PE anti-human CD11b (activated) | BioLegend 301405 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

PE anti-human CD11b (activated)

catalog :

301405

quantity :

25 tests

price :

110 USD

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

CBRM1/5

The same clone is also sold as:

Santa Cruz Biotechnology: sc-23934 L, sc-23934
OriGene: TA320385
Invitrogen: 16-0113-82, 16-0113-025, 17-0113-41, 56-0113-42, 63-0113-42, 11-0113-42, 25-0113-41, 62-0113-41, 12-0113-42, 46-0113-42, 16-0113-38, 17-0113-42, 14-0113-81, 16-0113-050, 62-0113-42, 25-0113-42
Exbio: 12-172-C100, 1P-172-T025, 1P-172-T100, 11-172-C025, 11-172-C100

reactivity :

human

application :

flow cytometry

citations: 6

Reference
Okamura G, Ebina K, Hirao M, Chijimatsu R, Yonetani Y, Etani Y, et al. Promoting Effect of Basic Fibroblast Growth Factor in Synovial Mesenchymal Stem Cell-Based Cartilage Regeneration. Int J Mol Sci. 2020;22: pubmed publisher
Wang T, Fan C, Yao A, Xu X, Zheng G, You Y, et al. The Adaptor Protein CARD9 Protects against Colon Cancer by Restricting Mycobiota-Mediated Expansion of Myeloid-Derived Suppressor Cells. Immunity. 2018;49:504-514.e4 pubmed publisher
Alflen A, Stadler N, Aranda Lopez P, Teschner D, Theobald M, HeÃŸ G, et al. Idelalisib impairs TREM-1 mediated neutrophil inflammatory responses. Sci Rep. 2018;8:5558 pubmed publisher
Kim K, Li J, Barazia A, Tseng A, Youn S, Abbadessa G, et al. ARQ 092, an orally-available, selective AKT inhibitor, attenuates neutrophil-platelet interactions in sickle cell disease. Haematologica. 2017;102:246-259 pubmed publisher
Eleftheriou D, Ganesan V, Hong Y, Klein N, Brogan P. Endothelial injury in childhood stroke with cerebral arteriopathy: a cross-sectional study. Neurology. 2012;79:2089-96 pubmed publisher
Koleva R, Ficarro S, Radomska H, Carrasco Alfonso M, Alberta J, Webber J, et al. C/EBP? and DEK coordinately regulate myeloid differentiation. Blood. 2012;119:4878-88 pubmed publisher

product information

Antigen :

CD11b

Apps. Abbrev. :

Flow Cytometry

Cat # :

301405

Clone :

CBRM1/5

Item :

PE anti-human CD11b (activated)

Isotype :

Mouse IgG1, κ

Other Names :

Integrin αM chain, C3biR, CR3, Mac-1, Mo1, ITGAM

Size :

25 tests

Price (USD) :

110 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

Application Notes :

The CBRM1/5 antibody recognizes a subset of CD11b molecules on neutrophils and monocytes activated with chemoattractants or phorbol-esters. This antibody does not recognize "non-activated" CD11b. The epitope recognized by CBRM1/5 is contained in the I domain of the a chain. Clone CBRM1/5 binds the I domain, close to the ligand binding site. It recognizes a conformational change of the integrin 9 . Additional reported applications (for the relevant formats) include: immunoprecipitation, and blocking cell adhesion to fibrinogen and ICAM-1 1 . The CBRM1/5 antibody binds specifically to the activated form of CD11b. The LEAF™ purified antibody (Endotoxin 0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 301408).