product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Alexa Fluor® 700 anti-human CD11b
catalog :
301356
quantity :
100 tests
price :
347 USD
clonality :
monoclonal
host :
mouse
conjugate :
AF700
clone name :
ICRF44
reactivity :
human
application :
flow cytometry
more info or order :
citations: 36
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 2-5
Jakob M, Hambrecht M, Spiegel J, Kitz J, Canis M, Dressel R, et al. Pluripotent Stem Cell-Derived Mesenchymal Stem Cells Show Comparable Functionality to Their Autologous Origin. Cells. 2020;10: pubmed publisher
  • flow cytometry; human; 1:50; loading ...
Noz M, Bekkering S, Groh L, Nielen T, Lamfers E, Schlitzer A, et al. Reprogramming of bone marrow myeloid progenitor cells in patients with severe coronary artery disease. elife. 2020;9: pubmed publisher
  • flow cytometry; human; loading ...; fig 2f
Sueyoshi K, Ledderose C, Shen Y, Lee A, Shapiro N, Junger W. Lipopolysaccharide suppresses T cells by generating extracellular ATP that impairs their mitochondrial function via P2Y11 receptors. J Biol Chem. 2019;294:6283-6293 pubmed publisher
  • flow cytometry; human; loading ...; fig 1a
Kennedy J, Steain M, Slobedman B, Abendroth A. Infection and Functional Modulation of Human Monocytes and Macrophages by Varicella-Zoster Virus. J Virol. 2019;93: pubmed publisher
Houlder E, Costain A, Nambuya I, Brown S, Koopman J, Langenberg M, et al. Pulmonary inflammation promoted by type-2 dendritic cells is a feature of human and murine schistosomiasis. Nat Commun. 2023;14:1863 pubmed publisher
Aru B, Akdeniz T, Da x11f deviren H, G xfc rel G, Yan x131 kkaya Demirel G. Testosterone Propionate Promotes Proliferation and Viability of Bone Marrow Mesenchymal Stem Cells while Preserving Their Characteristics and Inducing Their Anti-Cancer Efficacy. Balkan Med J. 2023;40:117-123 pubmed publisher
Bettini E, Lederer K, Sharpe H, Kaminski M, Jones L, Locci M. A combined fine needle aspiration and spectral flow cytometry approach to assess human germinal center responses to SARS-CoV-2 vaccination. STAR Protoc. 2022;3:101840 pubmed publisher
Lo M, Amarilla A, Lee J, Albornoz E, Modhiran N, Clark R, et al. SARS-CoV-2 triggers complement activation through interactions with heparan sulfate. Clin Transl Immunology. 2022;11:e1413 pubmed publisher
Lederer K, Bettini E, Parvathaneni K, Painter M, Agarwal D, Lundgreen K, et al. Germinal center responses to SARS-CoV-2 mRNA vaccines in healthy and immunocompromised individuals. Cell. 2022;185:1008-1024.e15 pubmed publisher
Hakki S, Robinson E, Robson M. Circulating Interleukin-6 and CD16 positive monocytes increase following angioplasty of an arteriovenous fistula. Sci Rep. 2022;12:1427 pubmed publisher
Gao R, He B, Huang Q, Wang Z, Yan M, Lam E, et al. Cancer cell immune mimicry delineates onco-immunologic modulation. iScience. 2021;24:103133 pubmed publisher
Wiesner D, Merkhofer R, Ober C, Kujoth G, Niu M, Keller N, et al. Club Cell TRPV4 Serves as a Damage Sensor Driving Lung Allergic Inflammation. Cell Host Microbe. 2020;27:614-628.e6 pubmed publisher
Zhou W, Yui M, Williams B, Yun J, Wold B, Cai L, et al. Single-Cell Analysis Reveals Regulatory Gene Expression Dynamics Leading to Lineage Commitment in Early T Cell Development. Cell Syst. 2019;9:321-337.e9 pubmed publisher
Hunegnaw R, Mushtaq Z, Enyindah Asonye G, Hoang T, Robert Guroff M. Alveolar Macrophage Dysfunction and Increased PD-1 Expression During Chronic SIV Infection of Rhesus Macaques. Front Immunol. 2019;10:1537 pubmed publisher
Ristow L, Tran V, Schwartz K, Pankratz L, Mehle A, Sauer J, et al. The Extracellular Domain of the β2 Integrin β Subunit (CD18) Is Sufficient for Escherichia coli Hemolysin and Aggregatibacter actinomycetemcomitans Leukotoxin Cytotoxic Activity. MBio. 2019;10: pubmed publisher
van Bergeijk P, Seneviratne U, Aparicio Prat E, Stanton R, Hasson S. SRSF1 and PTBP1 are trans-acting factors that suppress the formation of a CD33 splicing isoform linked to Alzheimer's disease risk. Mol Cell Biol. 2019;: pubmed publisher
Pohlmeyer C, Gonzalez V, Irrinki A, Ramirez R, Li L, Mulato A, et al. Identification of NK Cell Subpopulations That Differentiate HIV-Infected Subject Cohorts with Diverse Levels of Virus Control. J Virol. 2019;93: pubmed publisher
Richardson J, Armbruster N, Günter M, Henes J, Autenrieth S. Staphylococcus aureus PSM Peptides Modulate Human Monocyte-Derived Dendritic Cells to Prime Regulatory T Cells. Front Immunol. 2018;9:2603 pubmed publisher
Saggu G, Okubo K, Chen Y, Vattepu R, Tsuboi N, Rosetti F, et al. Cis interaction between sialylated FcγRIIA and the αI-domain of Mac-1 limits antibody-mediated neutrophil recruitment. Nat Commun. 2018;9:5058 pubmed publisher
Buchrieser J, Oliva Martin M, Moore M, Long J, Cowley S, Perez Simon J, et al. RIPK1 is a critical modulator of both tonic and TLR-responsive inflammatory and cell death pathways in human macrophage differentiation. Cell Death Dis. 2018;9:973 pubmed publisher
Piragyte I, Clapes T, Polyzou A, Klein Geltink R, Lefkopoulos S, Yin N, et al. A metabolic interplay coordinated by HLX regulates myeloid differentiation and AML through partly overlapping pathways. Nat Commun. 2018;9:3090 pubmed publisher
Tseng A, Kim K, Li J, Cho J. Myeloperoxidase Negatively Regulates Neutrophil-Endothelial Cell Interactions by Impairing αMβ2 Integrin Function in Sterile Inflammation. Front Med (Lausanne). 2018;5:134 pubmed publisher
Khajuria R, Munschauer M, Ulirsch J, Fiorini C, Ludwig L, McFarland S, et al. Ribosome Levels Selectively Regulate Translation and Lineage Commitment in Human Hematopoiesis. Cell. 2018;173:90-103.e19 pubmed publisher
Li N, Yang H, Wang M, Lü S, Zhang Y, Long M. Ligand-specific binding forces of LFA-1 and Mac-1 in neutrophil adhesion and crawling. Mol Biol Cell. 2018;29:408-418 pubmed publisher
Bujko A, Atlasy N, Landsverk O, Richter L, Yaqub S, Horneland R, et al. Transcriptional and functional profiling defines human small intestinal macrophage subsets. J Exp Med. 2018;215:441-458 pubmed publisher
Vargas Hernandez A, Mace E, Zimmerman O, Zerbe C, Freeman A, Rosenzweig S, et al. Ruxolitinib partially reverses functional natural killer cell deficiency in patients with signal transducer and activator of transcription 1 (STAT1) gain-of-function mutations. J Allergy Clin Immunol. 2018;141:2142-2155.e5 pubmed publisher
Wang Z, Thinn A, Zhu J. A pivotal role for a conserved bulky residue at the α1-helix of the αI integrin domain in ligand binding. J Biol Chem. 2017;292:20756-20768 pubmed publisher
Bracq L, Xie M, Lambelé M, Vu L, Matz J, Schmitt A, et al. T Cell-Macrophage Fusion Triggers Multinucleated Giant Cell Formation for HIV-1 Spreading. J Virol. 2017;91: pubmed publisher
Benedek G, Meza Romero R, Jordan K, Zhang Y, Nguyen H, Kent G, et al. MIF and D-DT are potential disease severity modifiers in male MS subjects. Proc Natl Acad Sci U S A. 2017;114:E8421-E8429 pubmed publisher
Gov L, Schneider C, Lima T, Pandori W, Lodoen M. NLRP3 and Potassium Efflux Drive Rapid IL-1β Release from Primary Human Monocytes during Toxoplasma gondii Infection. J Immunol. 2017;199:2855-2864 pubmed publisher
Wen T, Kuhl J, Putnam P, Mukkada V, Farrell M, Kaul A, et al. A flow cytometry-based diagnosis of eosinophilic esophagitis. J Allergy Clin Immunol. 2017;140:1736-1739.e3 pubmed publisher
Cobb D, Kim O, Golden Mason L, Rosen H, Hahn Y. Hepatocyte-derived exosomes promote T follicular regulatory cell expansion during hepatitis C virus infection. Hepatology. 2017;: pubmed publisher
Patel A, Zhang Y, Fullerton J, Boelen L, Rongvaux A, Maini A, et al. The fate and lifespan of human monocyte subsets in steady state and systemic inflammation. J Exp Med. 2017;214:1913-1923 pubmed publisher
Bzowska M, Nogieć A, Bania K, Zygmunt M, Zarebski M, Dobrucki J, et al. Involvement of cell surface 90 kDa heat shock protein (HSP90) in pattern recognition by human monocyte-derived macrophages. J Leukoc Biol. 2017;102:763-774 pubmed publisher
Yip B, Steeples V, Repapi E, Armstrong R, Llorian M, Roy S, et al. The U2AF1S34F mutation induces lineage-specific splicing alterations in myelodysplastic syndromes. J Clin Invest. 2017;127:2206-2221 pubmed publisher
Abud E, Ramirez R, Martinez E, Healy L, Nguyen C, Newman S, et al. iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases. Neuron. 2017;94:278-293.e9 pubmed publisher
product information
Antigen :
CD11b
Apps. Abbrev. :
FC
Cat # :
301356
Clone :
ICRF44
Item :
Alexa Fluor® 700 anti-human CD11b
Isotype :
Mouse IgG1, κ
Other Names :
Integrin αM chain, C3biR, CR3, Mac-1, Mo1, ITGAM
Size :
100 tests
Price (USD) :
347 USD
Reactivity :
Human, Cynomolgus, Rhesus
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
A700
Application Notes :
The ICRF44 antibody inhibits heterotypic adhesion of granulocytes in response to fMLP. Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections, immunofluorescence microscopy^5, stimulation of monocytes^3, blocking of heterotypic PMN aggregation^8, and blocking of granulocyte activation^12. This clone was tested in-house and does not work on formalin fixed paraffin-embedded (FFPE) tissue.The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. Nos. 301361 & 301362).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA