PE anti-human CD11c | BioLegend 301605 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

PE anti-human CD11c

catalog :

301605

quantity :

25 tests

price :

83 USD

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

3.9

reactivity :

human

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human	Koido S, Homma S, Okamoto M, Takakura K, Mori M, Yoshizaki S, et al. Treatment with chemotherapy and dendritic cells pulsed with multiple Wilms' tumor 1 (WT1)-specific MHC class I/II-restricted epitopes for pancreatic cancer. Clin Cancer Res. 2014;20:4228-39 pubmed publisher
flow cytometry; human	Bendall S, Simonds E, Qiu P, Amir E, Krutzik P, Finck R, et al. Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. Science. 2011;332:687-96 pubmed publisher
	Oliveira J, Gandini M, Sales J, Fujimori S, Barbosa M, Frutuoso V, et al. Mycobacterium leprae induces a tolerogenic profile in monocyte-derived dendritic cells via TLR2 induction of IDO. J Leukoc Biol. 2021;110:167-176 pubmed publisher
	Kan S, Bito T, Shimabuku M, Taguchi J, Ohkusa T, Shimodaira S, et al. Impact of mature dendritic cells pulsed with a novel WT1 helper peptide on the induction of HLA‑A2‑restricted WT1‑reactive CD8+ T cells. Int J Oncol. 2020;57:1047-1056 pubmed publisher
	Eccles J, Turner R, Kirk N, Muehling L, Borish L, Steinke J, et al. T-bet+ Memory B Cells Link to Local Cross-Reactive IgG upon Human Rhinovirus Infection. Cell Rep. 2020;30:351-366.e7 pubmed publisher
	Matsuyama H, Isshiki T, Chiba A, Yamaguchi T, Murayama G, Akasaka Y, et al. Activation of mucosal-associated invariant T cells in the lungs of sarcoidosis patients. Sci Rep. 2019;9:13181 pubmed publisher
	Li G, Zhang Z, Reszka Blanco N, Li F, Chi L, Ma J, et al. Specific Activation In Vivo of HIV-1 by a Bromodomain Inhibitor from Monocytic Cells in Humanized Mice under Antiretroviral Therapy. J Virol. 2019;93: pubmed publisher
	Bravo Flores E, Mancilla Herrera I, Espino y Sosa S, Ortiz Ramirez M, Flores Rueda V, Ibargüengoitia Ochoa F, et al. Macrophage Populations in Visceral Adipose Tissue from Pregnant Women: Potential Role of Obesity in Maternal Inflammation. Int J Mol Sci. 2018;19: pubmed publisher
	Vielle N, Zumkehr B, GarcÃa NicolÃ¡s O, Blank F, Stojanov M, Musso D, et al. Silent infection of human dendritic cells by African and Asian strains of Zika virus. Sci Rep. 2018;8:5440 pubmed publisher
	Xu M, Pu Y, Han D, Shi Y, Cao X, Liang H, et al. Dendritic Cells but Not Macrophages Sense Tumor Mitochondrial DNA for Cross-priming through Signal Regulatory Protein ? Signaling. Immunity. 2017;47:363-373.e5 pubmed publisher
	Al Barwani F, Young S, Baird M, Larsen D, Ward V. Mannosylation of virus-like particles enhances internalization by antigen presenting cells. PLoS ONE. 2014;9:e104523 pubmed publisher

product information

Antigen :

CD11c

Apps. Abbrev. :

Flow Cytometry

Cat # :

301605

Clone :

3.9

Item :

PE anti-human CD11c

Isotype :

Mouse IgG1, κ

Other Names :

Integrin αX subunit, CR4, p150, ITGAX

Size :

25 tests

Price (USD) :

83 USD

Reactivity :

Human, Cynomolgus, Rhesus

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

Application Notes :

Clone 3.9 preferentially binds the activated form of CD11c, is specific for the I domain of CD11c, and is able to partially block the binding of CD11c and ICAM-4. 3.9 binding is divalent cation dependent 12 . While analyzing blood, it is best to use heparin as the anti-coagulant and not EDTA. Since the ability of clone 3.9 to bind to its target is divalent cation dependent, the usage of EDTA as an anti-coagulant may be detrimental to staining due to its chelating properties. Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections 4 , and functional assays 5,6 . The LEAF purified antibody (Endotoxin 0.1 EU/ug, Azide-Free, 0.2 um filtered) is recommended for functional assays (Cat. No. 301616). For highly sensitive assays, we recommend Ultra-LEAF purified antibody (Cat. No. 301632) with a lower endotoxin limit than standard LEAF purified antibodies (Endotoxin 0.01 EU/ug).

more info or order :

BioLegend product webpage