product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PE/Cyanine7 anti-human CD31
catalog :
303117
quantity :
25 tests
price :
141 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE/Cy7
clone name :
WM59
reactivity :
human, rhesus macaque
application :
flow cytometry
more info or order :
citations: 23
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; fig s4a
Iwahashi N, Umakoshi H, Seki T, Gomez Sanchez C, Mukai K, Suematsu M, et al. Characterization of Aldosterone-producing Cell Cluster (APCC) at Single-cell Resolution. J Clin Endocrinol Metab. 2022;107:2439-2448 pubmed publisher
  • flow cytometry; human; loading ...
Krogh Nielsen M, Hector S, Allen K, Subhi Y, Sørensen T. Altered activation state of circulating neutrophils in patients with neovascular age-related macular degeneration. Immun Ageing. 2017;14:18 pubmed publisher
Meng Y, Jiang X, Zhao X, Meng Q, Wu S, Chen Y, et al. Hexokinase 2-driven glycolysis in pericytes activates their contractility leading to tumor blood vessel abnormalities. Nat Commun. 2021;12:6011 pubmed publisher
Liu X, Rowan S, Liang J, Yao C, Huang G, Deng N, et al. Categorization of lung mesenchymal cells in development and fibrosis. iScience. 2021;24:102551 pubmed publisher
Chioh F, Fong S, Young B, Wu K, Siau A, Krishnan S, et al. Convalescent COVID-19 patients are susceptible to endothelial dysfunction due to persistent immune activation. elife. 2021;10: pubmed publisher
Takeda A, Jalkanen S. Single-Cell Transcriptomics of Human Lymph Node Stroma. STAR Protoc. 2020;1:100021 pubmed publisher
Penkava F, Velasco Herrera M, Young M, Yager N, Nwosu L, Pratt A, et al. Single-cell sequencing reveals clonal expansions of pro-inflammatory synovial CD8 T cells expressing tissue-homing receptors in psoriatic arthritis. Nat Commun. 2020;11:4767 pubmed publisher
Kieffer Y, Hocine H, Gentric G, Pelon F, Bernard C, Bourachot B, et al. Single-Cell Analysis Reveals Fibroblast Clusters Linked to Immunotherapy Resistance in Cancer. Cancer Discov. 2020;10:1330-1351 pubmed publisher
Pelon F, Bourachot B, Kieffer Y, Magagna I, Mermet Meillon F, Bonnet I, et al. Cancer-associated fibroblast heterogeneity in axillary lymph nodes drives metastases in breast cancer through complementary mechanisms. Nat Commun. 2020;11:404 pubmed publisher
Takeda A, Hollmen M, Dermadi D, Pan J, Brulois K, Kaukonen R, et al. Single-Cell Survey of Human Lymphatics Unveils Marked Endothelial Cell Heterogeneity and Mechanisms of Homing for Neutrophils. Immunity. 2019;51:561-572.e5 pubmed publisher
Nguyen M, De Ninno A, Mencattini A, Mermet Meillon F, Fornabaio G, Evans S, et al. Dissecting Effects of Anti-cancer Drugs and Cancer-Associated Fibroblasts by On-Chip Reconstitution of Immunocompetent Tumor Microenvironments. Cell Rep. 2018;25:3884-3893.e3 pubmed publisher
Costa A, Kieffer Y, Scholer Dahirel A, Pelon F, Bourachot B, Cardon M, et al. Fibroblast Heterogeneity and Immunosuppressive Environment in Human Breast Cancer. Cancer Cell. 2018;33:463-479.e10 pubmed publisher
Irizarry D, Longaker M, Wan D. Commentary on: Adipose Stem Cell Function Maintained with Age: An Intra-Subject Study of Long-Term Cryopreserved Cells. Aesthet Surg J. 2017;37:464-465 pubmed publisher
Donnenberg V, Donnenberg A. Coping with artifact in the analysis of flow cytometric data. Methods. 2015;82:3-11 pubmed publisher
Hebel K, Weinert S, Kuropka B, Knolle J, Kosak B, Jorch G, et al. CD4+ T cells from human neonates and infants are poised spontaneously to run a nonclassical IL-4 program. J Immunol. 2014;192:5160-70 pubmed publisher
Bushway M, Gerber S, Fenton B, Miller R, Lord E, Murphy S. Morphological and phenotypic analyses of the human placenta using whole mount immunofluorescence. Biol Reprod. 2014;90:110 pubmed publisher
Holdsworth Carson S, Zaitseva M, Vollenhoven B, Rogers P. Clonality of smooth muscle and fibroblast cell populations isolated from human fibroid and myometrial tissues. Mol Hum Reprod. 2014;20:250-9 pubmed publisher
Ardehali R, Ali S, Inlay M, Abilez O, Chen M, Blauwkamp T, et al. Prospective isolation of human embryonic stem cell-derived cardiovascular progenitors that integrate into human fetal heart tissue. Proc Natl Acad Sci U S A. 2013;110:3405-10 pubmed publisher
Zhang W, Wang J, Shu Y, Tang T, Zhu Z, Xia N, et al. Impaired thymic export and increased apoptosis account for regulatory T cell defects in patients with non-ST segment elevation acute coronary syndrome. J Biol Chem. 2012;287:34157-66 pubmed publisher
Oeztuerk Winder F, Guinot A, Ochalek A, Ventura J. Regulation of human lung alveolar multipotent cells by a novel p38α MAPK/miR-17-92 axis. EMBO J. 2012;31:3431-41 pubmed publisher
Wicki A, Rochlitz C, Orleth A, Ritschard R, Albrecht I, Herrmann R, et al. Targeting tumor-associated endothelial cells: anti-VEGFR2 immunoliposomes mediate tumor vessel disruption and inhibit tumor growth. Clin Cancer Res. 2012;18:454-64 pubmed publisher
Nagano M, Yamashita T, Hamada H, Ohneda K, Kimura K, Nakagawa T, et al. Identification of functional endothelial progenitor cells suitable for the treatment of ischemic tissue using human umbilical cord blood. Blood. 2007;110:151-60 pubmed
MacFadyen J, Haworth O, Roberston D, Hardie D, Webster M, Morris H, et al. Endosialin (TEM1, CD248) is a marker of stromal fibroblasts and is not selectively expressed on tumour endothelium. FEBS Lett. 2005;579:2569-75 pubmed
product information
Antigen :
CD31
Apps. Abbrev. :
FC
Cat # :
303117
Clone :
WM59
Item :
PE/Cyanine7 anti-human CD31
Isotype :
Mouse IgG1, κ
Other Names :
PECAM-1, EndoCAM
Size :
25 tests
Price (USD) :
141 USD
Reactivity :
Human, Cynomolgus, Rhesus
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PE_CYANINE7
Application Notes :
Clone WM59 has been reported to recognize the D2 extracellular portion of CD31.Additional reported applications (for the relevant formats) include: immunofluorescence microscopy^2, immunohistochemical staining of acetone-fixed frozen tissue sections^8, blocking of platelet aggregation^3, and spatial biology (IBEX)^11,12. Clone WM59 is not recommended for immunohistochemical staining of formalin-fixed paraffin-embedded sections. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 303143 & 303144).The purified WM59 antibody is useful as a capture antibody for a sandwich ELISA assay, when used in conjunction with biotin anti-human CD31 antibody (Cat. No. 536604) antibody as the detection antibody.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA