Alexa Fluor® 488 anti-human CD11c | BioLegend 301617 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Alexa Fluor® 488 anti-human CD11c

catalog :

301617

quantity :

25 tests

price :

112 USD

clonality :

monoclonal

host :

mouse

conjugate :

AF488

clone name :

3.9

reactivity :

human

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 13

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human	Hautefort A, Girerd B, Montani D, Cohen Kaminsky S, Price L, Lambrecht B, et al. T-helper 17 cell polarization in pulmonary arterial hypertension. Chest. 2015;147:1610-1620 pubmed publisher
flow cytometry; human	Bendall S, Simonds E, Qiu P, Amir E, Krutzik P, Finck R, et al. Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. Science. 2011;332:687-96 pubmed publisher
	Anderson A, Wu I, Parrillo A, Wolf M, Maestas D, Graham I, et al. An immunologically active, adipose-derived extracellular matrix biomaterial for soft tissue reconstruction: concept to clinical trial. NPJ Regen Med. 2022;7:6 pubmed publisher
	Molina M, Hoffman E, Stokes J, Kummet N, Smith K, Baker F, et al. Regulatory Dendritic Cells Induced by Bendamustine Are Associated With Enhanced Flt3 Expression and Alloreactive T-Cell Death. Front Immunol. 2021;12:699128 pubmed publisher
	Singh A, Kazer S, Roider J, Krista K, Millar J, Asowata O, et al. Innate Lymphoid Cell Activation and Sustained Depletion in Blood and Tissue of Children Infected with HIV from Birth Despite Antiretroviral Therapy. Cell Rep. 2020;32:108153 pubmed publisher
	Gomes A, Kurochkin I, Chang B, DANIEL M, Law K, Satija N, et al. Cooperative Transcription Factor Induction Mediates Hemogenic Reprogramming. Cell Rep. 2018;25:2821-2835.e7 pubmed publisher
	Bradley T, Peppa D, Pedroza Pacheco I, Li D, Cain D, Henao R, et al. RAB11FIP5 Expression and Altered Natural Killer Cell Function Are Associated with Induction of HIV Broadly Neutralizing Antibody Responses. Cell. 2018;175:387-399.e17 pubmed publisher
	Macal M, Tam M, Hesser C, Di Domizio J, Léger P, Gilliet M, et al. CD28 Deficiency Enhances Type I IFN Production by Murine Plasmacytoid Dendritic Cells. J Immunol. 2016;196:1900-9 pubmed publisher
	Wang L, Liu J, Zhang A, Cheng P, Zhang X, Lv S, et al. BVT.2733, a selective 11?-hydroxysteroid dehydrogenase type 1 inhibitor, attenuates obesity and inflammation in diet-induced obese mice. PLoS ONE. 2012;7:e40056 pubmed publisher
	Beitnes A, Raki M, Brottveit M, Lundin K, Jahnsen F, Sollid L. Rapid accumulation of CD14+CD11c+ dendritic cells in gut mucosa of celiac disease after in vivo gluten challenge. PLoS ONE. 2012;7:e33556 pubmed publisher
	Asai A, Okajima F, Nakagawa K, Ibusuki D, Tanimura K, Nakajima Y, et al. Phosphatidylcholine hydroperoxide-induced THP-1 cell adhesion to intracellular adhesion molecule-1. J Lipid Res. 2009;50:957-65 pubmed publisher
	Gurer C, Strowig T, Brilot F, Pack M, Trumpfheller C, Arrey F, et al. Targeting the nuclear antigen 1 of Epstein-Barr virus to the human endocytic receptor DEC-205 stimulates protective T-cell responses. Blood. 2008;112:1231-9 pubmed publisher
	Sadhu C, Ting H, Lipsky B, Hensley K, Garcia Martinez L, Simon S, et al. CD11c/CD18: novel ligands and a role in delayed-type hypersensitivity. J Leukoc Biol. 2007;81:1395-403 pubmed

product information

Antigen :

CD11c

Apps. Abbrev. :

Flow Cytometry

Cat # :

301617

Clone :

3.9

Item :

Alexa Fluor® 488 anti-human CD11c

Isotype :

Mouse IgG1, κ

Other Names :

Integrin αX subunit, CR4, p150, ITGAX

Size :

25 tests

Price (USD) :

112 USD

Reactivity :

Human, Cynomolgus, Rhesus

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

A488

Application Notes :

Clone 3.9 preferentially binds the activated form of CD11c, is specific for the I domain of CD11c, and is able to partially block the binding of CD11c and ICAM-4. 3.9 binding is divalent cation dependent 12 . While analyzing blood, it is best to use heparin as the anti-coagulant and not EDTA. Since the ability of clone 3.9 to bind to its target is divalent cation dependent, the usage of EDTA as an anti-coagulant may be detrimental to staining due to its chelating properties. Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections 4 , and functional assays 5,6 . The LEAF purified antibody (Endotoxin 0.1 EU/ug, Azide-Free, 0.2 um filtered) is recommended for functional assays (Cat. No. 301616). For highly sensitive assays, we recommend Ultra-LEAF purified antibody (Cat. No. 301632) with a lower endotoxin limit than standard LEAF purified antibodies (Endotoxin 0.01 EU/ug).

more info or order :

BioLegend product webpage