product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Brilliant Violet 421™ anti-human CD19
catalog :
302234
quantity :
100 tests
price :
381 USD
clonality :
monoclonal
host :
mouse
conjugate :
BV421
clone name :
HIB19
reactivity :
human
application :
immunocytochemistry, flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 52
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 1a, 1d
Staniek J, Lorenzetti R, Heller B, Janowska I, Schneider P, Unger S, et al. TRAIL-R1 and TRAIL-R2 Mediate TRAIL-Dependent Apoptosis in Activated Primary Human B Lymphocytes. Front Immunol. 2019;10:951 pubmed publisher
  • flow cytometry; human; 1:200; loading ...; fig 2c
Zumaquero E, Stone S, Scharer C, Jenks S, Nellore A, Mousseau B, et al. IFNγ induces epigenetic programming of human T-bethi B cells and promotes TLR7/8 and IL-21 induced differentiation. elife. 2019;8: pubmed publisher
  • flow cytometry; human; loading ...; fig 6a
Vanshylla K, Bartsch C, Hitzing C, Krümpelmann L, Wienands J, Engels N. Grb2 and GRAP connect the B cell antigen receptor to Erk MAP kinase activation in human B cells. Sci Rep. 2018;8:4244 pubmed publisher
  • flow cytometry; human; fig 1a
Amara K, Clay E, Yeo L, Ramsköld D, Spengler J, Sippl N, et al. B cells expressing the IgA receptor FcRL4 participate in the autoimmune response in patients with rheumatoid arthritis. J Autoimmun. 2017;81:34-43 pubmed publisher
Takeshita M, Fukuyama H, Kamada K, Matsumoto T, Makino Okamura C, Lin Q, et al. Potent neutralizing broad-spectrum antibody against SARS-CoV-2 generated from dual-antigen-specific B cells from convalescents. iScience. 2023;26:106955 pubmed publisher
Garc xed a Vega M, Melgoza Gonz xe1 lez E, Hern xe1 ndez Valenzuela S, Hinojosa Trujillo D, Res xe9 ndiz Sandoval M, Llamas Covarrubias M, et al. 19n01, a broadly neutralizing antibody against omicron BA.1, BA.2, BA.4/5, and other SARS-CoV-2 variants of concern. iScience. 2023;26:106562 pubmed publisher
Chauvin C, Levillayer L, Roumier M, Nielly H, Roth C, Karnam A, et al. Tocilizumab-treated convalescent COVID-19 patients retain the cross-neutralization potential against SARS-CoV-2 variants. iScience. 2023;26:106124 pubmed publisher
Ringelstein Harlev S, Fanadka M, Horowitz N, Bettman N, Katz T. In chronic lymphocytic leukemia, activation of the thrombopoietin receptor promotes T-cell inhibitory properties, contributing to immunosuppression. Eur J Haematol. 2023;110:371-378 pubmed publisher
De Hert E, Verboven K, Wouters K, Jocken J, De Meester I. Prolyl Carboxypeptidase Activity Is Present in Human Adipose Tissue and Is Elevated in Serum of Obese Men with Type 2 Diabetes. Int J Mol Sci. 2022;23: pubmed publisher
Asashima H, Axisa P, Pham T, Longbrake E, Ruff W, Lele N, et al. Impaired TIGIT expression on B cells drives circulating follicular helper T cell expansion in multiple sclerosis. J Clin Invest. 2022;132: pubmed publisher
Sun Q, Wang Y, Ji H, Sun X, Xie S, Chen L, et al. Lenvatinib for effectively treating antiangiogenic drug-resistant nasopharyngeal carcinoma. Cell Death Dis. 2022;13:724 pubmed publisher
Barnes C, Schoofs T, Gnanapragasam P, Golijanin J, Huey Tubman K, Gruell H, et al. A naturally arising broad and potent CD4-binding site antibody with low somatic mutation. Sci Adv. 2022;8:eabp8155 pubmed publisher
Beaudoin Bussieres G, Arduini A, Bourassa C, Medjahed H, Gendron Lepage G, Richard J, et al. SARS-CoV-2 Accessory Protein ORF8 Decreases Antibody-Dependent Cellular Cytotoxicity. Viruses. 2022;14: pubmed publisher
Zheng H, Chen Y, Li J, Li H, Zhao X, Li J, et al. Longitudinal analyses reveal distinct immune response landscapes in lung and intestinal tissues from SARS-CoV-2-infected rhesus macaques. Cell Rep. 2022;39:110864 pubmed publisher
Studniberg S, Ioannidis L, Utami R, Trianty L, Liao Y, Abeysekera W, et al. Molecular profiling reveals features of clinical immunity and immunosuppression in asymptomatic P. falciparum malaria. Mol Syst Biol. 2022;18:e10824 pubmed publisher
Tian P, Elefanty A, Stanley E, Durnall J, Thompson L, Elwood N. Creation of GMP-Compliant iPSCs From Banked Umbilical Cord Blood. Front Cell Dev Biol. 2022;10:835321 pubmed publisher
Vijayakumar B, Boustani K, Ogger P, Papadaki A, Tonkin J, Orton C, et al. Immuno-proteomic profiling reveals aberrant immune cell regulation in the airways of individuals with ongoing post-COVID-19 respiratory disease. Immunity. 2022;55:542-556.e5 pubmed publisher
Frensch M, Jäger C, Müller P, Tadić A, Wilhelm I, Wehrum S, et al. Bacterial lectin BambL acts as a B cell superantigen. Cell Mol Life Sci. 2021;78:8165-8186 pubmed publisher
de Silva T, Liu G, Lindsey B, Dong D, Moore S, Hsu N, et al. The impact of viral mutations on recognition by SARS-CoV-2 specific T cells. iScience. 2021;24:103353 pubmed publisher
Nakano M, Ayano M, Kushimoto K, Kawano S, Higashioka K, Inokuchi S, et al. Increased Proportion of CD226+ B Cells Is Associated With the Disease Activity and Prognosis of Systemic Lupus Erythematosus. Front Immunol. 2021;12:713225 pubmed publisher
Hegewisch Solloa E, Seo S, Mundy Bosse B, Mishra A, Waldman E, Maurrasse S, et al. Differential Integrin Adhesome Expression Defines Human NK Cell Residency and Developmental Stage. J Immunol. 2021;207:950-965 pubmed publisher
Turner J, O Halloran J, Kalaidina E, Kim W, Schmitz A, Zhou J, et al. SARS-CoV-2 mRNA vaccines induce persistent human germinal centre responses. Nature. 2021;596:109-113 pubmed publisher
Mimitou E, Lareau C, Chen K, Zorzetto Fernandes A, Hao Y, Takeshima Y, et al. Scalable, multimodal profiling of chromatin accessibility, gene expression and protein levels in single cells. Nat Biotechnol. 2021;39:1246-1258 pubmed publisher
Rossignol E, Dugast A, Compere H, Cottrell C, Copps J, Lin S, et al. Mining HIV controllers for broad and functional antibodies to recognize and eliminate HIV-infected cells. Cell Rep. 2021;35:109167 pubmed publisher
Hohmann M, Habiel D, Espíndola M, Huang G, Jones I, Narayanan R, et al. Antibody-mediated depletion of CCR10+EphA3+ cells ameliorates fibrosis in IPF. JCI Insight. 2021;6: pubmed publisher
Cizmeci D, Lofano G, Rossignol E, Dugast A, Kim D, Cavet G, et al. Distinct clonal evolution of B-cells in HIV controllers with neutralizing antibody breadth. elife. 2021;10: pubmed publisher
Caeser R, Gao J, Di Re M, Gong C, Hodson D. Genetic manipulation and immortalized culture of ex vivo primary human germinal center B cells. Nat Protoc. 2021;16:2499-2519 pubmed publisher
Panwar B, Schmiedel B, Liang S, White B, Rodriguez E, Kalunian K, et al. Multi-cell type gene coexpression network analysis reveals coordinated interferon response and cross-cell type correlations in systemic lupus erythematosus. Genome Res. 2021;31:659-676 pubmed publisher
Pholcharee T, Oyen D, Flores Garcia Y, Gonzalez Paez G, Han Z, Williams K, et al. Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum. Nat Commun. 2021;12:1063 pubmed publisher
Travaglini K, Nabhan A, Penland L, Sinha R, Gillich A, Sit R, et al. A molecular cell atlas of the human lung from single-cell RNA sequencing. Nature. 2020;587:619-625 pubmed publisher
Turner J, Zhou J, Han J, Schmitz A, Rizk A, Alsoussi W, et al. Human germinal centres engage memory and naive B cells after influenza vaccination. Nature. 2020;586:127-132 pubmed publisher
Witkowski M, Dolgalev I, Evensen N, Ma C, Chambers T, Roberts K, et al. Extensive Remodeling of the Immune Microenvironment in B Cell Acute Lymphoblastic Leukemia. Cancer Cell. 2020;37:867-882.e12 pubmed publisher
. 2020 CIS Annual Meeting: Immune Deficiency & Dysregulation North American Conference. J Clin Immunol. 2020;40:1-163 pubmed publisher
Singh M, Jackson K, Wang J, Schofield P, Field M, Koppstein D, et al. Lymphoma Driver Mutations in the Pathogenic Evolution of an Iconic Human Autoantibody. Cell. 2020;180:878-894.e19 pubmed publisher
Rohner L, Reinhart R, Iype J, Bachmann S, Kaufmann T, Fux M. Impact of BH3-mimetics on Human and Mouse Blood Leukocytes: A Comparative Study. Sci Rep. 2020;10:222 pubmed publisher
Shih T, De S, Barnes B. RNAi Transfection Optimized in Primary Naïve B Cells for the Targeted Analysis of Human Plasma Cell Differentiation. Front Immunol. 2019;10:1652 pubmed publisher
Schoofs T, Barnes C, Suh Toma N, Golijanin J, Schommers P, Gruell H, et al. Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope. Immunity. 2019;50:1513-1529.e9 pubmed publisher
Usmani S, Murooka T, Deruaz M, Koh W, Sharaf R, Di Pilato M, et al. HIV-1 Balances the Fitness Costs and Benefits of Disrupting the Host Cell Actin Cytoskeleton Early after Mucosal Transmission. Cell Host Microbe. 2019;25:73-86.e5 pubmed publisher
Koppejan H, Jansen D, Hameetman M, Thomas R, Toes R, van Gaalen F. Altered composition and phenotype of mucosal-associated invariant T cells in early untreated rheumatoid arthritis. Arthritis Res Ther. 2019;21:3 pubmed publisher
Setliff I, McDonnell W, Raju N, Bombardi R, Murji A, Scheepers C, et al. Multi-Donor Longitudinal Antibody Repertoire Sequencing Reveals the Existence of Public Antibody Clonotypes in HIV-1 Infection. Cell Host Microbe. 2018;23:845-854.e6 pubmed publisher
Antonarakis E, Small E, Petrylak D, Quinn D, Kibel A, Chang N, et al. Antigen-Specific CD8 Lytic Phenotype Induced by Sipuleucel-T in Hormone-Sensitive or Castration-Resistant Prostate Cancer and Association with Overall Survival. Clin Cancer Res. 2018;24:4662-4671 pubmed publisher
SAJADI M, Dashti A, Rikhtegaran Tehrani Z, Tolbert W, Seaman M, Ouyang X, et al. Identification of Near-Pan-neutralizing Antibodies against HIV-1 by Deconvolution of Plasma Humoral Responses. Cell. 2018;173:1783-1795.e14 pubmed publisher
Verboven K, Wouters K, Gaens K, Hansen D, Bijnen M, Wetzels S, et al. Abdominal subcutaneous and visceral adipocyte size, lipolysis and inflammation relate to insulin resistance in male obese humans. Sci Rep. 2018;8:4677 pubmed publisher
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Baguma R, Penn Nicholson A, Smit E, Erasmus M, Day J, Makhethe L, et al. Application of a whole blood mycobacterial growth inhibition assay to study immunity against Mycobacterium tuberculosis in a high tuberculosis burden population. PLoS ONE. 2017;12:e0184563 pubmed publisher
Wouters K, Gaens K, Bijnen M, Verboven K, Jocken J, Wetzels S, et al. Circulating classical monocytes are associated with CD11c+ macrophages in human visceral adipose tissue. Sci Rep. 2017;7:42665 pubmed publisher
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Lu D, Tan Y, Kongpachith S, Cai X, Stein E, Lindstrom T, et al. Identifying functional anti-Staphylococcus aureus antibodies by sequencing antibody repertoires of patient plasmablasts. Clin Immunol. 2014;152:77-89 pubmed publisher
Tan Y, Blum L, Kongpachith S, Ju C, Cai X, Lindstrom T, et al. High-throughput sequencing of natively paired antibody chains provides evidence for original antigenic sin shaping the antibody response to influenza vaccination. Clin Immunol. 2014;151:55-65 pubmed publisher
Joseph A, Zheng J, Chen K, Dutta M, Chen C, Stiegler G, et al. Inhibition of in vivo HIV infection in humanized mice by gene therapy of human hematopoietic stem cells with a lentiviral vector encoding a broadly neutralizing anti-HIV antibody. J Virol. 2010;84:6645-53 pubmed publisher
Wang X, Hisha H, Mizokami T, Cui W, Cui Y, Shi A, et al. Mouse mesenchymal stem cells can support human hematopoiesis both in vitro and in vivo: the crucial role of neural cell adhesion molecule. Haematologica. 2010;95:884-91 pubmed publisher
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product information
Antigen :
CD19
Apps. Abbrev. :
FC, ICC, IHC-F
Cat # :
302234
Clone :
HIB19
Item :
Brilliant Violet 421™ anti-human CD19
Isotype :
Mouse IgG1, κ
Other Names :
B4
Size :
100 tests
Price (USD) :
381 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
BV421
Application Notes :
Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections^8 and blocking of B cell proliferation. Clone HIB19 is not recommended for formalin-fixed paraffin-embedded sections. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 302267 & 302268).; Clone HIB19 partially blocks anti-human CD19 clones 4G7 and SJ25C1 staining based on in-house testing;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA