Ultra-LEAF™ Purified anti-human CD11c | BioLegend 301631 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Ultra-LEAF™ Purified anti-human CD11c

catalog :

301631

quantity :

100 μg

price :

237 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3.9

The same clone is also sold as:

Invitrogen: 15-0116-42, 46-0116-41, MA1-46052, 11-0116-42, 56-0116-41, 47-0116-41, 13-0116-82, 367-0116-42, 61-0116-42, 56-0116-42, 14-0116-82, 25-0116-42, 78-0116-42, 64-0116-42, 17-0116-42, 35-0116-42, 69-0116-42, 11-0116-41, 14-0116-95, 368-0116-42, 63-0116-42, 46-0116-42, 367-0116-41, 12-0116-42, 14-0116-37, 48-0116-41, 47-0116-42, 61-0116-41, 368-0116-41, 67-0116-42, 12-0116-41, 14-0116-80, 58-0116-41, 48-0116-42
Rockland Immunochemicals: 200-326-N63, 200-308-N63, 200-302-N63
Abcam: ab11029
Abnova: MAB12219, MAB6036, MAB6037, MAB5620
ichorbio: ICH1008
Boster: FC00357-PE, FC00357
Novus Biologicals: NB100-2711
Santa Cruz Biotechnology: sc-1185

reactivity :

human, chimpanzee

application :

immunohistochemistry, neutralization, flow cytometry

citations: 4

Reference
Arensman M, Yang X, Zhong W, Bisulco S, Upeslacis E, Rosfjord E, et al. Anti-tumor immunity influences cancer cell reliance upon ATG7. Oncoimmunology. 2020;9:1800162 pubmed publisher
Fox A, Dutt T, Karger B, Obregón Henao A, Anderson G, Henao Tamayo M. Acquisition of High-Quality Spectral Flow Cytometry Data. Curr Protoc Cytom. 2020;93:e74 pubmed publisher
Xie Y, Peng J, Pang J, Guo K, Zhang L, Yin S, et al. Biglycan regulates neuroinflammation by promoting M1 microglial activation in early brain injury after experimental subarachnoid hemorrhage. J Neurochem. 2020;152:368-380 pubmed publisher
Dong M, Wang G, Chow R, Ye L, Zhu L, Dai X, et al. Systematic Immunotherapy Target Discovery Using Genome-Scale In Vivo CRISPR Screens in CD8 T Cells. Cell. 2019;178:1189-1204.e23 pubmed publisher

product information

Antigen :

CD11c

Apps. Abbrev. :

Flow Cytometry, CyTOF®, Block, IHC

Cat # :

301631

Clone :

3.9

Item :

Ultra-LEAF™ Purified anti-human CD11c

Isotype :

Mouse IgG1, κ

Other Names :

Integrin αX subunit, CR4, p150, ITGAX

Size :

100 μg

Price (USD) :

237 USD

Reactivity :

Human, African Green, Baboon, Chimpanzee, Cynomolgus, Rhesus, Squirrel Monkey

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

ULEAF

Application Notes :

Clone 3.9 preferentially binds the activated form of CD11c, is specific for the I domain of CD11c, and is able to partially block the binding of CD11c and ICAM-4. 3.9 binding is divalent cation dependent 12 . While analyzing blood, it is best to use heparin as the anti-coagulant and not EDTA. Since the ability of clone 3.9 to bind to its target is divalent cation dependent, the usage of EDTA as an anti-coagulant may be detrimental to staining due to its chelating properties. Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections 4 , and functional assays 5,6 . The LEAF™ purified antibody (Endotoxin 0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 301616). For highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 301632) with a lower endotoxin limit than standard LEAF™ purified antibodies (Endotoxin 0.01 EU/µg).