product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PE anti-human CD19
catalog :
302208
quantity :
100 tests
price :
66 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
HIB19
reactivity :
human, mouse
application :
flow cytometry
more info or order :
citations: 96
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; fig 4a
Sullivan P, Kumar R, Li W, Hoglund V, Wang L, Zhang Y, et al. FGFR4-Targeted Chimeric Antigen Receptors Combined with Anti-Myeloid Polypharmacy Effectively Treat Orthotopic Rhabdomyosarcoma. Mol Cancer Ther. 2022;21:1608-1621 pubmed publisher
  • flow cytometry; human; 1:200; fig 3a
Turner J, Kim W, Kalaidina E, Goss C, Rauseo A, Schmitz A, et al. SARS-CoV-2 infection induces long-lived bone marrow plasma cells in humans. Nature. 2021;595:421-425 pubmed publisher
  • flow cytometry; mouse; 1:500; loading ...; fig s1b
Gang E, Kim H, Hsieh Y, Ruan Y, Ogana H, Lee S, et al. Integrin α6 mediates the drug resistance of acute lymphoblastic B-cell leukemia. Blood. 2020;136:210-223 pubmed publisher
  • flow cytometry; human; 1:200; loading ...; fig 2c
Zumaquero E, Stone S, Scharer C, Jenks S, Nellore A, Mousseau B, et al. IFNγ induces epigenetic programming of human T-bethi B cells and promotes TLR7/8 and IL-21 induced differentiation. elife. 2019;8: pubmed publisher
  • flow cytometry; human; loading ...; fig s1a
Lopes F, Bálint Å, Valvo S, Felce J, Hessel E, Dustin M, et al. Membrane nanoclusters of FcγRI segregate from inhibitory SIRPα upon activation of human macrophages. J Cell Biol. 2017;216:1123-1141 pubmed publisher
  • flow cytometry; human
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Graciliano N, Ten xf3 rio M, Fragoso M, Moura F, Botelho R, Tanabe E, et al. The impact on colostrum oxidative stress, cytokines, and immune cells composition after SARS-CoV-2 infection during pregnancy. Front Immunol. 2022;13:1031248 pubmed publisher
Ye Y, Chen Z, Jiang S, Jia F, Li T, Lu X, et al. Single-cell profiling reveals distinct adaptive immune hallmarks in MDA5+ dermatomyositis with therapeutic implications. Nat Commun. 2022;13:6458 pubmed publisher
Cao B, Liu M, Wang L, Zhu K, Cai M, Chen X, et al. Remodelling of tumour microenvironment by microwave ablation potentiates immunotherapy of AXL-specific CAR T cells against non-small cell lung cancer. Nat Commun. 2022;13:6203 pubmed publisher
SoRelle E, Reinoso Vizcaino N, Horn G, Luftig M. Epstein-Barr virus perpetuates B cell germinal center dynamics and generation of autoimmune-associated phenotypes in vitro. Front Immunol. 2022;13:1001145 pubmed publisher
Avsec D, x160 krlj Miklav x10d i x10d M, Burnik T, Kandu x161 er M, Bizjak M, Podgornik H, et al. Inhibition of p38 MAPK or immunoproteasome overcomes resistance of chronic lymphocytic leukemia cells to Bcl-2 antagonist venetoclax. Cell Death Dis. 2022;13:860 pubmed publisher
SoRelle E, Dai J, Reinoso Vizcaino N, Barry A, Chan C, Luftig M. Time-resolved transcriptomes reveal diverse B cell fate trajectories in the early response to Epstein-Barr virus infection. Cell Rep. 2022;40:111286 pubmed publisher
Polisetti N, Sharaf L, Reinhard T, Schlunck G. Isolation and ex vivo Expansion of Limbal Mesenchymal Stromal Cells. Bio Protoc. 2022;12: pubmed publisher
Sipe C, Kluesner M, Bingea S, Lahr W, Andrew A, Wang M, et al. Correction of Fanconi Anemia Mutations Using Digital Genome Engineering. Int J Mol Sci. 2022;23: pubmed publisher
Gu X, Zhang Y, Jiang W, Wang D, Lu J, Gu G, et al. Protective Human Anti-Poxvirus Monoclonal Antibodies Are Generated from Rare Memory B Cells Isolated by Multicolor Antigen Tetramers. Vaccines (Basel). 2022;10: pubmed publisher
Cai S, Fan C, Xie L, Zhong H, Li A, Lv S, et al. Single-cell RNA sequencing reveals the potential mechanism of heterogeneity of immunomodulatory properties of foreskin and umbilical cord mesenchymal stromal cells. Cell Biosci. 2022;12:115 pubmed publisher
Im N, Guillaumet Adkins A, Wal M, Rogers A, Frede J, Havig C, et al. Regulatory programs of B-cell activation and germinal center reaction allow B-ALL escape from CD19 CAR T-cell therapy. Cancer Immunol Res. 2022;: pubmed publisher
Sureshchandra S, Zulu M, Doratt B, Jankeel A, Tifrea D, Edwards R, et al. Single-cell RNA sequencing reveals immunological rewiring at the maternal-fetal interface following asymptomatic/mild SARS-CoV-2 infection. Cell Rep. 2022;39:110938 pubmed publisher
Mirchandani A, Jenkins S, Bain C, Sánchez García M, Lawson H, Coelho P, et al. Hypoxia shapes the immune landscape in lung injury and promotes the persistence of inflammation. Nat Immunol. 2022;23:927-939 pubmed publisher
Moquin Beaudry G, Benabdallah B, Maggiorani D, Le O, Li Y, Colas C, et al. Autologous humanized mouse models of iPSC-derived tumors enable characterization and modulation of cancer-immune cell interactions. Cell Rep Methods. 2022;2:100153 pubmed publisher
Kim S, Chu Y, Misoi M, Suarez Almazor M, Tayar J, Lu H, et al. Distinct molecular and immune hallmarks of inflammatory arthritis induced by immune checkpoint inhibitors for cancer therapy. Nat Commun. 2022;13:1970 pubmed publisher
Veatch J, Lee S, Shasha C, Singhi N, Szeto J, Moshiri A, et al. Neoantigen-specific CD4+ T cells in human melanoma have diverse differentiation states and correlate with CD8+ T cell, macrophage, and B cell function. Cancer Cell. 2022;40:393-409.e9 pubmed publisher
Schlicher L, Kulig P, von M xfc nchow A, Murphy M, Keller M. In Vitro Characterization of Sphingosine 1-Phosphate Receptor 1 (S1P1) Expression and Mediated Migration of Primary Human T and B Cells in the Context of Cenerimod, a Novel, Selective S1P1 Receptor Modulator. Int J Mol Sci. 2022;23: pubmed publisher
Kerdidani D, Aerakis E, Verrou K, Angelidis I, Douka K, Maniou M, et al. Lung tumor MHCII immunity depends on in situ antigen presentation by fibroblasts. J Exp Med. 2022;219: pubmed publisher
Mudd P, Minervina A, Pogorelyy M, Turner J, Kim W, Kalaidina E, et al. SARS-CoV-2 mRNA vaccination elicits a robust and persistent T follicular helper cell response in humans. Cell. 2022;185:603-613.e15 pubmed publisher
Ruan Y, Kim H, Ogana H, Gang E, Li S, Liu H, et al. In vitro and in vivo effects of AVA4746, a novel competitive antagonist of the ligand binding of VLA-4, in B-cell acute lymphoblastic leukemia. Exp Ther Med. 2022;23:47 pubmed publisher
Ando M, Kondo T, Tomisato W, Ito M, Shichino S, Srirat T, et al. Rejuvenating Effector/Exhausted CAR T Cells to Stem Cell Memory-Like CAR T Cells By Resting Them in the Presence of CXCL12 and the NOTCH Ligand. Cancer Res Commun. 2021;1:41-55 pubmed publisher
Fisher J, Walker C, Doyle A, Johnson P, Forconi F, Cragg M, et al. Selinexor Enhances NK Cell Activation Against Malignant B Cells via Downregulation of HLA-E. Front Oncol. 2021;11:785635 pubmed publisher
Yu H, Yang W, Huang J, Miao X, Wang B, Ren X, et al. GPR120 induces regulatory dendritic cells by inhibiting HK2-dependent glycolysis to alleviate fulminant hepatic failure. Cell Death Dis. 2021;13:1 pubmed publisher
Wang L, Xu D, Huang Q, Yang G, Zhang M, Bi J, et al. Characterization of Tonsil Microbiota and Their Effect on Adenovirus Reactivation in Tonsillectomy Samples. Microbiol Spectr. 2021;9:e0124621 pubmed publisher
Roider T, Brinkmann B, Kim V, Knoll M, Kolb C, Roessner P, et al. An autologous culture model of nodal B-cell lymphoma identifies ex vivo determinants of response to bispecific antibodies. Blood Adv. 2021;5:5060-5071 pubmed publisher
Jing Y, Luo L, Chen Y, Westerberg L, Zhou P, Xu Z, et al. SARS-CoV-2 infection causes immunodeficiency in recovered patients by downregulating CD19 expression in B cells via enhancing B-cell metabolism. Signal Transduct Target Ther. 2021;6:345 pubmed publisher
Wang X, Wu P, Li X, Zeng C, Zhu J, Zhou Y, et al. Extracellular Vesicles Inhibit Proliferation and Invasion of Ovarian Endometrial Stromal Cells and Their Expression of SF-1, ERβ, and Aromatase. Front Endocrinol (Lausanne). 2021;12:666195 pubmed publisher
Shen J, Xu Y, Zhang S, Lyu S, Huo Y, Zhu Y, et al. Single-cell transcriptome of early hematopoiesis guides arterial endothelial-enhanced functional T cell generation from human PSCs. Sci Adv. 2021;7:eabi9787 pubmed publisher
Merah Mourah F, Cohen S, Haziot A. A Two-Stage Flow Cytometry Strategy to Distinguish Single Cells from Doublets in Heterogeneous Cell Mixtures and Improve Cell Cluster Identification: Application to Human Monocyte Subpopulations. Curr Protoc. 2021;1:e229 pubmed publisher
Vereertbrugghen A, Colado A, Gargiulo E, Bezares R, Fernández Grecco H, Cordini G, et al. In Vitro Sensitivity to Venetoclax and Microenvironment Protection in Hairy Cell Leukemia. Front Oncol. 2021;11:598319 pubmed publisher
Zirbes A, Joseph J, Lopez J, Sayaman R, Basam M, Seewaldt V, et al. Changes in Immune Cell Types with Age in Breast are Consistent with a Decline in Immune Surveillance and Increased Immunosuppression. J Mammary Gland Biol Neoplasia. 2021;26:247-261 pubmed publisher
Kim S, Tayar J, Fu S, Ke D, Norry E, Sun A, et al. Newly developed pseudogout arthritis after therapy with MAGE-A4 directed TCR T cells responded to treatment with tocilizumab. J Immunother Cancer. 2021;9: pubmed publisher
Sureshchandra S, Marshall N, Mendoza N, Jankeel A, Zulu M, Messaoudi I. Functional and genomic adaptations of blood monocytes to pregravid obesity during pregnancy. iScience. 2021;24:102690 pubmed publisher
Amanat F, Thapa M, Lei T, Ahmed S, Adelsberg D, Carreño J, et al. SARS-CoV-2 mRNA vaccination induces functionally diverse antibodies to NTD, RBD, and S2. Cell. 2021;184:3936-3948.e10 pubmed publisher
Vora A, Mondala P, Costello C, MacLeod A, Crews L. Sensitive intranuclear flow cytometric quantification of IRF4 protein in multiple myeloma and normal human hematopoietic cells. STAR Protoc. 2021;2:100565 pubmed publisher
Caduff N, McHugh D, Rieble L, Forconi C, Ong echa J, Oluoch P, et al. KSHV infection drives poorly cytotoxic CD56-negative natural killer cell differentiation in vivo upon KSHV/EBV dual infection. Cell Rep. 2021;35:109056 pubmed publisher
Han A, Lee J, Lee M, Ko S, Shin H, Lee J, et al. Distinct Repopulation Activity in Hu-Mice Between CB- and LPB-CD34+ Cells by Enrichment of Transcription Factors. Int J Stem Cells. 2021;14:203-211 pubmed publisher
Richardson S, Ghazanfari R, Chhetri J, Enver T, Böiers C. In vitro differentiation of human pluripotent stem cells into the B lineage using OP9-MS5 co-culture. STAR Protoc. 2021;2:100420 pubmed publisher
Caeser R, Gao J, Di Re M, Gong C, Hodson D. Genetic manipulation and immortalized culture of ex vivo primary human germinal center B cells. Nat Protoc. 2021;16:2499-2519 pubmed publisher
Malik Chaudhry H, Prabhakar K, Ugamraj H, Boudreau A, Buelow B, Dang K, et al. TNB-486 induces potent tumor cell cytotoxicity coupled with low cytokine release in preclinical models of B-NHL. MAbs. 2021;13:1890411 pubmed publisher
Zhang Q, Xiang E, Rao W, Zhang Y, Xiao C, Li C, et al. Intra-articular injection of human umbilical cord mesenchymal stem cells ameliorates monosodium iodoacetate-induced osteoarthritis in rats by inhibiting cartilage degradation and inflammation. Bone Joint Res. 2021;10:226-236 pubmed publisher
de Jonge K, Tillé L, Lourenço J, Maby El Hajjami H, Nassiri S, Racle J, et al. Inflammatory B cells correlate with failure to checkpoint blockade in melanoma patients. Oncoimmunology. 2021;10:1873585 pubmed publisher
Khosravi Maharlooei M, Li H, Hoelzl M, Zhao G, Ruiz A, Misra A, et al. Role of the thymus in spontaneous development of a multi-organ autoimmune disease in human immune system mice. J Autoimmun. 2021;119:102612 pubmed publisher
Lu P, Wang S, Franzen C, Venkataraman G, McClure R, Li L, et al. Ibrutinib and venetoclax target distinct subpopulations of CLL cells: implication for residual disease eradication. Blood Cancer J. 2021;11:39 pubmed publisher
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Abdul Jawad S, Baù L, Alaguthurai T, Del Molino Del Barrio I, Laing A, Hayday T, et al. Acute Immune Signatures and Their Legacies in Severe Acute Respiratory Syndrome Coronavirus-2 Infected Cancer Patients. Cancer Cell. 2021;39:257-275.e6 pubmed publisher
Mondala P, Vora A, Zhou T, Lazzari E, Ladel L, Luo X, et al. Selective antisense oligonucleotide inhibition of human IRF4 prevents malignant myeloma regeneration via cell cycle disruption. Cell Stem Cell. 2021;28:623-636.e9 pubmed publisher
Wang J, Xu Y, Chen Z, Liang J, Lin Z, Liang H, et al. Liver Immune Profiling Reveals Pathogenesis and Therapeutics for Biliary Atresia. Cell. 2020;183:1867-1883.e26 pubmed publisher
Kreye J, Reincke S, Kornau H, Sánchez Sendin E, Corman V, Liu H, et al. A Therapeutic Non-self-reactive SARS-CoV-2 Antibody Protects from Lung Pathology in a COVID-19 Hamster Model. Cell. 2020;183:1058-1069.e19 pubmed publisher
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Kan S, Bito T, Shimabuku M, Taguchi J, Ohkusa T, Shimodaira S, et al. Impact of mature dendritic cells pulsed with a novel WT1 helper peptide on the induction of HLA‑A2‑restricted WT1‑reactive CD8+ T cells. Int J Oncol. 2020;57:1047-1056 pubmed publisher
Turner J, Zhou J, Han J, Schmitz A, Rizk A, Alsoussi W, et al. Human germinal centres engage memory and naive B cells after influenza vaccination. Nature. 2020;586:127-132 pubmed publisher
Kreye J, Reincke S, Kornau H, S xe1 nchez Sendin E, Max Corman V, Liu H, et al. A SARS-CoV-2 neutralizing antibody protects from lung pathology in a COVID-19 hamster model. bioRxiv. 2020;: pubmed publisher
Frame J, Kubaczka C, Long T, Esain V, Soto R, Hachimi M, et al. Metabolic Regulation of Inflammasome Activity Controls Embryonic Hematopoietic Stem and Progenitor Cell Production. Dev Cell. 2020;: pubmed publisher
Laing A, Lorenc A, Del Molino Del Barrio I, Das A, Fish M, Monin L, et al. A dynamic COVID-19 immune signature includes associations with poor prognosis. Nat Med. 2020;26:1623-1635 pubmed publisher
Li W, Qiu S, Chen J, Jiang S, Chen W, Jiang J, et al. Chimeric Antigen Receptor Designed to Prevent Ubiquitination and Downregulation Showed Durable Antitumor Efficacy. Immunity. 2020;53:456-470.e6 pubmed publisher
Lavaert M, Liang K, Vandamme N, Park J, Roels J, Kowalczyk M, et al. Integrated scRNA-Seq Identifies Human Postnatal Thymus Seeding Progenitors and Regulatory Dynamics of Differentiating Immature Thymocytes. Immunity. 2020;52:1088-1104.e6 pubmed publisher
Jackson Jones L, Smith P, Portman J, Magalhaes M, Mylonas K, Vermeren M, et al. Stromal Cells Covering Omental Fat-Associated Lymphoid Clusters Trigger Formation of Neutrophil Aggregates to Capture Peritoneal Contaminants. Immunity. 2020;52:700-715.e6 pubmed publisher
Zheng L, Ren L, Kouhi A, Khawli L, Hu P, Kaslow H, et al. A Humanized Lym-1 CAR with Novel DAP10/DAP12 Signaling Domains Demonstrates Reduced Tonic Signaling and Increased Antitumor Activity in B-Cell Lymphoma Models. Clin Cancer Res. 2020;26:3694-3706 pubmed publisher
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Chabi S, Uzan B, Naguibneva I, Rucci J, Fahy L, Calvo J, et al. Hypoxia Regulates Lymphoid Development of Human Hematopoietic Progenitors. Cell Rep. 2019;29:2307-2320.e6 pubmed publisher
Huang Y, Mouttet B, Warnatz H, Risch T, Rietmann F, Frommelt F, et al. The Leukemogenic TCF3-HLF Complex Rewires Enhancers Driving Cellular Identity and Self-Renewal Conferring EP300 Vulnerability. Cancer Cell. 2019;36:630-644.e9 pubmed publisher
Serra Peinado C, Grau Expósito J, Luque Ballesteros L, Astorga Gamaza A, Navarro J, Gallego Rodriguez J, et al. Expression of CD20 after viral reactivation renders HIV-reservoir cells susceptible to Rituximab. Nat Commun. 2019;10:3705 pubmed publisher
Cho A, Caldara A, Ran N, Menne Z, Kauffman R, Affer M, et al. Single-Cell Analysis Suggests that Ongoing Affinity Maturation Drives the Emergence of Pemphigus Vulgaris Autoimmune Disease. Cell Rep. 2019;28:909-922.e6 pubmed publisher
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Luong Gardiol N, Siddiqui I, Pizzitola I, Jeevan Raj B, Charmoy M, Huang Y, et al. γ-Catenin-Dependent Signals Maintain BCR-ABL1+ B Cell Acute Lymphoblastic Leukemia. Cancer Cell. 2019;35:649-663.e10 pubmed publisher
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product information
Antigen :
CD19
Apps. Abbrev. :
FC
Cat # :
302208
Clone :
HIB19
Item :
PE anti-human CD19
Isotype :
Mouse IgG1, κ
Other Names :
B4
Size :
100 tests
Price (USD) :
66 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PE
Application Notes :
Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections^8 and blocking of B cell proliferation. Clone HIB19 is not recommended for formalin-fixed paraffin-embedded sections. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 302267 & 302268).; Clone HIB19 partially blocks anti-human CD19 clones 4G7 and SJ25C1 staining based on in-house testing;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA