product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
TotalSeq™-B0050 anti-human CD19
catalog :
302263
quantity :
10 μg
price :
369 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
HIB19
reactivity :
human, mouse
application :
flow cytometry, mass cytometry
more info or order :
citations: 77
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; fig 4a
Sullivan P, Kumar R, Li W, Hoglund V, Wang L, Zhang Y, et al. FGFR4-Targeted Chimeric Antigen Receptors Combined with Anti-Myeloid Polypharmacy Effectively Treat Orthotopic Rhabdomyosarcoma. Mol Cancer Ther. 2022;21:1608-1621 pubmed publisher
  • flow cytometry; human; loading ...; fig 4j
Brown G, Ca xf1 ete P, Wang H, Medhavy A, Bones J, Roco J, et al. TLR7 gain-of-function genetic variation causes human lupus. Nature. 2022;605:349-356 pubmed publisher
  • flow cytometry; human; loading ...; fig 1f, s1b
Wu X, Xia T, Shin W, Yu K, Jung W, Herrmann A, et al. Viral Mimicry of Interleukin-17A by SARS-CoV-2 ORF8. MBio. 2022;13:e0040222 pubmed publisher
  • flow cytometry; human; 1:100; loading ...; fig 1a
Shen X, Geng R, Li Q, Chen Y, Li S, Wang Q, et al. ACE2-independent infection of T lymphocytes by SARS-CoV-2. Signal Transduct Target Ther. 2022;7:83 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3d
Ecker V, Stumpf M, Brandmeier L, Neumayer T, Pfeuffer L, Engleitner T, et al. Targeted PI3K/AKT-hyperactivation induces cell death in chronic lymphocytic leukemia. Nat Commun. 2021;12:3526 pubmed publisher
  • flow cytometry; human; 1:200; loading ...; fig 3a
Turner J, Kim W, Kalaidina E, Goss C, Rauseo A, Schmitz A, et al. SARS-CoV-2 infection induces long-lived bone marrow plasma cells in humans. Nature. 2021;595:421-425 pubmed publisher
  • flow cytometry; human; loading ...
Martínez Zamudio R, Dewald H, Vasilopoulos T, Gittens Williams L, Fitzgerald Bocarsly P, Herbig U. Senescence-associated β-galactosidase reveals the abundance of senescent CD8+ T cells in aging humans. Aging Cell. 2021;20:e13344 pubmed publisher
  • flow cytometry; human; loading ...
Vavassori V, Mercuri E, Marcovecchio G, Castiello M, Schiroli G, Albano L, et al. Modeling, optimization, and comparable efficacy of T cell and hematopoietic stem cell gene editing for treating hyper-IgM syndrome. EMBO Mol Med. 2021;13:e13545 pubmed publisher
  • flow cytometry; human; loading ...
Hood S, Cosma G, Foulds G, Johnson C, Reeder S, McArdle S, et al. Identifying prostate cancer and its clinical risk in asymptomatic men using machine learning of high dimensional peripheral blood flow cytometric natural killer cell subset phenotyping data. elife. 2020;9: pubmed publisher
  • flow cytometry; human; loading ...; fig 1b
Kim J, Lee J, Go H, Lim J, Oh J, Kim Y, et al. Clinical and histological significance of urinary CD11c+ macrophages in lupus nephritis. Arthritis Res Ther. 2020;22:173 pubmed publisher
  • flow cytometry; human; loading ...; fig st2
Camu W, Mickunas M, Veyrune J, Payan C, Garlanda C, Locati M, et al. Repeated 5-day cycles of low dose aldesleukin in amyotrophic lateral sclerosis (IMODALS): A phase 2a randomised, double-blind, placebo-controlled trial. EBioMedicine. 2020;59:102844 pubmed publisher
  • flow cytometry; human; loading ...; fig 2a
Brouwer P, Caniels T, van der Straten K, Snitselaar J, Aldon Y, Bangaru S, et al. Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability. Science. 2020;369:643-650 pubmed publisher
  • flow cytometry; human; loading ...; fig 4a
Kuhny M, Forbes L, Çakan E, Vega Loza A, Kostiuk V, Dinesh R, et al. Disease-associated CTNNBL1 mutation impairs somatic hypermutation by decreasing nuclear AID. J Clin Invest. 2020;: pubmed publisher
  • flow cytometry; mouse; 1:500; loading ...; fig s1b
Gang E, Kim H, Hsieh Y, Ruan Y, Ogana H, Lee S, et al. Integrin α6 mediates the drug resistance of acute lymphoblastic B-cell leukemia. Blood. 2020;136:210-223 pubmed publisher
  • flow cytometry; human; loading ...; fig 1d
Martin E, Minet N, Boschat A, Sanquer S, Sobrino S, Lenoir C, et al. Impaired lymphocyte function and differentiation in CTPS1-deficient patients result from a hypomorphic homozygous mutation. JCI Insight. 2020;5: pubmed publisher
  • mass cytometry; human; loading ...; fig 1b, 1d, s2
Leylek R, Alcántara Hernández M, Lanzar Z, Lüdtke A, Perez O, Reizis B, et al. Integrated Cross-Species Analysis Identifies a Conserved Transitional Dendritic Cell Population. Cell Rep. 2019;29:3736-3750.e8 pubmed publisher
  • flow cytometry; human; loading ...; fig 1a, 1d
Staniek J, Lorenzetti R, Heller B, Janowska I, Schneider P, Unger S, et al. TRAIL-R1 and TRAIL-R2 Mediate TRAIL-Dependent Apoptosis in Activated Primary Human B Lymphocytes. Front Immunol. 2019;10:951 pubmed publisher
  • flow cytometry; human; loading ...; fig 1a
Terahara K, Iwabuchi R, Hosokawa M, Nishikawa Y, Takeyama H, Takahashi Y, et al. A CCR5+ memory subset within HIV-1-infected primary resting CD4+ T cells is permissive for replication-competent, latently infected viruses in vitro. BMC Res Notes. 2019;12:242 pubmed publisher
  • flow cytometry; human; loading ...; fig s1a
Ye Y, Liu M, Tang L, Du F, Liu Y, Hao P, et al. Iguratimod represses B cell terminal differentiation linked with the inhibition of PKC/EGR1 axis. Arthritis Res Ther. 2019;21:92 pubmed publisher
  • flow cytometry; human; loading ...; fig s8
Pavel Dinu M, Wiebking V, Dejene B, Srifa W, Mantri S, Nicolas C, et al. Gene correction for SCID-X1 in long-term hematopoietic stem cells. Nat Commun. 2019;10:1634 pubmed publisher
  • flow cytometry; human; loading ...; fig s1
Wen Z, Jin K, Shen Y, Yang Z, Li Y, Wu B, et al. N-myristoyltransferase deficiency impairs activation of kinase AMPK and promotes synovial tissue inflammation. Nat Immunol. 2019;20:313-325 pubmed publisher
  • flow cytometry; human; loading ...; fig 5a
Banki Z, Krabbendam L, Klaver D, Leng T, Kruis S, Mehta H, et al. Antibody opsonization enhances MAIT cell responsiveness to bacteria via a TNF-dependent mechanism. Immunol Cell Biol. 2019;97:538-551 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2d
Schlenner S, Pasciuto E, Lagou V, Burton O, Prezzemolo T, Junius S, et al. NFIL3 mutations alter immune homeostasis and sensitise for arthritis pathology. Ann Rheum Dis. 2019;78:342-349 pubmed publisher
Kumar P, Lim A, Hazirah S, Chua C, Ngoh A, Poh S, et al. Single-cell transcriptomics and surface epitope detection in human brain epileptic lesions identifies pro-inflammatory signaling. Nat Neurosci. 2022;: pubmed publisher
Traxel S, Lehmann J, Richard S, Sidorov S, Niggli F, Berger C, et al. Support of BCP-ALL-cells by autologous bone marrow Th-cells involves induction of AID expression but not widespread AID off-target mutagenesis. Cancer Immunol Immunother. 2021;: pubmed publisher
Salzer B, Schueller C, Zajc C, Peters T, Schoeber M, Kovacic B, et al. Engineering AvidCARs for combinatorial antigen recognition and reversible control of CAR function. Nat Commun. 2020;11:4166 pubmed publisher
Morad G, Daisy C, Otu H, Libermann T, Dillon S, Moses M. Cdc42-Dependent Transfer of mir301 from Breast Cancer-Derived Extracellular Vesicles Regulates the Matrix Modulating Ability of Astrocytes at the Blood-Brain Barrier. Int J Mol Sci. 2020;21: pubmed publisher
Wong S, Lenzini S, Cooper M, Mooney D, Shin J. Soft extracellular matrix enhances inflammatory activation of mesenchymal stromal cells to induce monocyte production and trafficking. Sci Adv. 2020;6:eaaw0158 pubmed publisher
Meckiff B, Ladell K, McLaren J, Ryan G, Leese A, James E, et al. Primary EBV Infection Induces an Acute Wave of Activated Antigen-Specific Cytotoxic CD4+ T Cells. J Immunol. 2019;203:1276-1287 pubmed publisher
Ma W, Lee J, Backenroth D, Zhou Y, Bush E, Sims P, et al. Single cell RNA-Seq reveals pre-cDCs fate determined by transcription factor combinatorial dose. BMC Mol Cell Biol. 2019;20:20 pubmed publisher
Canete P, Sweet R, Gonzalez Figueroa P, Papa I, Ohkura N, Bolton H, et al. Regulatory roles of IL-10-producing human follicular T cells. J Exp Med. 2019;: pubmed publisher
Ferdosi S, Ewaisha R, Moghadam F, Krishna S, Park J, Ebrahimkhani M, et al. Multifunctional CRISPR-Cas9 with engineered immunosilenced human T cell epitopes. Nat Commun. 2019;10:1842 pubmed publisher
Luong Gardiol N, Siddiqui I, Pizzitola I, Jeevan Raj B, Charmoy M, Huang Y, et al. γ-Catenin-Dependent Signals Maintain BCR-ABL1+ B Cell Acute Lymphoblastic Leukemia. Cancer Cell. 2019;35:649-663.e10 pubmed publisher
Hammerich L, Marron T, Upadhyay R, Svensson Arvelund J, Dhainaut M, Hussein S, et al. Systemic clinical tumor regressions and potentiation of PD1 blockade with in situ vaccination. Nat Med. 2019;25:814-824 pubmed publisher
Lu E, Wolfreys F, Muppidi J, Xu Y, Cyster J. S-Geranylgeranyl-L-glutathione is a ligand for human B cell-confinement receptor P2RY8. Nature. 2019;: pubmed publisher
Franco L, Gadkari M, Howe K, Sun J, Kardava L, Kumar P, et al. Immune regulation by glucocorticoids can be linked to cell type-dependent transcriptional responses. J Exp Med. 2019;216:384-406 pubmed publisher
Faliti C, Gualtierotti R, Rottoli E, Gerosa M, Perruzza L, Romagnani A, et al. P2X7 receptor restrains pathogenic Tfh cell generation in systemic lupus erythematosus. J Exp Med. 2019;216:317-336 pubmed publisher
Furie R, Werth V, Merola J, Stevenson L, Reynolds T, Naik H, et al. Monoclonal antibody targeting BDCA2 ameliorates skin lesions in systemic lupus erythematosus. J Clin Invest. 2019;129:1359-1371 pubmed publisher
Rataj F, Jacobi S, Stoiber S, Asang F, Ogonek J, Tokarew N, et al. High-affinity CD16-polymorphism and Fc-engineered antibodies enable activity of CD16-chimeric antigen receptor-modified T cells for cancer therapy. Br J Cancer. 2019;120:79-87 pubmed publisher
Bradley T, Peppa D, Pedroza Pacheco I, Li D, Cain D, Henao R, et al. RAB11FIP5 Expression and Altered Natural Killer Cell Function Are Associated with Induction of HIV Broadly Neutralizing Antibody Responses. Cell. 2018;175:387-399.e17 pubmed publisher
Jelcić I, Al Nimer F, Wang J, Lentsch V, Planas R, Jelcic I, et al. Memory B Cells Activate Brain-Homing, Autoreactive CD4+ T Cells in Multiple Sclerosis. Cell. 2018;175:85-100.e23 pubmed publisher
Achita P, Dervović D, Ly D, Lee J, Haug T, Joe B, et al. Infusion of ex-vivo expanded human TCR-αβ+ double-negative regulatory T cells delays onset of xenogeneic graft-versus-host disease. Clin Exp Immunol. 2018;193:386-399 pubmed publisher
Kim S, Choi J, Laínez B, Schulz V, Karas D, Baum E, et al. Human Extrafollicular CD4+ Th Cells Help Memory B Cells Produce Igs. J Immunol. 2018;201:1359-1372 pubmed publisher
Noto A, Procopio F, Banga R, Suffiotti M, Corpataux J, Cavassini M, et al. CD32+ and PD-1+ Lymph Node CD4 T Cells Support Persistent HIV-1 Transcription in Treated Aviremic Individuals. J Virol. 2018;92: pubmed publisher
Moysi E, Pallikkuth S, de Armas L, Gonzalez L, Ambrozak D, George V, et al. Altered immune cell follicular dynamics in HIV infection following influenza vaccination. J Clin Invest. 2018;128:3171-3185 pubmed publisher
Kiener R, Fleischmann M, Wiegand M, Lemmermann N, Schwegler C, Kaufmann C, et al. Efficient Delivery of Human Cytomegalovirus T Cell Antigens by Attenuated Sendai Virus Vectors. J Virol. 2018;92: pubmed publisher
Risnes L, Christophersen A, Dahal Koirala S, Neumann R, Sandve G, Sarna V, et al. Disease-driving CD4+ T cell clonotypes persist for decades in celiac disease. J Clin Invest. 2018;128:2642-2650 pubmed publisher
He X, Kläsener K, Iype J, Becker M, Maity P, Cavallari M, et al. Continuous signaling of CD79b and CD19 is required for the fitness of Burkitt lymphoma B cells. EMBO J. 2018;37: pubmed publisher
Panda S, Facchinetti V, Voynova E, Hanabuchi S, Karnell J, Hanna R, et al. Galectin-9 inhibits TLR7-mediated autoimmunity in murine lupus models. J Clin Invest. 2018;128:1873-1887 pubmed publisher
Murray L, Satti I, Meyerowitz J, Jones M, Willberg C, Ussher J, et al. Human Immunodeficiency Virus Infection Impairs Th1 and Th17 Mycobacterium tuberculosis-Specific T-Cell Responses. J Infect Dis. 2018;217:1782-1792 pubmed publisher
Miles J, Tan M, Dolton G, Edwards E, Galloway S, Laugel B, et al. Peptide mimic for influenza vaccination using nonnatural combinatorial chemistry. J Clin Invest. 2018;128:1569-1580 pubmed publisher
Vanshylla K, Bartsch C, Hitzing C, Krümpelmann L, Wienands J, Engels N. Grb2 and GRAP connect the B cell antigen receptor to Erk MAP kinase activation in human B cells. Sci Rep. 2018;8:4244 pubmed publisher
Wagstaffe H, Nielsen C, Riley E, Goodier M. IL-15 Promotes Polyfunctional NK Cell Responses to Influenza by Boosting IL-12 Production. J Immunol. 2018;200:2738-2747 pubmed publisher
Rius C, Attaf M, Tungatt K, Bianchi V, Legut M, Bovay A, et al. Peptide-MHC Class I Tetramers Can Fail To Detect Relevant Functional T Cell Clonotypes and Underestimate Antigen-Reactive T Cell Populations. J Immunol. 2018;200:2263-2279 pubmed publisher
Böiers C, Richardson S, Laycock E, Zriwil A, Turati V, Brown J, et al. A Human IPS Model Implicates Embryonic B-Myeloid Fate Restriction as Developmental Susceptibility to B Acute Lymphoblastic Leukemia-Associated ETV6-RUNX1. Dev Cell. 2018;44:362-377.e7 pubmed publisher
Bujko A, Atlasy N, Landsverk O, Richter L, Yaqub S, Horneland R, et al. Transcriptional and functional profiling defines human small intestinal macrophage subsets. J Exp Med. 2018;215:441-458 pubmed publisher
Tsuda B, Miyamoto A, Yokoyama K, Ogiya R, Oshitanai R, Terao M, et al. B-cell populations are expanded in breast cancer patients compared with healthy controls. Breast Cancer. 2018;25:284-291 pubmed publisher
Renand A, Shamji M, Harris K, Qin T, Wambre E, Scadding G, et al. Synchronous immune alterations mirror clinical response during allergen immunotherapy. J Allergy Clin Immunol. 2018;141:1750-1760.e1 pubmed publisher
Pinder C, Kratochvil S, Cizmeci D, Muir L, Guo Y, Shattock R, et al. Isolation and Characterization of Antigen-Specific Plasmablasts Using a Novel Flow Cytometry-Based Ig Capture Assay. J Immunol. 2017;199:4180-4188 pubmed publisher
Catalan Dibene J, Vazquez M, Luu V, Nuccio S, Karimzadeh A, Kastenschmidt J, et al. Identification of IL-40, a Novel B Cell-Associated Cytokine. J Immunol. 2017;199:3326-3335 pubmed publisher
Li J, Bhattacharya S, Zhou J, Phadnis Moghe A, Crawford R, Kaminski N. Aryl Hydrocarbon Receptor Activation Suppresses EBF1 and PAX5 and Impairs Human B Lymphopoiesis. J Immunol. 2017;199:3504-3515 pubmed publisher
Marras F, Casabianca A, Bozzano F, Ascierto M, Orlandi C, Di Biagio A, et al. Control of the HIV-1 DNA Reservoir Is Associated In Vivo and In Vitro with NKp46/NKp30 (CD335 CD337) Inducibility and Interferon Gamma Production by Transcriptionally Unique NK Cells. J Virol. 2017;91: pubmed publisher
den Hartog G, van Osch T, Vos M, Meijer B, Savelkoul H, van Neerven R, et al. BAFF augments IgA2 and IL-10 production by TLR7/8 stimulated total peripheral blood B cells. Eur J Immunol. 2018;48:283-292 pubmed publisher
Teigler J, Zelinskyy G, Eller M, Bolton D, Marovich M, Gordon A, et al. Differential Inhibitory Receptor Expression on T Cells Delineates Functional Capacities in Chronic Viral Infection. J Virol. 2017;91: pubmed publisher
Arkatkar T, Du S, Jacobs H, Dam E, Hou B, Buckner J, et al. B cell-derived IL-6 initiates spontaneous germinal center formation during systemic autoimmunity. J Exp Med. 2017;214:3207-3217 pubmed publisher
Zhang Y, Kurupati R, Liu L, Zhou X, Zhang G, Hudaihed A, et al. Enhancing CD8+ T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy. Cancer Cell. 2017;32:377-391.e9 pubmed publisher
Schwerd T, Twigg S, Aschenbrenner D, Manrique S, Miller K, Taylor I, et al. A biallelic mutation in IL6ST encoding the GP130 co-receptor causes immunodeficiency and craniosynostosis. J Exp Med. 2017;214:2547-2562 pubmed publisher
McHugh D, Caduff N, Barros M, Rämer P, Raykova A, Murer A, et al. Persistent KSHV Infection Increases EBV-Associated Tumor Formation In Vivo via Enhanced EBV Lytic Gene Expression. Cell Host Microbe. 2017;22:61-73.e7 pubmed publisher
Mou W, Han W, Ma X, Wang X, Qin H, Zhao W, et al. γδTFH cells promote B cell maturation and antibody production in neuroblastoma. BMC Immunol. 2017;18:36 pubmed publisher
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Patel A, Zhang Y, Fullerton J, Boelen L, Rongvaux A, Maini A, et al. The fate and lifespan of human monocyte subsets in steady state and systemic inflammation. J Exp Med. 2017;214:1913-1923 pubmed publisher
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Lopes F, Bálint Å, Valvo S, Felce J, Hessel E, Dustin M, et al. Membrane nanoclusters of FcγRI segregate from inhibitory SIRPα upon activation of human macrophages. J Cell Biol. 2017;216:1123-1141 pubmed publisher
Vander Heiden J, Stathopoulos P, Zhou J, Chen L, Gilbert T, Bolen C, et al. Dysregulation of B Cell Repertoire Formation in Myasthenia Gravis Patients Revealed through Deep Sequencing. J Immunol. 2017;198:1460-1473 pubmed publisher
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Guo H, Cranert S, Lu Y, Zhong M, Zhang S, Chen J, et al. Deletion of Slam locus in mice reveals inhibitory role of SLAM family in NK cell responses regulated by cytokines and LFA-1. J Exp Med. 2016;213:2187-207 pubmed publisher
Lewis M, Vyse S, Shields A, Boeltz S, Gordon P, Spector T, et al. UBE2L3 polymorphism amplifies NF-κB activation and promotes plasma cell development, linking linear ubiquitination to multiple autoimmune diseases. Am J Hum Genet. 2015;96:221-34 pubmed publisher
product information
Antigen :
CD19
Apps. Abbrev. :
PG
Cat # :
302263
Clone :
HIB19
Item :
TotalSeq™-B0050 anti-human CD19
Isotype :
Mouse IgG1, κ
Other Names :
B4
Size :
10 μg
Price (USD) :
369 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
TOTALSEQ_B
Application Notes :
Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections^8 and blocking of B cell proliferation. Clone HIB19 is not recommended for formalin-fixed paraffin-embedded sections. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 302267 & 302268).; Clone HIB19 partially blocks anti-human CD19 clones 4G7 and SJ25C1 staining based on in-house testing;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA