product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PE anti-human CD25
catalog :
302605
quantity :
25 tests
price :
39 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
BC96
reactivity :
human
application :
flow cytometry
more info or order :
citations: 53
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig s6a
Kuhny M, Forbes L, Çakan E, Vega Loza A, Kostiuk V, Dinesh R, et al. Disease-associated CTNNBL1 mutation impairs somatic hypermutation by decreasing nuclear AID. J Clin Invest. 2020;: pubmed publisher
  • flow cytometry; human; loading ...; fig s1
Canete P, Sweet R, Gonzalez Figueroa P, Papa I, Ohkura N, Bolton H, et al. Regulatory roles of IL-10-producing human follicular T cells. J Exp Med. 2019;: pubmed publisher
  • flow cytometry; human; loading ...; fig 1
Ondigo B, Ndombi E, Nicholson S, Oguso J, Carter J, Kittur N, et al. Functional Studies of T Regulatory Lymphocytes in Human Schistosomiasis in Western Kenya. Am J Trop Med Hyg. 2018;98:1770-1781 pubmed publisher
  • flow cytometry; human; loading ...; fig 4a
Li M, Zhang W, Liu J, Li M, Zhang Y, Xiong Y, et al. Dynamic changes in the immunological characteristics of T lymphocytes in surviving patients with severe fever with thrombocytopenia syndrome (SFTS). Int J Infect Dis. 2018;70:72-80 pubmed publisher
  • flow cytometry; human; loading ...; fig 1b
Bal S, Bernink J, Nagasawa M, Groot J, Shikhagaie M, Golebski K, et al. IL-1?, IL-4 and IL-12 control the fate of group 2 innate lymphoid cells in human airway inflammation in the lungs. Nat Immunol. 2016;17:636-45 pubmed publisher
  • flow cytometry; human; loading ...; fig 8a
James E, Gates T, LaFond R, Yamamoto S, Ni C, Mai D, et al. Neuroinvasive West Nile Infection Elicits Elevated and Atypically Polarized T Cell Responses That Promote a Pathogenic Outcome. PLoS Pathog. 2016;12:e1005375 pubmed publisher
  • flow cytometry; human; fig s1
Rochman Y, Yukawa M, Kartashov A, Barski A. Functional characterization of human T cell hyporesponsiveness induced by CTLA4-Ig. PLoS ONE. 2015;10:e0122198 pubmed publisher
Erdem A, Marin S, Pereira Martins D, Cortés R, Cunningham A, Pruis M, et al. The Glycolytic Gatekeeper PDK1 defines different metabolic states between genetically distinct subtypes of human acute myeloid leukemia. Nat Commun. 2022;13:1105 pubmed publisher
Houtsma R, Hogeling S, Schuringa J. CombiFlow: Flow cytometry-based identification and characterization of genetically and functionally distinct AML subclones. STAR Protoc. 2021;2:100864 pubmed publisher
Chen Y, Yan B, Xu F, Hui Z, Zhao G, Liu J, et al. Neoadjuvant chemoimmunotherapy in resectable stage IIIA/IIIB non-small cell lung cancer. Transl Lung Cancer Res. 2021;10:2193-2204 pubmed publisher
Loo Yau H, De Carvalho D. Measuring the effect of drug treatments on primary human CD8+ T cell activation and cytolytic potential. STAR Protoc. 2021;2:100549 pubmed publisher
Delacher M, Simon M, Sanderink L, Hotz Wagenblatt A, Wuttke M, Schambeck K, et al. Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells. Immunity. 2021;54:702-720.e17 pubmed publisher
Mengrelis K, Kucera F, Shahid N, Watt E, Ross S, Lau C, et al. T cell phenotype in paediatric heart transplant recipients. Pediatr Transplant. 2021;25:e13930 pubmed publisher
Zhang B, Wang Y, Huang S, Sun J, Wang M, Ma W, et al. Photoswitchable CAR-T Cell Function In Vitro and In Vivo via a Cleavable Mediator. Cell Chem Biol. 2020;: pubmed publisher
Dyson M, Masters E, Pazeraitis D, Perera R, Syrjänen J, Surade S, et al. Beyond affinity: selection of antibody variants with optimal biophysical properties and reduced immunogenicity from mammalian display libraries. MAbs. 2020;12:1829335 pubmed publisher
Vinogradova E, Zhang X, Remillard D, Lazar D, Suciu R, Wang Y, et al. An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells. Cell. 2020;182:1009-1026.e29 pubmed publisher
Wang A, Chen L, Wu R, Hao Y, McSwiggen D, Heckert A, et al. The Histone Chaperone FACT Induces Cas9 Multi-turnover Behavior and Modifies Genome Manipulation in Human Cells. Mol Cell. 2020;79:221-233.e5 pubmed publisher
Klemm F, Maas R, Bowman R, Kornete M, Soukup K, Nassiri S, et al. Interrogation of the Microenvironmental Landscape in Brain Tumors Reveals Disease-Specific Alterations of Immune Cells. Cell. 2020;181:1643-1660.e17 pubmed publisher
Saadati S, Eskandari V, Rahmani F, Mahmoudi M, Rahnemoon Z, Rahmati Z, et al. Gene Expression and Levels of TGF-B in PBMC Is Associated with Severity of Symptoms in Chronic Heart Failure. Avicenna J Med Biotechnol. 2020;12:132-134 pubmed
Kim N, Kim H, Lee K, Hong Y, Cho J, Choi J, et al. Single-cell RNA sequencing demonstrates the molecular and cellular reprogramming of metastatic lung adenocarcinoma. Nat Commun. 2020;11:2285 pubmed publisher
Freeman Z, Nirschl T, Hovelson D, Johnston R, Engelhardt J, Selby M, et al. A conserved intratumoral regulatory T cell signature identifies 4-1BB as a pan-cancer target. J Clin Invest. 2020;130:1405-1416 pubmed publisher
Wu D, Lv J, Zhao R, Wu Z, Zheng D, Shi J, et al. PSCA is a target of chimeric antigen receptor T cells in gastric cancer. Biomark Res. 2020;8:3 pubmed publisher
Miao L, Qi J, Zhao Q, Wu Q, Wei D, Wei X, et al. Targeting the STING pathway in tumor-associated macrophages regulates innate immune sensing of gastric cancer cells. Theranostics. 2020;10:498-515 pubmed publisher
Welch J, Kaufman T, Stapleton J, Okeoma C. Semen exosomes inhibit HIV infection and HIV-induced proinflammatory cytokine production independent of the activation state of primary lymphocytes. FEBS Lett. 2020;594:695-709 pubmed publisher
Soodgupta D, White L, Yang W, Johnston R, Andrews J, Kohyama M, et al. RAG-Mediated DNA Breaks Attenuate PU.1 Activity in Early B Cells through Activation of a SPIC-BCLAF1 Complex. Cell Rep. 2019;29:829-843.e5 pubmed publisher
Ramien C, Yusko E, Engler J, Gamradt S, Patas K, Schweingruber N, et al. T Cell Repertoire Dynamics during Pregnancy in Multiple Sclerosis. Cell Rep. 2019;29:810-815.e4 pubmed publisher
Tang M, Cheng L, Li F, Wu B, Chen P, Zhan Y, et al. Transcription Factor IRF4 Dysfunction Affects the Immunosuppressive Function of Treg Cells in Patients with Primary Immune Thrombocytopenia. Biomed Res Int. 2019;2019:1050285 pubmed publisher
Netsrithong R, Promnakhon N, Boonkaew B, Vatanashevanopakorn C, Pattanapanyasat K, Wattanapanitch M. Generation of two induced pluripotent stem cell lines (MUSIi011-A and MUSIi011-B) from peripheral blood T lymphocytes of a healthy individual. Stem Cell Res. 2019;39:101487 pubmed publisher
Yang M, Liu Y, Mo B, Xue Y, Ye C, Jiang Y, et al. Helios but not CD226, TIGIT and Foxp3 is a Potential Marker for CD4+ Treg Cells in Patients with Rheumatoid Arthritis. Cell Physiol Biochem. 2019;52:1178-1192 pubmed publisher
Li X, Li D, Shi Q, Huang X, Ju X. Umbilical cord blood‑derived Helios‑positive regulatory T cells promote angiogenesis in acute lymphoblastic leukemia in mice via CCL22 and the VEGFA‑VEGFR2 pathway. Mol Med Rep. 2019;19:4195-4204 pubmed publisher
Iwahori K, Shintani Y, Funaki S, Yamamoto Y, Matsumoto M, Yoshida T, et al. Peripheral T cell cytotoxicity predicts T cell function in the tumor microenvironment. Sci Rep. 2019;9:2636 pubmed publisher
Miragaia R, Gomes T, Chomka A, Jardine L, Riedel A, Hegazy A, et al. Single-Cell Transcriptomics of Regulatory T Cells Reveals Trajectories of Tissue Adaptation. Immunity. 2019;50:493-504.e7 pubmed publisher
Montel Hagen A, Seet C, Li S, Chick B, Zhu Y, Chang P, et al. Organoid-Induced Differentiation of Conventional T Cells from Human Pluripotent Stem Cells. Cell Stem Cell. 2019;24:376-389.e8 pubmed publisher
Ajith A, Portik Dobos V, Nguyen Lefebvre A, Callaway C, Horuzsko D, Kapoor R, et al. HLA-G dimer targets Granzyme B pathway to prolong human renal allograft survival. FASEB J. 2019;33:5220-5236 pubmed publisher
Lopatina T, Favaro E, Grange C, Cedrino M, Ranghino A, Occhipinti S, et al. PDGF enhances the protective effect of adipose stem cell-derived extracellular vesicles in a model of acute hindlimb ischemia. Sci Rep. 2018;8:17458 pubmed publisher
Savage T, Shonts B, Obradovic A, DeWolf S, Lau S, Zuber J, et al. Early expansion of donor-specific Tregs in tolerant kidney transplant recipients. JCI Insight. 2018;3: pubmed publisher
de Boer B, Prick J, Pruis M, Keane P, Imperato M, Jaques J, et al. Prospective Isolation and Characterization of Genetically and Functionally Distinct AML Subclones. Cancer Cell. 2018;34:674-689.e8 pubmed publisher
Meng S, Li L, Zhou M, Jiang W, Niu H, Yang K. Distribution and prognostic value of tumor‑infiltrating T cells in breast cancer. Mol Med Rep. 2018;18:4247-4258 pubmed publisher
Goletz C, Lischke T, Harnack U, Schiele P, Danielczyk A, Rühmann J, et al. Glyco-Engineered Anti-Human Programmed Death-Ligand 1 Antibody Mediates Stronger CD8 T Cell Activation Than Its Normal Glycosylated and Non-Glycosylated Counterparts. Front Immunol. 2018;9:1614 pubmed publisher
Wang L, Zhou D, Ren H, Chen Y. Effects of modified FOLFOX-6 chemotherapy on cellular immune function in patients with gastric cancer. Oncol Lett. 2018;15:8635-8640 pubmed publisher
Wang B, Lin Y, Hu Y, Shan W, Liu S, Xu Y, et al. mTOR inhibition improves the immunomodulatory properties of human bone marrow mesenchymal stem cells by inducing COX-2 and PGE2. Stem Cell Res Ther. 2017;8:292 pubmed publisher
Riner D, Ndombi E, Carter J, Omondi A, Kittur N, Kavere E, et al. Schistosoma mansoni Infection Can Jeopardize the Duration of Protective Levels of Antibody Responses to Immunizations against Hepatitis B and Tetanus Toxoid. PLoS Negl Trop Dis. 2016;10:e0005180 pubmed publisher
Di Marco Barros R, Roberts N, Dart R, Vantourout P, Jandke A, Nussbaumer O, et al. Epithelia Use Butyrophilin-like Molecules to Shape Organ-Specific γδ T Cell Compartments. Cell. 2016;167:203-218.e17 pubmed publisher
Cerny D, Thi Le D, The T, Zuest R, Kg S, Velumani S, et al. Complete human CD1a deficiency on Langerhans cells due to a rare point mutation in the coding sequence. J Allergy Clin Immunol. 2016;138:1709-1712.e11 pubmed publisher
Zhou Y, Li G, Ren J, Wang L, Zhao J, Ning S, et al. Protection of CD4+ T cells from hepatitis C virus infection-associated senescence via ?Np63-miR-181a-Sirt1 pathway. J Leukoc Biol. 2016;100:1201-1211 pubmed
Lima J, Martins C, Nunes G, Sousa M, Branco J, Borrego L. Impact of Labor on Peripheral Blood Maternal T-Cell Subsets and on Regulatory T and B Cells. Reprod Sci. 2017;24:276-284 pubmed publisher
Luo X, Nie J, Wang S, Chen Z, Chen W, Li D, et al. Poly(ADP-ribosyl)ation of FOXP3 Protein Mediated by PARP-1 Protein Regulates the Function of Regulatory T Cells. J Biol Chem. 2015;290:28675-82 pubmed publisher
Zaldivar Fujigaki J, Arroyo Valerio A, Lopez Alvarenga J, Gutiérrez Reyes E, Kershenobich D, Hernández Ruiz J. Alterations in Activation, Cytotoxic Capacity and Trafficking Profile of Peripheral CD8 T Cells in Young Adult Binge Drinkers. PLoS ONE. 2015;10:e0132521 pubmed publisher
Reichwald K, Jørgensen T, Skov S. TL1A increases expression of CD25, LFA-1, CD134 and CD154, and induces IL-22 and GM-CSF production from effector CD4 T-cells. PLoS ONE. 2014;9:e105627 pubmed publisher
Han L, Yang J, Wang X, Wu Q, Yin S, Li Z, et al. The E3 deubiquitinase USP17 is a positive regulator of retinoic acid-related orphan nuclear receptor ?t (ROR?t) in Th17 cells. J Biol Chem. 2014;289:25546-55 pubmed publisher
Ferraro A, D Alise A, Raj T, Asinovski N, Phillips R, Ergun A, et al. Interindividual variation in human T regulatory cells. Proc Natl Acad Sci U S A. 2014;111:E1111-20 pubmed publisher
Chen Y, Chang M, Chen C, Lin H, Cheng W, Chien C. Depletion of regulatory T lymphocytes reverses the imbalance between pro- and anti-tumor immunities via enhancing antigen-specific T cell immune responses. PLoS ONE. 2012;7:e47190 pubmed publisher
Zhang W, Wang J, Shu Y, Tang T, Zhu Z, Xia N, et al. Impaired thymic export and increased apoptosis account for regulatory T cell defects in patients with non-ST segment elevation acute coronary syndrome. J Biol Chem. 2012;287:34157-66 pubmed publisher
product information
Antigen :
CD25
Apps. Abbrev. :
FC
Cat # :
302605
Clone :
BC96
Item :
PE anti-human CD25
Isotype :
Mouse IgG1, κ
Other Names :
Low affinity IL-2R, IL-2R α chain, Tac, p55
Size :
25 tests
Price (USD) :
39 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PE
Application Notes :
Additional reported applications include: immunocytochemistry^3.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA