product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PerCP/Cyanine5.5 anti-human CD33
catalog :
303414
quantity :
100 tests
price :
382 USD
clonality :
monoclonal
host :
mouse
conjugate :
PerCP/Cy5.5
clone name :
WM53
reactivity :
human
application :
immunohistochemistry, flow cytometry
more info or order :
citations: 19
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; human; 1:300; loading ...; fig 7b
Ding L, Hayes M, Photenhauer A, Eaton K, Li Q, Ocadiz Ruiz R, et al. Schlafen 4-expressing myeloid-derived suppressor cells are induced during murine gastric metaplasia. J Clin Invest. 2016;126:2867-80 pubmed publisher
  • flow cytometry; human; loading ...; fig 1a
Younis R, Han K, Webb T. Human Head and Neck Squamous Cell Carcinoma-Associated Semaphorin 4D Induces Expansion of Myeloid-Derived Suppressor Cells. J Immunol. 2016;196:1419-29 pubmed publisher
  • flow cytometry; human
Bendall S, Simonds E, Qiu P, Amir E, Krutzik P, Finck R, et al. Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. Science. 2011;332:687-96 pubmed publisher
Blomberg O, Spagnuolo L, Garner H, Voorwerk L, Isaeva O, van Dyk E, et al. IL-5-producing CD4+ T cells and eosinophils cooperate to enhance response to immune checkpoint blockade in breast cancer. Cancer Cell. 2023;41:106-123.e10 pubmed publisher
Wu L, Xu Y, Zhao H, Zhou Y, Chen Y, Yang S, et al. FcγRIIB potentiates differentiation of myeloid-derived suppressor cells to mediate tumor immunoescape. Theranostics. 2022;12:842-858 pubmed publisher
Le Q, Castro S, Tang T, Loeb A, Hylkema T, McKay C, et al. Therapeutic Targeting of Mesothelin with Chimeric Antigen Receptor T Cells in Acute Myeloid Leukemia. Clin Cancer Res. 2021;27:5718-5730 pubmed publisher
Yankova E, Blackaby W, Albertella M, Rak J, De Braekeleer E, Tsagkogeorga G, et al. Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia. Nature. 2021;593:597-601 pubmed publisher
Zavidij O, Haradhvala N, Mouhieddine T, Sklavenitis Pistofidis R, Cai S, Reidy M, et al. Single-cell RNA sequencing reveals compromised immune microenvironment in precursor stages of multiple myeloma. Nat Cancer. 2020;1:493-506 pubmed publisher
Kim S, Saeidi S, Zhong X, Gwak S, Muna I, Park S, et al. Breast cancer cell debris diminishes therapeutic efficacy through heme oxygenase-1-mediated inactivation of M1-like tumor-associated macrophages. Neoplasia. 2020;22:606-616 pubmed publisher
Sztwiertnia I, Schenz J, Bomans K, Schaack D, Ohnesorge J, Tamulyte S, et al. Sevoflurane depletes macrophages from the melanoma microenvironment. PLoS ONE. 2020;15:e0233789 pubmed publisher
Brykczynska U, Geigges M, Wiedemann S, Dror E, Böni Schnetzler M, Hess C, et al. Distinct Transcriptional Responses across Tissue-Resident Macrophages to Short-Term and Long-Term Metabolic Challenge. Cell Rep. 2020;30:1627-1643.e7 pubmed publisher
Jaitin D, Adlung L, Thaiss C, Weiner A, Li B, Descamps H, et al. Lipid-Associated Macrophages Control Metabolic Homeostasis in a Trem2-Dependent Manner. Cell. 2019;178:686-698.e14 pubmed publisher
Zhong J, Scholz T, Yau A, Guérard S, Huffmeier U, Burkhardt H, et al. Mannan-induced Nos2 in macrophages enhances IL-17-driven psoriatic arthritis by innate lymphocytes. Sci Adv. 2018;4:eaas9864 pubmed publisher
Si Y, Wen Y, Kelly S, Chong A, Collier J. Intranasal delivery of adjuvant-free peptide nanofibers elicits resident CD8+ T cell responses. J Control Release. 2018;282:120-130 pubmed publisher
Kuen J, Darowski D, Kluge T, Majety M. Pancreatic cancer cell/fibroblast co-culture induces M2 like macrophages that influence therapeutic response in a 3D model. PLoS ONE. 2017;12:e0182039 pubmed publisher
Norton S, Dunn E, McCall J, Munro F, Kemp R. Gut macrophage phenotype is dependent on the tumor microenvironment in colorectal cancer. Clin Transl Immunology. 2016;5:e76 pubmed publisher
Kraus H, Kaiser S, Aumann K, Bönelt P, Salzer U, Vestweber D, et al. A feeder-free differentiation system identifies autonomously proliferating B cell precursors in human bone marrow. J Immunol. 2014;192:1044-54 pubmed publisher
Capietto A, Kim S, Sanford D, Linehan D, Hikida M, Kumosaki T, et al. Down-regulation of PLCγ2-β-catenin pathway promotes activation and expansion of myeloid-derived suppressor cells in cancer. J Exp Med. 2013;210:2257-71 pubmed publisher
Garg A, Spector S. HIV type 1 gp120-induced expansion of myeloid derived suppressor cells is dependent on interleukin 6 and suppresses immunity. J Infect Dis. 2014;209:441-51 pubmed publisher
product information
Antigen :
CD33
Apps. Abbrev. :
FC
Cat # :
303414
Clone :
WM53
Item :
PerCP/Cyanine5.5 anti-human CD33
Isotype :
Mouse IgG1, κ
Other Names :
Siglec-3, gp67, p67
Size :
100 tests
Price (USD) :
382 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PERCP_CYANINE5.5
Immunogen :
Human myeloid leukaemia cells.
Application Notes :
Additional reported applications (for the relevant formats) include: immunoprecipitation, Western blotting^3, induction of cytokine production^3, and immunofluorescence^4. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. Nos. 303437 & 303438).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA