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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PE anti-human CD19
catalog :
302254
quantity :
100 μg
price :
73 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
HIB19
reactivity :
human, mouse
application :
flow cytometry
more info or order :
citations: 55
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; fig 4a
Sullivan P, Kumar R, Li W, Hoglund V, Wang L, Zhang Y, et al. FGFR4-Targeted Chimeric Antigen Receptors Combined with Anti-Myeloid Polypharmacy Effectively Treat Orthotopic Rhabdomyosarcoma. Mol Cancer Ther. 2022;21:1608-1621 pubmed publisher
  • flow cytometry; human; 1:400; loading ...
Amanat F, Thapa M, Lei T, Ahmed S, Adelsberg D, Carreño J, et al. SARS-CoV-2 mRNA vaccination induces functionally diverse antibodies to NTD, RBD, and S2. Cell. 2021;184:3936-3948.e10 pubmed publisher
  • flow cytometry; human; 1:200; fig 3a
Turner J, Kim W, Kalaidina E, Goss C, Rauseo A, Schmitz A, et al. SARS-CoV-2 infection induces long-lived bone marrow plasma cells in humans. Nature. 2021;595:421-425 pubmed publisher
  • flow cytometry; mouse; 1:500; loading ...; fig s1b
Gang E, Kim H, Hsieh Y, Ruan Y, Ogana H, Lee S, et al. Integrin α6 mediates the drug resistance of acute lymphoblastic B-cell leukemia. Blood. 2020;136:210-223 pubmed publisher
  • flow cytometry; human; loading ...; fig s1a
Lopes F, Bálint Å, Valvo S, Felce J, Hessel E, Dustin M, et al. Membrane nanoclusters of FcγRI segregate from inhibitory SIRPα upon activation of human macrophages. J Cell Biol. 2017;216:1123-1141 pubmed publisher
Mudd P, Minervina A, Pogorelyy M, Turner J, Kim W, Kalaidina E, et al. SARS-CoV-2 mRNA vaccination elicits a robust and persistent T follicular helper cell response in humans. Cell. 2022;185:603-613.e15 pubmed publisher
Ruan Y, Kim H, Ogana H, Gang E, Li S, Liu H, et al. In vitro and in vivo effects of AVA4746, a novel competitive antagonist of the ligand binding of VLA-4, in B-cell acute lymphoblastic leukemia. Exp Ther Med. 2022;23:47 pubmed publisher
Yu H, Yang W, Huang J, Miao X, Wang B, Ren X, et al. GPR120 induces regulatory dendritic cells by inhibiting HK2-dependent glycolysis to alleviate fulminant hepatic failure. Cell Death Dis. 2021;13:1 pubmed publisher
Wang X, Wu P, Li X, Zeng C, Zhu J, Zhou Y, et al. Extracellular Vesicles Inhibit Proliferation and Invasion of Ovarian Endometrial Stromal Cells and Their Expression of SF-1, ERβ, and Aromatase. Front Endocrinol (Lausanne). 2021;12:666195 pubmed publisher
Vora A, Mondala P, Costello C, MacLeod A, Crews L. Sensitive intranuclear flow cytometric quantification of IRF4 protein in multiple myeloma and normal human hematopoietic cells. STAR Protoc. 2021;2:100565 pubmed publisher
Caduff N, McHugh D, Rieble L, Forconi C, Ong echa J, Oluoch P, et al. KSHV infection drives poorly cytotoxic CD56-negative natural killer cell differentiation in vivo upon KSHV/EBV dual infection. Cell Rep. 2021;35:109056 pubmed publisher
Richardson S, Ghazanfari R, Chhetri J, Enver T, Böiers C. In vitro differentiation of human pluripotent stem cells into the B lineage using OP9-MS5 co-culture. STAR Protoc. 2021;2:100420 pubmed publisher
de Jonge K, Tillé L, Lourenço J, Maby El Hajjami H, Nassiri S, Racle J, et al. Inflammatory B cells correlate with failure to checkpoint blockade in melanoma patients. Oncoimmunology. 2021;10:1873585 pubmed publisher
Lu P, Wang S, Franzen C, Venkataraman G, McClure R, Li L, et al. Ibrutinib and venetoclax target distinct subpopulations of CLL cells: implication for residual disease eradication. Blood Cancer J. 2021;11:39 pubmed publisher
Japp A, Meng W, Rosenfeld A, Perry D, Thirawatananond P, Bacher R, et al. TCR+/BCR+ dual-expressing cells and their associated public BCR clonotype are not enriched in type 1 diabetes. Cell. 2021;184:827-839.e14 pubmed publisher
Abdul Jawad S, Baù L, Alaguthurai T, Del Molino Del Barrio I, Laing A, Hayday T, et al. Acute Immune Signatures and Their Legacies in Severe Acute Respiratory Syndrome Coronavirus-2 Infected Cancer Patients. Cancer Cell. 2021;39:257-275.e6 pubmed publisher
Mondala P, Vora A, Zhou T, Lazzari E, Ladel L, Luo X, et al. Selective antisense oligonucleotide inhibition of human IRF4 prevents malignant myeloma regeneration via cell cycle disruption. Cell Stem Cell. 2021;28:623-636.e9 pubmed publisher
Wang J, Xu Y, Chen Z, Liang J, Lin Z, Liang H, et al. Liver Immune Profiling Reveals Pathogenesis and Therapeutics for Biliary Atresia. Cell. 2020;183:1867-1883.e26 pubmed publisher
Kreye J, Reincke S, Kornau H, Sánchez Sendin E, Corman V, Liu H, et al. A Therapeutic Non-self-reactive SARS-CoV-2 Antibody Protects from Lung Pathology in a COVID-19 Hamster Model. Cell. 2020;183:1058-1069.e19 pubmed publisher
Kan S, Bito T, Shimabuku M, Taguchi J, Ohkusa T, Shimodaira S, et al. Impact of mature dendritic cells pulsed with a novel WT1 helper peptide on the induction of HLA‑A2‑restricted WT1‑reactive CD8+ T cells. Int J Oncol. 2020;57:1047-1056 pubmed publisher
Frame J, Kubaczka C, Long T, Esain V, Soto R, Hachimi M, et al. Metabolic Regulation of Inflammasome Activity Controls Embryonic Hematopoietic Stem and Progenitor Cell Production. Dev Cell. 2020;: pubmed publisher
Laing A, Lorenc A, Del Molino Del Barrio I, Das A, Fish M, Monin L, et al. A dynamic COVID-19 immune signature includes associations with poor prognosis. Nat Med. 2020;26:1623-1635 pubmed publisher
Li W, Qiu S, Chen J, Jiang S, Chen W, Jiang J, et al. Chimeric Antigen Receptor Designed to Prevent Ubiquitination and Downregulation Showed Durable Antitumor Efficacy. Immunity. 2020;53:456-470.e6 pubmed publisher
Lavaert M, Liang K, Vandamme N, Park J, Roels J, Kowalczyk M, et al. Integrated scRNA-Seq Identifies Human Postnatal Thymus Seeding Progenitors and Regulatory Dynamics of Differentiating Immature Thymocytes. Immunity. 2020;52:1088-1104.e6 pubmed publisher
Jackson Jones L, Smith P, Portman J, Magalhaes M, Mylonas K, Vermeren M, et al. Stromal Cells Covering Omental Fat-Associated Lymphoid Clusters Trigger Formation of Neutrophil Aggregates to Capture Peritoneal Contaminants. Immunity. 2020;52:700-715.e6 pubmed publisher
Sanchez H, Moroney J, Gan H, Shen T, Im J, Li T, et al. B cell-intrinsic epigenetic modulation of antibody responses by dietary fiber-derived short-chain fatty acids. Nat Commun. 2020;11:60 pubmed publisher
Chabi S, Uzan B, Naguibneva I, Rucci J, Fahy L, Calvo J, et al. Hypoxia Regulates Lymphoid Development of Human Hematopoietic Progenitors. Cell Rep. 2019;29:2307-2320.e6 pubmed publisher
Huang Y, Mouttet B, Warnatz H, Risch T, Rietmann F, Frommelt F, et al. The Leukemogenic TCF3-HLF Complex Rewires Enhancers Driving Cellular Identity and Self-Renewal Conferring EP300 Vulnerability. Cancer Cell. 2019;36:630-644.e9 pubmed publisher
Serra Peinado C, Grau Expósito J, Luque Ballesteros L, Astorga Gamaza A, Navarro J, Gallego Rodriguez J, et al. Expression of CD20 after viral reactivation renders HIV-reservoir cells susceptible to Rituximab. Nat Commun. 2019;10:3705 pubmed publisher
Cho A, Caldara A, Ran N, Menne Z, Kauffman R, Affer M, et al. Single-Cell Analysis Suggests that Ongoing Affinity Maturation Drives the Emergence of Pemphigus Vulgaris Autoimmune Disease. Cell Rep. 2019;28:909-922.e6 pubmed publisher
Dangaj D, Bruand M, Grimm A, Ronet C, Barras D, Duttagupta P, et al. Cooperation between Constitutive and Inducible Chemokines Enables T Cell Engraftment and Immune Attack in Solid Tumors. Cancer Cell. 2019;35:885-900.e10 pubmed publisher
Zumaquero E, Stone S, Scharer C, Jenks S, Nellore A, Mousseau B, et al. IFNγ induces epigenetic programming of human T-bethi B cells and promotes TLR7/8 and IL-21 induced differentiation. elife. 2019;8: pubmed publisher
Luong Gardiol N, Siddiqui I, Pizzitola I, Jeevan Raj B, Charmoy M, Huang Y, et al. γ-Catenin-Dependent Signals Maintain BCR-ABL1+ B Cell Acute Lymphoblastic Leukemia. Cancer Cell. 2019;35:649-663.e10 pubmed publisher
Zhang F, Li R, Yang Y, Shi C, Shen Y, Lu C, et al. Specific Decrease in B-Cell-Derived Extracellular Vesicles Enhances Post-Chemotherapeutic CD8+ T Cell Responses. Immunity. 2019;50:738-750.e7 pubmed publisher
Greiner V, Bou Puerto R, Liu S, Herbel C, Carmona E, Goldberg M. CRISPR-Mediated Editing of the B Cell Receptor in Primary Human B Cells. iScience. 2019;12:369-378 pubmed publisher
Xiao X, Lai W, Xie H, Liu Y, Guo W, Liu Y, et al. Targeting JNK pathway promotes human hematopoietic stem cell expansion. Cell Discov. 2019;5:2 pubmed publisher
Jiang Q, Isquith J, Zipeto M, Diep R, Pham J, Delos Santos N, et al. Hyper-Editing of Cell-Cycle Regulatory and Tumor Suppressor RNA Promotes Malignant Progenitor Propagation. Cancer Cell. 2019;35:81-94.e7 pubmed publisher
Velázquez Avila M, Balandrán J, Ramírez Ramírez D, Velázquez Avila M, Sandoval A, Felipe López A, et al. High cortactin expression in B-cell acute lymphoblastic leukemia is associated with increased transendothelial migration and bone marrow relapse. Leukemia. 2019;33:1337-1348 pubmed publisher
Saraiva D, Jacinto A, Borralho P, Braga S, Cabral M. HLA-DR in Cytotoxic T Lymphocytes Predicts Breast Cancer Patients' Response to Neoadjuvant Chemotherapy. Front Immunol. 2018;9:2605 pubmed publisher
He W, Holtkamp S, Hergenhan S, Kraus K, De Juan A, Weber J, et al. Circadian Expression of Migratory Factors Establishes Lineage-Specific Signatures that Guide the Homing of Leukocyte Subsets to Tissues. Immunity. 2018;49:1175-1190.e7 pubmed publisher
Gomes A, Kurochkin I, Chang B, DANIEL M, Law K, Satija N, et al. Cooperative Transcription Factor Induction Mediates Hemogenic Reprogramming. Cell Rep. 2018;25:2821-2835.e7 pubmed publisher
Kagoya Y, Nakatsugawa M, Saso K, Guo T, Anczurowski M, Wang C, et al. DOT1L inhibition attenuates graft-versus-host disease by allogeneic T cells in adoptive immunotherapy models. Nat Commun. 2018;9:1915 pubmed publisher
Palazzo A, Herter S, Grosmaire L, Jones R, Frey C, Limani F, et al. The PI3Kδ-Selective Inhibitor Idelalisib Minimally Interferes with Immune Effector Function Mediated by Rituximab or Obinutuzumab and Significantly Augments B Cell Depletion In Vivo. J Immunol. 2018;200:2304-2312 pubmed publisher
Böiers C, Richardson S, Laycock E, Zriwil A, Turati V, Brown J, et al. A Human IPS Model Implicates Embryonic B-Myeloid Fate Restriction as Developmental Susceptibility to B Acute Lymphoblastic Leukemia-Associated ETV6-RUNX1. Dev Cell. 2018;44:362-377.e7 pubmed publisher
Basnett J, Xie V, Cisterne A, Bradstock K, Bendall L. Regulation of the bone marrow microenvironment by G-CSF: Effects of G-CSF on acute lymphoblastic leukaemia. PLoS ONE. 2017;12:e0188042 pubmed publisher
Theurich S, Tsaousidou E, Hanssen R, Lempradl A, Mauer J, Timper K, et al. IL-6/Stat3-Dependent Induction of a Distinct, Obesity-Associated NK Cell Subpopulation Deteriorates Energy and Glucose Homeostasis. Cell Metab. 2017;26:171-184.e6 pubmed publisher
Joly P, Schaus T, Sass A, Dienelt A, Cheung A, Duda G, et al. Biophysical induction of cell release for minimally manipulative cell enrichment strategies. PLoS ONE. 2017;12:e0180568 pubmed publisher
Newberry S, Prechsl U, Pace M, Kahmen A. Tightly bound soil water introduces isotopic memory effects on mobile and extractable soil water pools. Isotopes Environ Health Stud. 2017;53:368-381 pubmed publisher
Woodberry T, Loughland J, Minigo G, Burel J, Amante F, Piera K, et al. Early Immune Regulatory Changes in a Primary Controlled Human Plasmodium vivax Infection: CD1c+ Myeloid Dendritic Cell Maturation Arrest, Induction of the Kynurenine Pathway, and Regulatory T Cell Activation. Infect Immun. 2017;85: pubmed publisher
McComb S, Aguadé Gorgorió J, Harder L, Marovca B, Cario G, Eckert C, et al. Activation of concurrent apoptosis and necroptosis by SMAC mimetics for the treatment of refractory and relapsed ALL. Sci Transl Med. 2016;8:339ra70 pubmed publisher
Bigler M, Egli S, Hysek C, Hoenger G, Schmied L, Baldin F, et al. Stress-Induced In Vivo Recruitment of Human Cytotoxic Natural Killer Cells Favors Subsets with Distinct Receptor Profiles and Associates with Increased Epinephrine Levels. PLoS ONE. 2015;10:e0145635 pubmed publisher
Matsui K, Adelsberger J, Kemp T, Baseler M, Ledgerwood J, Pinto L. Circulating CXCR5⁺CD4⁺ T Follicular-Like Helper Cell and Memory B Cell Responses to Human Papillomavirus Vaccines. PLoS ONE. 2015;10:e0137195 pubmed publisher
Collison J, Carlin L, Eichmann M, Geissmann F, Peakman M. Heterogeneity in the Locomotory Behavior of Human Monocyte Subsets over Human Vascular Endothelium In Vitro. J Immunol. 2015;195:1162-70 pubmed publisher
White C, Pone E, Lam T, Tat C, Hayama K, Li G, et al. Histone deacetylase inhibitors upregulate B cell microRNAs that silence AID and Blimp-1 expression for epigenetic modulation of antibody and autoantibody responses. J Immunol. 2014;193:5933-50 pubmed publisher
Yamanaka M, Kato Y, Angata T, Narimatsu H. Deletion polymorphism of SIGLEC14 and its functional implications. Glycobiology. 2009;19:841-6 pubmed publisher
product information
Antigen :
CD19
Apps. Abbrev. :
FC
Cat # :
302254
Clone :
HIB19
Item :
PE anti-human CD19
Isotype :
Mouse IgG1, κ
Other Names :
B4
Size :
100 μg
Price (USD) :
73 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PE
Application Notes :
Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections^8 and blocking of B cell proliferation. Clone HIB19 is not recommended for formalin-fixed paraffin-embedded sections. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 302267 & 302268).; Clone HIB19 partially blocks anti-human CD19 clones 4G7 and SJ25C1 staining based on in-house testing;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA