product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PerCP/Cyanine5.5 anti-human CD11c
catalog :
301624
quantity :
100 tests
price :
358 USD
clonality :
monoclonal
host :
mouse
conjugate :
PerCP/Cy5.5
clone name :
3.9
reactivity :
human, chimpanzee
application :
flow cytometry
more info or order :
citations: 14
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human
Bendall S, Simonds E, Qiu P, Amir E, Krutzik P, Finck R, et al. Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. Science. 2011;332:687-96 pubmed publisher
Afolabi L, Bi J, Li X, Adeshakin A, Adeshakin F, Wu H, et al. Synergistic Tumor Cytolysis by NK Cells in Combination With a Pan-HDAC Inhibitor, Panobinostat. Front Immunol. 2021;12:701671 pubmed publisher
Keck S, Galati Fournier V, Kym U, Moesch M, Usemann J, Muller I, et al. Lack of Mucosal Cholinergic Innervation Is Associated With Increased Risk of Enterocolitis in Hirschsprung's Disease. Cell Mol Gastroenterol Hepatol. 2021;12:507-545 pubmed publisher
Wu J, Weisshaar N, Hotz Wagenblatt A, Madi A, Ma S, Mieg A, et al. Skeletal muscle antagonizes antiviral CD8+ T cell exhaustion. Sci Adv. 2020;6:eaba3458 pubmed publisher
Eken A, Okus Z, Erdem S, Azizoglu Z, Haliloglu Y, Bicer A, et al. IL-15 negatively regulates curdlan-induced IL-23 production by human monocyte-derived dendritic cells and subsequent Th17 response. North Clin Istanb. 2019;6:379-387 pubmed publisher
Hartmann W, Brunn M, Stetter N, Gagliani N, Muscate F, Stanelle Bertram S, et al. Helminth Infections Suppress the Efficacy of Vaccination against Seasonal Influenza. Cell Rep. 2019;29:2243-2256.e4 pubmed publisher
Blaszczak A, Jalilvand A, Liu J, Wright V, Suzo A, Needleman B, et al. Human Visceral Adipose Tissue Macrophages Are Not Adequately Defined by Standard Methods of Characterization. J Diabetes Res. 2019;2019:8124563 pubmed publisher
Perry J, Russler Germain E, Zhou Y, Purtha W, Cooper M, Choi J, et al. Transfer of Cell-Surface Antigens by Scavenger Receptor CD36 Promotes Thymic Regulatory T Cell Receptor Repertoire Development and Allo-tolerance. Immunity. 2018;48:923-936.e4 pubmed publisher
Auat M, Cardoso C, Santos Pirath I, Rudolf Oliveira R, Matiollo C, Lange B, et al. Evaluation of CD307a expression patterns during normal B-cell maturation and in B-cell malignancies by flow cytometry. Cytometry B Clin Cytom. 2018;94:588-595 pubmed publisher
Dimitrov V, Bouttier M, Boukhaled G, Salehi Tabar R, Avramescu R, Memari B, et al. Hormonal vitamin D up-regulates tissue-specific PD-L1 and PD-L2 surface glycoprotein expression in humans but not mice. J Biol Chem. 2017;292:20657-20668 pubmed publisher
Surdziel E, Clay I, Nigsch F, Thiemeyer A, Allard C, Hoffman G, et al. Multidimensional pooled shRNA screens in human THP-1 cells identify candidate modulators of macrophage polarization. PLoS ONE. 2017;12:e0183679 pubmed publisher
Asai A, Okajima F, Nakagawa K, Ibusuki D, Tanimura K, Nakajima Y, et al. Phosphatidylcholine hydroperoxide-induced THP-1 cell adhesion to intracellular adhesion molecule-1. J Lipid Res. 2009;50:957-65 pubmed publisher
Gurer C, Strowig T, Brilot F, Pack M, Trumpfheller C, Arrey F, et al. Targeting the nuclear antigen 1 of Epstein-Barr virus to the human endocytic receptor DEC-205 stimulates protective T-cell responses. Blood. 2008;112:1231-9 pubmed publisher
Sadhu C, Ting H, Lipsky B, Hensley K, Garcia Martinez L, Simon S, et al. CD11c/CD18: novel ligands and a role in delayed-type hypersensitivity. J Leukoc Biol. 2007;81:1395-403 pubmed
product information
Antigen :
CD11c
Apps. Abbrev. :
Flow Cytometry
Cat # :
301624
Clone :
3.9
Item :
PerCP/Cyanine5.5 anti-human CD11c
Isotype :
Mouse IgG1, κ
Other Names :
Integrin αX subunit, CR4, p150, ITGAX
Size :
100 tests
Price (USD) :
358 USD
Reactivity :
Human, African Green, Baboon, Chimpanzee, Cynomolgus, Rhesus, Squirrel Monkey
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PERCP_CYANINE5.5
Application Notes :
Clone 3.9 preferentially binds the activated form of CD11c, is specific for the I domain of CD11c, and is able to partially block the binding of CD11c and ICAM-4. 3.9 binding is divalent cation dependent 12 . While analyzing blood, it is best to use heparin as the anti-coagulant and not EDTA. Since the ability of clone 3.9 to bind to its target is divalent cation dependent, the usage of EDTA as an anti-coagulant may be detrimental to staining due to its chelating properties. Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections 4 , and functional assays 5,6 . The LEAF purified antibody (Endotoxin 0.1 EU/ug, Azide-Free, 0.2 um filtered) is recommended for functional assays (Cat. No. 301616). For highly sensitive assays, we recommend Ultra-LEAF purified antibody (Cat. No. 301632) with a lower endotoxin limit than standard LEAF purified antibodies (Endotoxin 0.01 EU/ug).
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA