Brilliant Violet 570™ anti-human CD16 | BioLegend 302036 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Brilliant Violet 570™ anti-human CD16

catalog :

302036

quantity :

100 tests

price :

429 USD

clonality :

monoclonal

host :

mouse

conjugate :

Brilliant Violet 570

clone name :

3G8

reactivity :

human, rhesus macaque

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 10

Reference
Obradovic A, Chowdhury N, Haake S, Ager C, Wang V, Vlahos L, et al. Single-cell protein activity analysis identifies recurrence-associated renal tumor macrophages. Cell. 2021;184:2988-3005.e16 pubmed publisher
Mathewson N, Ashenberg O, Tirosh I, Gritsch S, Perez E, Marx S, et al. Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis. Cell. 2021;184:1281-1298.e26 pubmed publisher
Han Q, Bradley T, Williams W, Cain D, Montefiori D, Saunders K, et al. Neonatal Rhesus Macaques Have Distinct Immune Cell Transcriptional Profiles following HIV Envelope Immunization. Cell Rep. 2020;30:1553-1569.e6 pubmed publisher
Martin Gayo E, Gao C, Chen H, Ouyang Z, Kim D, Kolb K, et al. Immunological Fingerprints of Controllers Developing Neutralizing HIV-1 Antibodies. Cell Rep. 2020;30:984-996.e4 pubmed publisher
Meehan S, Kolyagin G, Parks D, Youngyunpipatkul J, Herzenberg L, Walther G, et al. Automated subset identification and characterization pipeline for multidimensional flow and mass cytometry data clustering and visualization. Commun Biol. 2019;2:229 pubmed publisher
Bradley T, Peppa D, Pedroza Pacheco I, Li D, Cain D, Henao R, et al. RAB11FIP5 Expression and Altered Natural Killer Cell Function Are Associated with Induction of HIV Broadly Neutralizing Antibody Responses. Cell. 2018;175:387-399.e17 pubmed publisher
Aliota M, Dudley D, Newman C, Mohr E, Gellerup D, Breitbach M, et al. Heterologous Protection against Asian Zika Virus Challenge in Rhesus Macaques. PLoS Negl Trop Dis. 2016;10:e0005168 pubmed publisher
Dudley D, Aliota M, Mohr E, Weiler A, Lehrer Brey G, Weisgrau K, et al. A rhesus macaque model of Asian-lineage Zika virus infection. Nat Commun. 2016;7:12204 pubmed publisher
Santra S, Tomaras G, Warrier R, Nicely N, Liao H, Pollara J, et al. Human Non-neutralizing HIV-1 Envelope Monoclonal Antibodies Limit the Number of Founder Viruses during SHIV Mucosal Infection in Rhesus Macaques. PLoS Pathog. 2015;11:e1005042 pubmed publisher
Stanisic D, Cutts J, Eriksson E, Fowkes F, Rosanas Urgell A, Siba P, et al. ?? T cells and CD14+ monocytes are predominant cellular sources of cytokines and chemokines associated with severe malaria. J Infect Dis. 2014;210:295-305 pubmed publisher

product information

Antigen :

CD16

Apps. Abbrev. :

Flow Cytometry

Cat # :

302036

Clone :

3G8

Item :

Brilliant Violet 570™ anti-human CD16

Isotype :

Mouse IgG1, κ

Other Names :

FcγRIII, Fc gamma receptor, Fc gamma receptor 3

Size :

100 tests

Price (USD) :

429 USD

Reactivity :

Human, Cynomolgus, Rhesus

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

BV570

Immunogen :

Human PMN cells

Application Notes :

The 3G8 antibody clone blocks neutrophil phagocytosis and stimulates NK cell proliferation. It has been reported that this clone interacts with the Fc RIIa and Fc RIIIb receptors causing neutrophil activation and aggregation 18 . Due to this phenomenon staining in whole blood may cause a reduction in the number of granulocytes or alter their scatter profile. Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections 6 , immunoprecipitation 3 , stimulation of NK cell proliferation 4 , blocking of phagocytosis 5 , and blocking of immunoglobulin binding to Fc RIII 7,8 . The Ultra-LEAF purified antibody (Endotoxin 0.01 EU/ug, Azide-Free, 0.2 um filtered) is recommended for functional assays (Cat. No. 302049, 302050, 302057, 302058).

more info or order :

BioLegend product webpage