Babco, Signet, Sternberger Monoclonals, Senetek, Covance

antibody

Ultra-LEAF™ Purified anti-human CD11c

301631

100 μg

237 USD

monoclonal

mouse

nonconjugated

3.9

immunohistochemistry, neutralization, flow cytometry

FC, CyTOF®, Block, IHC

301631

3.9

Ultra-LEAF™ Purified anti-human CD11c

Mouse IgG1, κ

Integrin αX subunit, CR4, p150, ITGAX

100 μg

237 USD

Human, Cynomolgus, Rhesus

Monoclonal

Mouse

ULEAF

Clone 3.9 preferentially binds the activated form of CD11c, is specific for the I domain of CD11c, and is able to partially block the binding of CD11c and ICAM-4. 3.9 binding is divalent cation dependent^12. While analyzing blood, it is best to use heparin as the anti-coagulant and not EDTA. Since the ability of clone 3.9 to bind to its target is divalent cation dependent, the usage of EDTA as an anti-coagulant may be detrimental to staining due to its chelating properties.Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections^4, and functional assays^5,6. The LEAF™ purified antibody (Endotoxin <0.1 EU/μg, Azide-Free, 0.2 μm filtered) is recommended for functional assays (Cat. No. 301616). For highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 301632) with a lower endotoxin limit than standard LEAF™ purified antibodies (Endotoxin <0.01 EU/µg).;