product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
APC anti-human CD41
catalog :
303709
quantity :
25 tests
price :
139 USD
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
HIP8
reactivity :
human
application :
flow cytometry
more info or order :
citations: 23
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human
Bendall S, Simonds E, Qiu P, Amir E, Krutzik P, Finck R, et al. Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. Science. 2011;332:687-96 pubmed publisher
Shen W, Li H, Zha A, Luo R, Zhang Y, Luo C, et al. Platelets reprogram monocyte functions by secreting MMP-9 to benefit postoperative outcomes following acute aortic dissection. iScience. 2023;26:106805 pubmed publisher
Liu Y, Zuo X, Chen P, Hu X, Sheng Z, Liu A, et al. Deciphering transcriptome alterations in bone marrow hematopoiesis at single-cell resolution in immune thrombocytopenia. Signal Transduct Target Ther. 2022;7:347 pubmed publisher
Wang B, Wang C, Wan Y, Gao J, Ma Y, Zhang Y, et al. Decoding the pathogenesis of Diamond-Blackfan anemia using single-cell RNA-seq. Cell Discov. 2022;8:41 pubmed publisher
Guo Q, Malloy M, Roweth H, McAllister S, Italiano J, Battinelli E. Platelets upregulate tumor cell programmed death ligand 1 in an epidermal growth factor receptor-dependent manner in vitro. Blood Adv. 2022;6:5668-5675 pubmed publisher
Dickerson K, Qu C, Gao Q, Iacobucci I, Gu Z, Yoshihara H, et al. ZNF384 Fusion Oncoproteins Drive Lineage Aberrancy in Acute Leukemia. Blood Cancer Discov. 2022;3:240-263 pubmed publisher
Palacios Acedo A, Mezouar S, M xe8 ge D, Crescence L, Dubois C, Panicot Dubois L. P2RY12-Inhibitors Reduce Cancer-Associated Thrombosis and Tumor Growth in Pancreatic Cancers. Front Oncol. 2021;11:704945 pubmed publisher
Zhang G, Chen H, Guo Y, Zhang W, Jiang Q, Zhang S, et al. Activation of Platelet NLRP3 Inflammasome in Crohn's Disease. Front Pharmacol. 2021;12:705325 pubmed publisher
Sato M, Shiga Y, Takayama N, Sone M, Kosaka K, Motegi I, et al. The Effect of Megakaryocytes and Platelets Derived from Human-Induced Pluripotent Stem Cells on Bone Formation. Spine Surg Relat Res. 2021;5:196-204 pubmed publisher
Hug S, Bernhard S, Stratmann A, Erber M, Wohlgemuth L, Knapp C, et al. Activation of Neutrophil Granulocytes by Platelet-Activating Factor Is Impaired During Experimental Sepsis. Front Immunol. 2021;12:642867 pubmed publisher
Machata S, Sreekantapuram S, Hünniger K, Kurzai O, Dunker C, Schubert K, et al. Significant Differences in Host-Pathogen Interactions Between Murine and Human Whole Blood. Front Immunol. 2020;11:565869 pubmed publisher
Botha J, Pugsley H, Handberg A. Conventional, High-Resolution and Imaging Flow Cytometry: Benchmarking Performance in Characterisation of Extracellular Vesicles. Biomedicines. 2021;9: pubmed publisher
Rodda L, Netland J, Shehata L, Pruner K, Morawski P, Thouvenel C, et al. Functional SARS-CoV-2-Specific Immune Memory Persists after Mild COVID-19. Cell. 2021;184:169-183.e17 pubmed publisher
Rolfes V, Ribeiro L, Hawwari I, Böttcher L, Rosero N, Maasewerd S, et al. Platelets Fuel the Inflammasome Activation of Innate Immune Cells. Cell Rep. 2020;31:107615 pubmed publisher
Suzuki D, Flahou C, Yoshikawa N, Stirblyte I, Hayashi Y, Sawaguchi A, et al. iPSC-Derived Platelets Depleted of HLA Class I Are Inert to Anti-HLA Class I and Natural Killer Cell Immunity. Stem Cell Reports. 2020;14:49-59 pubmed publisher
Sung P, Huang T, Hsieh S. Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2. Nat Commun. 2019;10:2402 pubmed publisher
Pellin D, Loperfido M, Baricordi C, Wolock S, Montepeloso A, Weinberg O, et al. A comprehensive single cell transcriptional landscape of human hematopoietic progenitors. Nat Commun. 2019;10:2395 pubmed publisher
Costa B, Eisemann T, Strelau J, Spaan I, Korshunov A, Liu H, et al. Intratumoral platelet aggregate formation in a murine preclinical glioma model depends on podoplanin expression on tumor cells. Blood Adv. 2019;3:1092-1102 pubmed publisher
Shlamkovich T, Aharon L, Koslawsky D, Einav Y, Papo N. Targeting the Tie2-αvβ3 integrin axis with bi-specific reagents for the inhibition of angiogenesis. BMC Biol. 2018;16:92 pubmed publisher
Ito Y, Nakamura S, Sugimoto N, Shigemori T, Kato Y, Ohno M, et al. Turbulence Activates Platelet Biogenesis to Enable Clinical Scale Ex Vivo Production. Cell. 2018;174:636-648.e18 pubmed publisher
Pircher J, Czermak T, Ehrlich A, Eberle C, Gaitzsch E, Margraf A, et al. Cathelicidins prime platelets to mediate arterial thrombosis and tissue inflammation. Nat Commun. 2018;9:1523 pubmed publisher
Best M, Sol N, In t Veld S, Vancura A, Muller M, Niemeijer A, et al. Swarm Intelligence-Enhanced Detection of Non-Small-Cell Lung Cancer Using Tumor-Educated Platelets. Cancer Cell. 2017;32:238-252.e9 pubmed publisher
Moussa M, Fontana P, Hamdan F, Cattani Lorente M, Scherrer S, Banakh O, et al. Modulation of osteoblast behavior on TiNxOy coatings by altering the N/O stoichiometry while maintaining a high thrombogenic potential. J Biomater Appl. 2016;30:1219-29 pubmed publisher
product information
Antigen :
CD41
Apps. Abbrev. :
FC
Cat # :
303709
Clone :
HIP8
Item :
APC anti-human CD41
Isotype :
Mouse IgG1, κ
Other Names :
gpIIb, CD41a
Size :
25 tests
Price (USD) :
139 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
APC
Application Notes :
Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections and blocking of platelet aggregation^2. The HIP8 antibody has been reported to block the activation of platelets by various stimuli, including collagen, and ADP.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA