FITC anti-human CD11b (activated) | BioLegend 301403 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

FITC anti-human CD11b (activated)

catalog :

301403

quantity :

25 tests

price :

106 USD

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

CBRM1/5

reactivity :

human

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 10

Reference
Ishiuchi N, Nakashima A, Maeda S, Miura Y, Miyasako K, Sasaki K, et al. Comparison of therapeutic effects of mesenchymal stem cells derived from superficial and deep subcutaneous adipose tissues. Stem Cell Res Ther. 2023;14:121 pubmed publisher
Li F, Gao C, Li X, Wang J, Zhao Y, Ke Y, et al. Jiyuan oridonin A induces differentiation of acute myeloid leukemia cells including leukemic stem-like cells. Front Pharmacol. 2022;13:1001552 pubmed publisher
Yao J, Li G, Cui Z, Chen P, Wang J, Hu Z, et al. The Histone Deacetylase Inhibitor I1 Induces Differentiation of Acute Leukemia Cells With MLL Gene Rearrangements via Epigenetic Modification. Front Pharmacol. 2022;13:876076 pubmed publisher
Ma X, Zhao M, Wu Z, Yao J, Zhang L, Wang J, et al. The Histone Deacetylase Inhibitor I13 Induces Differentiation of M2, M3 and M5 Subtypes of Acute Myeloid Leukemia Cells and Leukemic Stem-Like Cells. Front Oncol. 2022;12:855570 pubmed publisher
Mahajan A, Grüneboom A, Petru L, Podolska M, Kling L, Maueröder C, et al. Frontline Science: Aggregated neutrophil extracellular traps prevent inflammation on the neutrophil-rich ocular surface. J Leukoc Biol. 2019;105:1087-1098 pubmed publisher
Johnson C, O Brien X, Byrd A, Parisi V, Loosely A, Li W, et al. Integrin Cross-Talk Regulates the Human Neutrophil Response to Fungal β-Glucan in the Context of the Extracellular Matrix: A Prominent Role for VLA3 in the Antifungal Response. J Immunol. 2017;198:318-334 pubmed publisher
Yin S, Jian F, Chen Y, Chien S, Hsieh M, Hsiao P, et al. Induction of IL-25 secretion from tumour-associated fibroblasts suppresses mammary tumour metastasis. Nat Commun. 2016;7:11311 pubmed publisher
Müller Edenborn B, Frick R, Piegeler T, Schläpfer M, Roth Z graggen B, Schlicker A, et al. Volatile anaesthetics reduce neutrophil inflammatory response by interfering with CXC receptor-2 signalling. Br J Anaesth. 2015;114:143-9 pubmed publisher
Reis E, Chen H, Sfyroera G, Monk P, Köhl J, Ricklin D, et al. C5a receptor-dependent cell activation by physiological concentrations of desarginated C5a: insights from a novel label-free cellular assay. J Immunol. 2012;189:4797-805 pubmed publisher
Bryn T, Mahic M, Enserink J, Schwede F, Aandahl E, Tasken K. The cyclic AMP-Epac1-Rap1 pathway is dissociated from regulation of effector functions in monocytes but acquires immunoregulatory function in mature macrophages. J Immunol. 2006;176:7361-70 pubmed

product information

Antigen :

CD11b

Apps. Abbrev. :

Cat # :

301403

Clone :

CBRM1/5

Item :

FITC anti-human CD11b (activated)

Isotype :

Mouse IgG1, κ

Other Names :

Integrin αM chain, C3biR, CR3, Mac-1, Mo1, ITGAM

Size :

25 tests

Price (USD) :

106 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

FITC

Application Notes :

The CBRM1/5 antibody recognizes a subset of CD11b molecules on neutrophils and monocytes activated with chemoattractants or phorbol-esters. This antibody does not recognize "non-activated" CD11b. The epitope recognized by CBRM1/5 is contained in the I domain of the a chain. Clone CBRM1/5 binds the I domain, close to the ligand binding site. It recognizes a conformational change of the integrin^9.Additional reported applications (for the relevant formats) include: immunoprecipitation, and blocking cell adhesion to fibrinogen and ICAM-1^1. The CBRM1/5 antibody binds specifically to the activated form of CD11b. The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 301408).;

more info or order :

BioLegend product webpage