product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
FITC anti-human CD14
catalog :
301803
quantity :
25 tests
price :
49 USD
clonality :
monoclonal
host :
mouse
conjugate :
FITC
clone name :
M5E2
reactivity :
human, rhesus macaque
application :
flow cytometry
more info or order :
citations: 75
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human
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Grivas A, Grigoriou M, Malissovas N, Sentis G, Filia A, Flouda S, et al. Combined - whole blood and skin fibroblasts- transcriptomic analysis in Psoriatic Arthritis reveals molecular signatures of activity, resistance and early response to treatment. Front Immunol. 2022;13:964274 pubmed publisher
Li F, Gao C, Li X, Wang J, Zhao Y, Ke Y, et al. Jiyuan oridonin A induces differentiation of acute myeloid leukemia cells including leukemic stem-like cells. Front Pharmacol. 2022;13:1001552 pubmed publisher
Qi F, Wang X, Zhao S, Wang C, Sun R, Wang H, et al. miR-let-7c-3p targeting on Egr-1 contributes to the committed differentiation of leukemia cells into monocyte/macrophages. Oncol Lett. 2022;24:273 pubmed publisher
Chen X, Gao C, Chu X, Zheng C, Luan Y, He X, et al. VEGF-Loaded Heparinised Gelatine-Hydroxyapatite-Tricalcium Phosphate Scaffold Accelerates Bone Regeneration via Enhancing Osteogenesis-Angiogenesis Coupling. Front Bioeng Biotechnol. 2022;10:915181 pubmed publisher
Zheng H, Chen Y, Li J, Li H, Zhao X, Li J, et al. Longitudinal analyses reveal distinct immune response landscapes in lung and intestinal tissues from SARS-CoV-2-infected rhesus macaques. Cell Rep. 2022;39:110864 pubmed publisher
Yao J, Li G, Cui Z, Chen P, Wang J, Hu Z, et al. The Histone Deacetylase Inhibitor I1 Induces Differentiation of Acute Leukemia Cells With MLL Gene Rearrangements via Epigenetic Modification. Front Pharmacol. 2022;13:876076 pubmed publisher
Ma X, Zhao M, Wu Z, Yao J, Zhang L, Wang J, et al. The Histone Deacetylase Inhibitor I13 Induces Differentiation of M2, M3 and M5 Subtypes of Acute Myeloid Leukemia Cells and Leukemic Stem-Like Cells. Front Oncol. 2022;12:855570 pubmed publisher
Meng Q, Duan X, Yang Q, Xue D, Liu Z, Li Y, et al. SLAMF6/Ly108 promotes the development of hepatocellular carcinoma via facilitating macrophage M2 polarization. Oncol Lett. 2022;23:83 pubmed publisher
Aarsund M, Segers F, Wu Y, Inngjerdingen M. Comparison of characteristics and tumor targeting properties of extracellular vesicles derived from primary NK cells or NK-cell lines stimulated with IL-15 or IL-12/15/18. Cancer Immunol Immunother. 2022;71:2227-2238 pubmed publisher
Wu Q, Huang Q, Jiang Y, Sun F, Liang B, Wang J, et al. Remodeling Chondroitin-6-Sulfate-Mediated Immune Exclusion Enhances Anti-PD-1 Response in Colorectal Cancer with Microsatellite Stability. Cancer Immunol Res. 2022;10:182-199 pubmed publisher
Ceglia V, Zurawski S, Montes M, Kroll M, Bouteau A, Wang Z, et al. Anti-CD40 Antibody Fused to CD40 Ligand Is a Superagonist Platform for Adjuvant Intrinsic DC-Targeting Vaccines. Front Immunol. 2021;12:786144 pubmed publisher
Saha R, Pradhan S, Shalimar -, Das P, Mishra P, Singh R, et al. Inflammatory signature in acute-on-chronic liver failure includes increased expression of granulocyte genes ELANE, MPO and CD177. Sci Rep. 2021;11:18849 pubmed publisher
Ceglia V, Zurawski S, Montes M, Bouteau A, Wang Z, Ellis J, et al. Anti-CD40 Antibodies Fused to CD40 Ligand Have Superagonist Properties. J Immunol. 2021;207:2060-2076 pubmed publisher
Mitsune A, Yamada M, Fujino N, Numakura T, Ichikawa T, Suzuki A, et al. Upregulation of leukocyte immunoglobulin-like receptor B4 on interstitial macrophages in COPD; their possible protective role against emphysema formation. Respir Res. 2021;22:232 pubmed publisher
Ziegler C, Miao V, Owings A, Navia A, Tang Y, Bromley J, et al. Impaired local intrinsic immunity to SARS-CoV-2 infection in severe COVID-19. Cell. 2021;184:4713-4733.e22 pubmed publisher
Wang M, Yan Y, Zhang Z, Yao X, Duan X, Jiang Z, et al. Programmed PPAR-α downregulation induces inflammaging by suppressing fatty acid catabolism in monocytes. iScience. 2021;24:102766 pubmed publisher
Cheng Y, Gunasegaran B, Singh H, Dutertre C, Loh C, Lim J, et al. Non-terminally exhausted tumor-resident memory HBV-specific T cell responses correlate with relapse-free survival in hepatocellular carcinoma. Immunity. 2021;54:1825-1840.e7 pubmed publisher
Zhao Y, Lv J, Zhang H, Xie J, Dai H, Zhang X. Gene Expression Profiles Analyzed Using Integrating RNA Sequencing, and Microarray Reveals Increased Inflammatory Response, Proliferation, and Osteoclastogenesis in Pigmented Villonodular Synovitis. Front Immunol. 2021;12:665442 pubmed publisher
Liu C, Gong Y, Zhang H, Yang H, Zeng Y, Bian Z, et al. Delineating spatiotemporal and hierarchical development of human fetal innate lymphoid cells. Cell Res. 2021;: pubmed publisher
Reyes M, Filbin M, Bhattacharyya R, Sonny A, Mehta A, Billman K, et al. Plasma from patients with bacterial sepsis or severe COVID-19 induces suppressive myeloid cell production from hematopoietic progenitors in vitro. Sci Transl Med. 2021;13: pubmed publisher
Ren X, Xiao J, Zhang W, Wang F, Yan Y, Wu X, et al. Inhibition of CCL7 derived from Mo-MDSCs prevents metastatic progression from latency in colorectal cancer. Cell Death Dis. 2021;12:484 pubmed publisher
Hiatt J, Cavero D, McGregor M, Zheng W, Budzik J, Roth T, et al. Efficient generation of isogenic primary human myeloid cells using CRISPR-Cas9 ribonucleoproteins. Cell Rep. 2021;35:109105 pubmed publisher
Langnau C, Rohlfing A, Gekeler S, G xfc nter M, P xf6 schel S, Petersen Uribe x, et al. Platelet Activation and Plasma Levels of Furin Are Associated With Prognosis of Patients With Coronary Artery Disease and COVID-19. Arterioscler Thromb Vasc Biol. 2021;41:2080-2096 pubmed publisher
Qu M, Duan Y, Zhao M, Wang Z, Zhao M, Zhao Y, et al. Jiyuan Oridonin A Overcomes Differentiation Blockade in Acute Myeloid Leukemia Cells With MLL Rearrangements via Multiple Signaling Pathways. Front Oncol. 2021;11:659720 pubmed publisher
Zhao M, Wang J, Qu M, Zhao Y, Wang H, Ke Y, et al. OGP46 Induces Differentiation of Acute Myeloid Leukemia Cells via Different Optimal Signaling Pathways. Front Cell Dev Biol. 2021;9:652972 pubmed publisher
Liao H, Han M, Cheng W, Zhang C, Li H, Li M, et al. Decidual-derived RANKL facilitates macrophages accumulation and residence at the maternal-fetal interface in human early pregnancy. Am J Reprod Immunol. 2021;86:e13406 pubmed publisher
Sutton H, Aye R, Idris A, Vistein R, Nduati E, Kai O, et al. Atypical B cells are part of an alternative lineage of B cells that participates in responses to vaccination and infection in humans. Cell Rep. 2021;34:108684 pubmed publisher
Zhang S, Zhang R, Qiao P, Ma X, Lu R, Wang F, et al. Metformin-Induced MicroRNA-34a-3p Downregulation Alleviates Senescence in Human Dental Pulp Stem Cells by Targeting CAB39 through the AMPK/mTOR Signaling Pathway. Stem Cells Int. 2021;2021:6616240 pubmed publisher
Wang S, Shen Y, Li J, Liu Y, Cheng L, Wu S, et al. Entecavir-induced interferon-λ1 suppresses type 2 innate lymphoid cells in patients with hepatitis B virus-related liver cirrhosis. J Viral Hepat. 2021;28:795-808 pubmed publisher
Wang H, He J, Xu C, Chen X, Yang H, Shi S, et al. Decoding Human Megakaryocyte Development. Cell Stem Cell. 2021;28:535-549.e8 pubmed publisher
Poran A, Scherer J, Bushway M, Besada R, Balogh K, Wanamaker A, et al. Combined TCR Repertoire Profiles and Blood Cell Phenotypes Predict Melanoma Patient Response to Personalized Neoantigen Therapy plus Anti-PD-1. Cell Rep Med. 2020;1:100141 pubmed publisher
Jackson R, Lukacs J, Zehbe I. The Potentials and Pitfalls of a Human Cervical Organoid Model Including Langerhans Cells. Viruses. 2020;12: pubmed publisher
Zavareh R, Spangenberg S, Woods A, Martínez Peña F, Lairson L. HSP90 Inhibition Enhances Cancer Immunotherapy by Modulating the Surface Expression of Multiple Immune Checkpoint Proteins. Cell Chem Biol. 2021;28:158-168.e5 pubmed publisher
Wang Z, Zheng G, Li G, Wang M, Ma Z, Li H, et al. Methylprednisolone alleviates multiple sclerosis by expanding myeloid-derived suppressor cells via glucocorticoid receptor β and S100A8/9 up-regulation. J Cell Mol Med. 2020;24:13703-13714 pubmed publisher
Wells D, van Buuren M, Dang K, Hubbard Lucey V, Sheehan K, Campbell K, et al. Key Parameters of Tumor Epitope Immunogenicity Revealed Through a Consortium Approach Improve Neoantigen Prediction. Cell. 2020;183:818-834.e13 pubmed publisher
Fekete T, xc1 gics B, Bencze D, Bene K, Sz xe1 nt xf3 A, Tarr T, et al. Regulation of RLR-Mediated Antiviral Responses of Human Dendritic Cells by mTOR. Front Immunol. 2020;11:572960 pubmed publisher
Hu X, Liu Y, Zhang X, Kong D, Kong J, Zhao D, et al. The anti-B7-H4 checkpoint synergizes trastuzumab treatment to promote phagocytosis and eradicate breast cancer. Neoplasia. 2020;22:539-553 pubmed publisher
Pierini S, Tanyi J, Simpkins F, George E, Uribe Herranz M, Drapkin R, et al. Ovarian granulosa cell tumor characterization identifies FOXL2 as an immunotherapeutic target. JCI Insight. 2020;5: pubmed publisher
Dinh H, Eggert T, Meyer M, Zhu Y, Olingy C, Llewellyn R, et al. Coexpression of CD71 and CD117 Identifies an Early Unipotent Neutrophil Progenitor Population in Human Bone Marrow. Immunity. 2020;53:319-334.e6 pubmed publisher
Oguri Y, Shinoda K, Kim H, Alba D, Bolus W, Wang Q, et al. CD81 Controls Beige Fat Progenitor Cell Growth and Energy Balance via FAK Signaling. Cell. 2020;: pubmed publisher
Le J, Park J, Ha V, Luong A, Branciamore S, Rodin A, et al. Single-Cell RNA-Seq Mapping of Human Thymopoiesis Reveals Lineage Specification Trajectories and a Commitment Spectrum in T Cell Development. Immunity. 2020;52:1105-1118.e9 pubmed publisher
Zhang D, Jiang F, Zaynagetdinov R, Huang H, Sood V, Wang H, et al. Identification and characterization of M6903, an antagonistic anti-TIM-3 monoclonal antibody. Oncoimmunology. 2020;9:1744921 pubmed publisher
Jankeel A, Menicucci A, Woolsey C, Fenton K, Mendoza N, Versteeg K, et al. Early Transcriptional Changes within Liver, Adrenal Gland, and Lymphoid Tissues Significantly Contribute to Ebola Virus Pathogenesis in Cynomolgus Macaques. J Virol. 2020;94: pubmed publisher
Wang D, Liu N, Xie Y, Song B, Kong S, Sun X. Different culture method changing CD105 expression in amniotic fluid MSCs without affecting differentiation ability or immune function. J Cell Mol Med. 2020;24:4212-4222 pubmed publisher
Woolsey C, Jankeel A, Matassov D, Geisbert J, Agans K, Borisevich V, et al. Immune correlates of postexposure vaccine protection against Marburg virus. Sci Rep. 2020;10:3071 pubmed publisher
Forbester J, Clement M, Wellington D, Yeung A, Dimonte S, Marsden M, et al. IRF5 Promotes Influenza Virus-Induced Inflammatory Responses in Human Induced Pluripotent Stem Cell-Derived Myeloid Cells and Murine Models. J Virol. 2020;94: pubmed publisher
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Lin F, Yin H, Li X, Zhu G, He W, Gou X. Bladder cancer cell‑secreted exosomal miR‑21 activates the PI3K/AKT pathway in macrophages to promote cancer progression. Int J Oncol. 2020;56:151-164 pubmed publisher
Zhao Y, Lee C, Lin C, Gassen R, Xu X, Huang Z, et al. PD-L1:CD80 Cis-Heterodimer Triggers the Co-stimulatory Receptor CD28 While Repressing the Inhibitory PD-1 and CTLA-4 Pathways. Immunity. 2019;51:1059-1073.e9 pubmed publisher
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Rao Z, Pace S, Jordan P, Bilancia R, Troisi F, Börner F, et al. Vacuolar (H+)-ATPase Critically Regulates Specialized Proresolving Mediator Pathways in Human M2-like Monocyte-Derived Macrophages and Has a Crucial Role in Resolution of Inflammation. J Immunol. 2019;203:1031-1043 pubmed publisher
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Yang X, Chen Y, Li J, Chen L, Ren H, Liu Y, et al. Hypertonic saline maintains coagulofibrinolytic homeostasis following moderate‑to‑severe traumatic brain injury by regulating monocyte phenotype via expression of lncRNAs. Mol Med Rep. 2019;19:1083-1091 pubmed publisher
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Autenrieth S, Grimm S, Rittig S, Grunebach F, Gouttefangeas C, Buhring H. Profiling of primary peripheral blood- and monocyte-derived dendritic cells using monoclonal antibodies from the HLDA10 Workshop in Wollongong, Australia. Clin Transl Immunology. 2015;4:e50 pubmed publisher
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product information
Antigen :
CD14
Apps. Abbrev. :
FC
Cat # :
301803
Clone :
M5E2
Item :
FITC anti-human CD14
Isotype :
Mouse IgG2a, κ
Other Names :
LPS receptor
Size :
25 tests
Price (USD) :
49 USD
Reactivity :
Human, Cynomolgus, Rhesus
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
FITC
Immunogen :
Full-length human CD14 protein
Application Notes :
The M5E2 antibody inhibits monocyte activation and cytokine production induced by LPS. Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen sections, blocking of LPS stimulation^4, and immunofluorescence microscopy^5. Clone M5E2 is not recommended for immunohistochemical staining of formalin-fixed paraffin-embedded sections. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 301861 and 301862).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA