product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Alexa Fluor® 647 anti-human CD20
catalog :
302318
quantity :
100 tests
price :
265 USD
clonality :
monoclonal
host :
mouse
conjugate :
AF647
clone name :
2H7
reactivity :
human, mouse, rhesus macaque
application :
flow cytometry, immunohistochemistry - frozen section, mass cytometry
more info or order :
citations: 20
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig s2a
Reijm S, Kissel T, Stoeken Rijsbergen G, Slot L, Wortel C, van Dooren H, et al. Cross-reactivity of IgM anti-modified protein antibodies in rheumatoid arthritis despite limited mutational load. Arthritis Res Ther. 2021;23:230 pubmed publisher
  • flow cytometry; human; loading ...; fig 1a
Yue X, Petersen F, Shu Y, Kasper B, Magatsin J, Ahmadi M, et al. Transfer of PBMC From SSc Patients Induces Autoantibodies and Systemic Inflammation in Rag2-/-/IL2rg-/- Mice. Front Immunol. 2021;12:677970 pubmed publisher
  • flow cytometry; human; loading ...
Bohannon C, Ende Z, Cao W, Mboko W, Ranjan P, Kumar A, et al. Influenza Virus Infects and Depletes Activated Adaptive Immune Responders. Adv Sci (Weinh). 2021;8:e2100693 pubmed publisher
  • flow cytometry; human; 1:400; loading ...; fig 3
Turner J, Kim W, Kalaidina E, Goss C, Rauseo A, Schmitz A, et al. SARS-CoV-2 infection induces long-lived bone marrow plasma cells in humans. Nature. 2021;595:421-425 pubmed publisher
  • mass cytometry; human; loading ...; fig 4e
Ingelfinger F, Krishnarajah S, Kramer M, Utz S, Galli E, Lutz M, et al. Single-cell profiling of myasthenia gravis identifies a pathogenic T cell signature. Acta Neuropathol. 2021;141:901-915 pubmed publisher
  • flow cytometry; human; 1:200; loading ...; fig s1h
Biswas S, Mandal G, Payne K, Anadon C, Gatenbee C, Chaurio R, et al. IgA transcytosis and antigen recognition govern ovarian cancer immunity. Nature. 2021;591:464-470 pubmed publisher
  • flow cytometry; mouse; 1:500; loading ...; fig s1b
Gang E, Kim H, Hsieh Y, Ruan Y, Ogana H, Lee S, et al. Integrin α6 mediates the drug resistance of acute lymphoblastic B-cell leukemia. Blood. 2020;136:210-223 pubmed publisher
  • flow cytometry; rhesus macaque; loading ...; fig 2d
Chea L, Wyatt L, Gangadhara S, Moss B, Amara R. Novel Modified Vaccinia Virus Ankara Vector Expressing Anti-apoptotic Gene B13R Delays Apoptosis and Enhances Humoral Responses. J Virol. 2019;93: pubmed publisher
  • flow cytometry; human; loading ...; fig s6d
Bradley T, Peppa D, Pedroza Pacheco I, Li D, Cain D, Henao R, et al. RAB11FIP5 Expression and Altered Natural Killer Cell Function Are Associated with Induction of HIV Broadly Neutralizing Antibody Responses. Cell. 2018;175:387-399.e17 pubmed publisher
  • flow cytometry; human; loading ...; fig 6b
Dam E, Maier A, Hocking A, Carlin J, Buckner J. Increased Binding of Specificity Protein 1 to the IL21R Promoter in B Cells Results in Enhanced B Cell Responses in Rheumatoid Arthritis. Front Immunol. 2018;9:1978 pubmed publisher
  • flow cytometry; human; loading ...; fig 1b
Moysi E, Pallikkuth S, de Armas L, Gonzalez L, Ambrozak D, George V, et al. Altered immune cell follicular dynamics in HIV infection following influenza vaccination. J Clin Invest. 2018;128:3171-3185 pubmed publisher
  • flow cytometry; human; loading ...; fig s2a
Wang L, Shi W, Chappell J, Joyce M, Zhang Y, Kanekiyo M, et al. Importance of Neutralizing Monoclonal Antibodies Targeting Multiple Antigenic Sites on the Middle East Respiratory Syndrome Coronavirus Spike Glycoprotein To Avoid Neutralization Escape. J Virol. 2018;92: pubmed publisher
  • flow cytometry; human; loading ...; fig 1b
Amodio D, Cotugno N, Macchiarulo G, Rocca S, Dimopoulos Y, Castrucci M, et al. Quantitative Multiplexed Imaging Analysis Reveals a Strong Association between Immunogen-Specific B Cell Responses and Tonsillar Germinal Center Immune Dynamics in Children after Influenza Vaccination. J Immunol. 2018;200:538-550 pubmed publisher
Seita Y, Morimura T, Watanabe N, Iwatani C, Tsuchiya H, Nakamura S, et al. Generation of Transgenic Cynomolgus Monkeys Overexpressing the Gene for Amyloid-β Precursor Protein. J Alzheimers Dis. 2020;75:45-60 pubmed publisher
Nerreter T, Letschert S, Götz R, Doose S, Danhof S, Einsele H, et al. Super-resolution microscopy reveals ultra-low CD19 expression on myeloma cells that triggers elimination by CD19 CAR-T. Nat Commun. 2019;10:3137 pubmed publisher
Hsu A, Liu S, Syahirah R, Brasseale K, Wan J, Deng Q. Inducible overexpression of zebrafish microRNA-722 suppresses chemotaxis of human neutrophil like cells. Mol Immunol. 2019;112:206-214 pubmed publisher
Kraig E, Linehan L, Liang H, Romo T, Liu Q, Wu Y, et al. A randomized control trial to establish the feasibility and safety of rapamycin treatment in an older human cohort: Immunological, physical performance, and cognitive effects. Exp Gerontol. 2018;105:53-69 pubmed publisher
Jia B, McNeil L, Dupont C, Tsioris K, Barry R, Scully I, et al. Longitudinal multiparameter single-cell analysis of macaques immunized with pneumococcal protein-conjugated or unconjugated polysaccharide vaccines reveals distinct antigen specific memory B cell repertoires. PLoS ONE. 2017;12:e0183738 pubmed publisher
Tørring C, Petersen C, Bjerg L, Kofod Olsen E, Petersen T, Höllsberg P. The B1-cell subpopulation is diminished in patients with relapsing-remitting multiple sclerosis. J Neuroimmunol. 2013;262:92-9 pubmed publisher
van de Ven A, Compeer E, Bloem A, van de Corput L, van Gijn M, van Montfrans J, et al. Defective calcium signaling and disrupted CD20-B-cell receptor dissociation in patients with common variable immunodeficiency disorders. J Allergy Clin Immunol. 2012;129:755-761.e7 pubmed publisher
product information
Antigen :
CD20
Apps. Abbrev. :
FC, IHC-F
Cat # :
302318
Clone :
2H7
Item :
Alexa Fluor® 647 anti-human CD20
Isotype :
Mouse IgG2b, κ
Other Names :
B1, Bp35
Size :
100 tests
Price (USD) :
265 USD
Reactivity :
Human, Cynomolgus, Rhesus
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
A647
Immunogen :
Human tonsillar B cells
Application Notes :
The epitope recognized by clone 2H7 has been mapped to the sequence YNCEPANPSEKNSPST which lies in the large extracellular loop of human CD20. Additional reported applications (for the relevant formats) include: immunoprecipitation^4 and immunohistochemical staining of acetone-fixed frozen sections^5.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA