan Y, Stepps V, Hazra S, Korah M, BARTELMEZ S, et al. miR-92a Corrects CD34+ Cell Dysfunction in Diabetes by Modulating Core Circadian Genes Involved in Progenitor Differentiation. Diabetes. 2015;64:4226-37 pubmed publisher
Lee J, Breton G, Oliveira T, Zhou Y, Aljoufi A, PUHR S, et al. Restricted dendritic cell and monocyte progenitors in human cord blood and bone marrow. J Exp Med. 2015;212:385-99 pubmed publisher
Breton G, Lee J, Zhou Y, Schreiber J, Keler T, PUHR S, et al. Circulating precursors of human CD1c+ and CD141+ dendritic cells. J Exp Med. 2015;212:401-13 pubmed publisher
Marquardt N, Béziat V, Nyström S, Hengst J, Ivarsson M, Kekäläinen E, et al. Cutting edge: identification and characterization of human intrahepatic CD49a+ NK cells. J Immunol. 2015;194:2467-71 pubmed publisher
Li L, Torres Coronado M, Gu A, Rao A, Gardner A, Epps E, et al. Enhanced genetic modification of adult growth factor mobilized peripheral blood hematopoietic stem and progenitor cells with rapamycin. Stem Cells Transl Med. 2014;3:1199-208 pubmed publisher
Bushway M, Gerber S, Fenton B, Miller R, Lord E, Murphy S. Morphological and phenotypic analyses of the human placenta using whole mount immunofluorescence. Biol Reprod. 2014;90:110 pubmed publisher
Palpant N, Pabon L, Rabinowitz J, Hadland B, Stoick Cooper C, Paige S, et al. Transmembrane protein 88: a Wnt regulatory protein that specifies cardiomyocyte development. Development. 2013;140:3799-808 pubmed publisher
Oeztuerk Winder F, Guinot A, Ochalek A, Ventura J. Regulation of human lung alveolar multipotent cells by a novel p38α MAPK/miR-17-92 axis. EMBO J. 2012;31:3431-41 pubmed publisher
Morozov A, Downey R, Healey J, Moreira A, Lou E, Franceschino A, et al. Benign mesenchymal stromal cells in human sarcomas. Clin Cancer Res. 2010;16:5630-40 pubmed publisher
Jiang Q, Zhang L, Wang R, Jeffrey J, Washburn M, Brouwer D, et al. FoxP3+CD4+ regulatory T cells play an important role in acute HIV-1 infection in humanized Rag2-/-gammaC-/- mice in vivo. Blood. 2008;112:2858-68 pubmed publisher
product information
Antigen :
CD45
Apps. Abbrev. :
FC
Cat # :
304016
Clone :
HI30
Item :
PE/Cyanine7 anti-human CD45
Isotype :
Mouse IgG1, κ
Other Names :
LCA, T200
Size :
100 tests
Price (USD) :
283 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PE_CYANINE7
Application Notes :
Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections and formalin-fixed paraffin-embedded tissue sections^9, inhibition of CD45 functions^4, immunofluorescence^11, Western blotting^3, and spatial biology (IBEX)^16,17.It was found that the HI30 clone and the 2D1 clone can cross block each other's binding.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA