product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
TotalSeq™-C0161 anti-human CD11b
catalog :
301359
quantity :
10 μg
price :
369 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
ICRF44
reactivity :
human
application :
flow cytometry
more info or order :
citations: 31
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 2-5
Jakob M, Hambrecht M, Spiegel J, Kitz J, Canis M, Dressel R, et al. Pluripotent Stem Cell-Derived Mesenchymal Stem Cells Show Comparable Functionality to Their Autologous Origin. Cells. 2020;10: pubmed publisher
  • flow cytometry; human; 1:50; loading ...
Noz M, Bekkering S, Groh L, Nielen T, Lamfers E, Schlitzer A, et al. Reprogramming of bone marrow myeloid progenitor cells in patients with severe coronary artery disease. elife. 2020;9: pubmed publisher
  • flow cytometry; human; loading ...; fig 2f
Sueyoshi K, Ledderose C, Shen Y, Lee A, Shapiro N, Junger W. Lipopolysaccharide suppresses T cells by generating extracellular ATP that impairs their mitochondrial function via P2Y11 receptors. J Biol Chem. 2019;294:6283-6293 pubmed publisher
  • flow cytometry; human; loading ...; fig 1a
Kennedy J, Steain M, Slobedman B, Abendroth A. Infection and Functional Modulation of Human Monocytes and Macrophages by Varicella-Zoster Virus. J Virol. 2019;93: pubmed publisher
Xu Q, Milanez Almeida P, Martins A, Radtke A, Hoehn K, Oguz C, et al. Adaptive immune responses to SARS-CoV-2 persist in the pharyngeal lymphoid tissue of children. Nat Immunol. 2023;24:186-199 pubmed publisher
Xu C, Yang J, Kosters A, Babcock B, Qiu P, Ghosn E. Comprehensive multi-omics single-cell data integration reveals greater heterogeneity in the human immune system. iScience. 2022;25:105123 pubmed publisher
Li S, Hickey A, Shangguan S, Ehrenberg P, Geretz A, Butler L, et al. HLA-B∗46 associates with rapid HIV disease progression in Asian cohorts and prominent differences in NK cell phenotype. Cell Host Microbe. 2022;30:1173-1185.e8 pubmed publisher
Bachireddy P, Azizi E, Burdziak C, Nguyen V, Ennis C, Maurer K, et al. Mapping the evolution of T cell states during response and resistance to adoptive cellular therapy. Cell Rep. 2021;37:109992 pubmed publisher
Shangguan S, Ehrenberg P, Geretz A, Yum L, Kundu G, May K, et al. Monocyte-derived transcriptome signature indicates antibody-dependent cellular phagocytosis as a potential mechanism of vaccine-induced protection against HIV-1. elife. 2021;10: pubmed publisher
Wang E, Zhou H, Nadorp B, Cayanan G, Chen X, Yeaton A, et al. Surface antigen-guided CRISPR screens identify regulators of myeloid leukemia differentiation. Cell Stem Cell. 2021;: pubmed publisher
Morad G, Daisy C, Otu H, Libermann T, Dillon S, Moses M. Cdc42-Dependent Transfer of mir301 from Breast Cancer-Derived Extracellular Vesicles Regulates the Matrix Modulating Ability of Astrocytes at the Blood-Brain Barrier. Int J Mol Sci. 2020;21: pubmed publisher
Ryu S, Lee E, Kim D, Kim Y, Chung D, Kim J, et al. Reduction of circulating innate lymphoid cell progenitors results in impaired cytokine production by innate lymphoid cells in patients with lupus nephritis. Arthritis Res Ther. 2020;22:63 pubmed publisher
van Bergeijk P, Seneviratne U, Aparicio Prat E, Stanton R, Hasson S. SRSF1 and PTBP1 are trans-acting factors that suppress the formation of a CD33 splicing isoform linked to Alzheimer's disease risk. Mol Cell Biol. 2019;: pubmed publisher
Pohlmeyer C, Gonzalez V, Irrinki A, Ramirez R, Li L, Mulato A, et al. Identification of NK Cell Subpopulations That Differentiate HIV-Infected Subject Cohorts with Diverse Levels of Virus Control. J Virol. 2019;93: pubmed publisher
Saggu G, Okubo K, Chen Y, Vattepu R, Tsuboi N, Rosetti F, et al. Cis interaction between sialylated FcγRIIA and the αI-domain of Mac-1 limits antibody-mediated neutrophil recruitment. Nat Commun. 2018;9:5058 pubmed publisher
Buchrieser J, Oliva Martin M, Moore M, Long J, Cowley S, Perez Simon J, et al. RIPK1 is a critical modulator of both tonic and TLR-responsive inflammatory and cell death pathways in human macrophage differentiation. Cell Death Dis. 2018;9:973 pubmed publisher
Piragyte I, Clapes T, Polyzou A, Klein Geltink R, Lefkopoulos S, Yin N, et al. A metabolic interplay coordinated by HLX regulates myeloid differentiation and AML through partly overlapping pathways. Nat Commun. 2018;9:3090 pubmed publisher
Khajuria R, Munschauer M, Ulirsch J, Fiorini C, Ludwig L, McFarland S, et al. Ribosome Levels Selectively Regulate Translation and Lineage Commitment in Human Hematopoiesis. Cell. 2018;173:90-103.e19 pubmed publisher
Li N, Yang H, Wang M, Lü S, Zhang Y, Long M. Ligand-specific binding forces of LFA-1 and Mac-1 in neutrophil adhesion and crawling. Mol Biol Cell. 2018;29:408-418 pubmed publisher
Bujko A, Atlasy N, Landsverk O, Richter L, Yaqub S, Horneland R, et al. Transcriptional and functional profiling defines human small intestinal macrophage subsets. J Exp Med. 2018;215:441-458 pubmed publisher
Vargas Hernandez A, Mace E, Zimmerman O, Zerbe C, Freeman A, Rosenzweig S, et al. Ruxolitinib partially reverses functional natural killer cell deficiency in patients with signal transducer and activator of transcription 1 (STAT1) gain-of-function mutations. J Allergy Clin Immunol. 2018;141:2142-2155.e5 pubmed publisher
Wang Z, Thinn A, Zhu J. A pivotal role for a conserved bulky residue at the α1-helix of the αI integrin domain in ligand binding. J Biol Chem. 2017;292:20756-20768 pubmed publisher
Bracq L, Xie M, Lambelé M, Vu L, Matz J, Schmitt A, et al. T Cell-Macrophage Fusion Triggers Multinucleated Giant Cell Formation for HIV-1 Spreading. J Virol. 2017;91: pubmed publisher
Benedek G, Meza Romero R, Jordan K, Zhang Y, Nguyen H, Kent G, et al. MIF and D-DT are potential disease severity modifiers in male MS subjects. Proc Natl Acad Sci U S A. 2017;114:E8421-E8429 pubmed publisher
Gov L, Schneider C, Lima T, Pandori W, Lodoen M. NLRP3 and Potassium Efflux Drive Rapid IL-1β Release from Primary Human Monocytes during Toxoplasma gondii Infection. J Immunol. 2017;199:2855-2864 pubmed publisher
Wen T, Kuhl J, Putnam P, Mukkada V, Farrell M, Kaul A, et al. A flow cytometry-based diagnosis of eosinophilic esophagitis. J Allergy Clin Immunol. 2017;140:1736-1739.e3 pubmed publisher
Cobb D, Kim O, Golden Mason L, Rosen H, Hahn Y. Hepatocyte-derived exosomes promote T follicular regulatory cell expansion during hepatitis C virus infection. Hepatology. 2017;: pubmed publisher
Patel A, Zhang Y, Fullerton J, Boelen L, Rongvaux A, Maini A, et al. The fate and lifespan of human monocyte subsets in steady state and systemic inflammation. J Exp Med. 2017;214:1913-1923 pubmed publisher
Bzowska M, Nogieć A, Bania K, Zygmunt M, Zarebski M, Dobrucki J, et al. Involvement of cell surface 90 kDa heat shock protein (HSP90) in pattern recognition by human monocyte-derived macrophages. J Leukoc Biol. 2017;102:763-774 pubmed publisher
Yip B, Steeples V, Repapi E, Armstrong R, Llorian M, Roy S, et al. The U2AF1S34F mutation induces lineage-specific splicing alterations in myelodysplastic syndromes. J Clin Invest. 2017;127:2206-2221 pubmed publisher
Abud E, Ramirez R, Martinez E, Healy L, Nguyen C, Newman S, et al. iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases. Neuron. 2017;94:278-293.e9 pubmed publisher
product information
Antigen :
CD11b
Apps. Abbrev. :
PG
Cat # :
301359
Clone :
ICRF44
Item :
TotalSeq™-C0161 anti-human CD11b
Isotype :
Mouse IgG1, κ
Other Names :
Integrin αM chain, C3biR, CR3, Mac-1, Mo1, ITGAM
Size :
10 μg
Price (USD) :
369 USD
Reactivity :
Human, Cynomolgus, Rhesus
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
TOTALSEQ_C
Application Notes :
The ICRF44 antibody inhibits heterotypic adhesion of granulocytes in response to fMLP. Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections, immunofluorescence microscopy^5, stimulation of monocytes^3, blocking of heterotypic PMN aggregation^8, and blocking of granulocyte activation^12. This clone was tested in-house and does not work on formalin fixed paraffin-embedded (FFPE) tissue.The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. Nos. 301361 & 301362).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA