FITC anti-human CD11c | BioLegend 301603 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

FITC anti-human CD11c

catalog :

301603

quantity :

25 tests

price :

94 USD

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

3.9

reactivity :

human

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 13

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; 1:100; loading ...; fig 6b	Liu Y, Wang L, Song Q, Ali M, Crowe W, Kucera G, et al. Intrapleural nano-immunotherapy promotes innate and adaptive immune responses to enhance anti-PD-L1 therapy for malignant pleural effusion. Nat Nanotechnol. 2022;17:206-216 pubmed publisher
flow cytometry; human	Bendall S, Simonds E, Qiu P, Amir E, Krutzik P, Finck R, et al. Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. Science. 2011;332:687-96 pubmed publisher
	Hasaart K, Manders F, Ubels J, Verheul M, van Roosmalen M, Groenen N, et al. Human induced pluripotent stem cells display a similar mutation burden as embryonic pluripotent cells in vivo. iScience. 2022;25:103736 pubmed publisher
	Brandsma A, Bertrums E, van Roosmalen M, Hofman D, Oka R, Verheul M, et al. Mutation signatures of pediatric acute myeloid leukemia and normal blood progenitors associated with differential patient outcomes. Blood Cancer Discov. 2021;2:484-499 pubmed publisher
	Chakraborty M, Chu K, Shrestha A, Revelo X, Zhang X, Gold M, et al. Mechanical Stiffness Controls Dendritic Cell Metabolism and Function. Cell Rep. 2021;34:108609 pubmed publisher
	Marjanovic N, Hofree M, Chan J, Canner D, Wu K, Trakala M, et al. Emergence of a High-Plasticity Cell State during Lung Cancer Evolution. Cancer Cell. 2020;38:229-246.e13 pubmed publisher
	Danzer H, Glaesner J, Baerenwaldt A, Reitinger C, Lux A, Heger L, et al. Human Fcγ-receptor IIb modulates pathogen-specific versus self-reactive antibody responses in lyme arthritis. elife. 2020;9: pubmed publisher
	Matsuyama H, Isshiki T, Chiba A, Yamaguchi T, Murayama G, Akasaka Y, et al. Activation of mucosal-associated invariant T cells in the lungs of sarcoidosis patients. Sci Rep. 2019;9:13181 pubmed publisher
	Osorio F, Rosendahl Huber A, Oka R, Verheul M, Patel S, Hasaart K, et al. Somatic Mutations Reveal Lineage Relationships and Age-Related Mutagenesis in Human Hematopoiesis. Cell Rep. 2018;25:2308-2316.e4 pubmed publisher
	Buffone A, Anderson N, Hammer D. Migration against the direction of flow is LFA-1-dependent in human hematopoietic stem and progenitor cells. J Cell Sci. 2018;131: pubmed publisher
	Singh N, Herbert B, Sooranna G, Orsi N, Edey L, Dasgupta T, et al. Is myometrial inflammation a cause or a consequence of term human labour?. J Endocrinol. 2017;235:69-83 pubmed publisher
	Shen L, Chen C, Huang D, Wang R, Zhang M, Qian L, et al. Pathogenic Events in a Nonhuman Primate Model of Oral Poliovirus Infection Leading to Paralytic Poliomyelitis. J Virol. 2017;91: pubmed publisher
	Denda Nagai K, Aida S, Saba K, Suzuki K, Moriyama S, Oo Puthinan S, et al. Distribution and function of macrophage galactose-type C-type lectin 2 (MGL2/CD301b): efficient uptake and presentation of glycosylated antigens by dendritic cells. J Biol Chem. 2010;285:19193-204 pubmed publisher

product information

Antigen :

CD11c

Apps. Abbrev. :

Flow Cytometry

Cat # :

301603

Clone :

3.9

Item :

FITC anti-human CD11c

Isotype :

Mouse IgG1, κ

Other Names :

Integrin αX subunit, CR4, p150, ITGAX

Size :

25 tests

Price (USD) :

94 USD

Reactivity :

Human, Cynomolgus, Rhesus

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

FITC

Application Notes :

Clone 3.9 preferentially binds the activated form of CD11c, is specific for the I domain of CD11c, and is able to partially block the binding of CD11c and ICAM-4. 3.9 binding is divalent cation dependent 12 . While analyzing blood, it is best to use heparin as the anti-coagulant and not EDTA. Since the ability of clone 3.9 to bind to its target is divalent cation dependent, the usage of EDTA as an anti-coagulant may be detrimental to staining due to its chelating properties. Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections 4 , and functional assays 5,6 . The LEAF purified antibody (Endotoxin 0.1 EU/ug, Azide-Free, 0.2 um filtered) is recommended for functional assays (Cat. No. 301616). For highly sensitive assays, we recommend Ultra-LEAF purified antibody (Cat. No. 301632) with a lower endotoxin limit than standard LEAF purified antibodies (Endotoxin 0.01 EU/ug).

more info or order :

BioLegend product webpage