product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
FITC anti-human CD11b
catalog :
301330
quantity :
100 tests
price :
105 USD
clonality :
monoclonal
host :
mouse
conjugate :
FITC
clone name :
ICRF44
reactivity :
human
application :
flow cytometry
more info or order :
citations: 44
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human
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Reynolds M, Hong H, Michmerhuizen B, Lawrence A, Zhang L, Knight J, et al. Cardiolipin coordinates inflammatory metabolic reprogramming through regulation of Complex II disassembly and degradation. Sci Adv. 2023;9:eade8701 pubmed publisher
Voit R, Tao L, Yu F, Cato L, Cohen B, Fleming T, et al. A genetic disorder reveals a hematopoietic stem cell regulatory network co-opted in leukemia. Nat Immunol. 2023;24:69-83 pubmed publisher
Bhattacharya S, Basu S, Sheng E, Murphy C, Wei J, Kersh A, et al. Identification of a neutrophil-specific PIK3R1 mutation facilitates targeted treatment in a patient with Sweet syndrome. J Clin Invest. 2023;133: pubmed publisher
Xu Q, Liu H, Qile M, Wuren T. Dynamic changes in myeloid-derived suppressor cells during the menstrual cycle: A pilot study. Front Med (Lausanne). 2022;9:940554 pubmed publisher
Jiang L, Xu C, Zhao Y, Huang Q, Yuan W, Wu Y, et al. Papain ameliorates monocyte-platelet aggregate formation-mediated inflammatory responses in monocytes by upregulating miRNA-146a transcription. PLoS ONE. 2022;17:e0278059 pubmed publisher
Zhang Y, Wang X, Xu C, Liu N, Zhang L, Zhang Y, et al. A direct comparison between AML1-ETO and ETO2-GLIS2 leukemia fusion proteins reveals context-dependent binding and regulation of target genes and opposite functions in cell differentiation. Front Cell Dev Biol. 2022;10:992714 pubmed publisher
Zhao M, Duan Y, Wang J, Liu Y, Zhao Y, Wang H, et al. Histone Deacetylase Inhibitor I3 Induces the Differentiation of Acute Myeloid Leukemia Cells with t (8; 21) or MLL Gene Translocation and Leukemic Stem-Like Cells. J Oncol. 2022;2022:3345536 pubmed publisher
Yan K, Zhang J, Yin W, Harding J, Ma F, Wu D, et al. Transcriptomic heterogeneity of cultured ADSCs corresponds to embolic risk in the host. iScience. 2022;25:104822 pubmed publisher
Wang H, Huang Q, Zhang Z, Ji J, Sun T, Wang D. Transient post-operative overexpression of CXCR2 on monocytes of traumatic brain injury patients drives monocyte chemotaxis toward cerebrospinal fluid and enhances monocyte-mediated immunogenic cell death of neurons in vitro. J Neuroinflammation. 2022;19:171 pubmed publisher
Takano T, Morikawa M, Adachi Y, Kabasawa K, Sax N, Moriyama S, et al. Distinct immune cell dynamics correlate with the immunogenicity and reactogenicity of SARS-CoV-2 mRNA vaccine. Cell Rep Med. 2022;3:100631 pubmed publisher
Hou Y, Jing J, Luo Y, Xu F, Xie W, Ma L, et al. A Versatile, Incubator-Compatible, Monolithic GaN Photonic Chipscope for Label-Free Monitoring of Live Cell Activities. Adv Sci (Weinh). 2022;9:e2200910 pubmed publisher
Li Y, Zhou Y, Kim Y, Zhu Y, Ma F, Yu J, et al. Development of allogeneic HSC-engineered iNKT cells for off-the-shelf cancer immunotherapy. Cell Rep Med. 2021;2:100449 pubmed publisher
Tu J, Li W, Yang S, Yang P, Yan Q, Wang S, et al. Single-Cell Transcriptome Profiling Reveals Multicellular Ecosystem of Nucleus Pulposus during Degeneration Progression. Adv Sci (Weinh). 2021;:e2103631 pubmed publisher
Qu J, Sun Z, Peng C, Li D, Yan W, Xu Z, et al. C. tropicalis promotes chemotherapy resistance in colon cancer through increasing lactate production to regulate the mismatch repair system. Int J Biol Sci. 2021;17:2756-2769 pubmed publisher
Bodnar B, Zhang Y, Liu J, Lin Y, Wang P, Wei Z, et al. Novel Scalable and Simplified System to Generate Microglia-Containing Cerebral Organoids From Human Induced Pluripotent Stem Cells. Front Cell Neurosci. 2021;15:682272 pubmed publisher
Medapati M, Singh N, Bhagirath A, Duan K, Triggs Raine B, Batista E, et al. Bitter taste receptor T2R14 detects quorum sensing molecules from cariogenic Streptococcus mutans and mediates innate immune responses in gingival epithelial cells. FASEB J. 2021;35:e21375 pubmed publisher
Fatemi A, Alipour R, Khanahmad H, Alsahebfosul F, Andalib A, Pourazar A. The impact of neutrophil extracellular trap from patients with systemic lupus erythematosus on the viability, CD11b expression and oxidative burst of healthy neutrophils. BMC Immunol. 2021;22:12 pubmed publisher
Takano T, Matsumura T, Adachi Y, Terahara K, Moriyama S, Onodera T, et al. Myeloid cell dynamics correlating with clinical outcomes of severe COVID-19 in Japan. Int Immunol. 2021;33:241-247 pubmed publisher
Mpakou V, Spathis A, Bouhla A, Mpazani E, Papageorgiou S, Gkontopoulos K, et al. Synergistic inhibitory effects of low-dose decitabine in combination with bortezomib in the AML cell line Kasumi-1. Exp Ther Med. 2021;21:195 pubmed publisher
Li K, Wang F, Yang Z, Zhang T, Yuan Y, Zhao C, et al. TRIB3 promotes MYC-associated lymphoma development through suppression of UBE3B-mediated MYC degradation. Nat Commun. 2020;11:6316 pubmed publisher
Fan Z, Mikulski Z, McArdle S, Sundd P, Ley K. Super-STORM: Molecular Modeling to Achieve Single-molecule Localization with STORM Microscopy. STAR Protoc. 2020;1:100012 pubmed publisher
Blank A, Kremenetskaia I, Urbantat R, Acker G, Turkowski K, Radke J, et al. Microglia/macrophages express alternative proangiogenic factors depending on granulocyte content in human glioblastoma. J Pathol. 2021;253:160-173 pubmed publisher
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He Z, Li W, Zheng T, Liu D, Zhao S. Human umbilical cord mesenchymal stem cells-derived exosomes deliver microRNA-375 to downregulate ENAH and thus retard esophageal squamous cell carcinoma progression. J Exp Clin Cancer Res. 2020;39:140 pubmed publisher
Friebel E, Kapolou K, Unger S, Núñez N, Utz S, Rushing E, et al. Single-Cell Mapping of Human Brain Cancer Reveals Tumor-Specific Instruction of Tissue-Invading Leukocytes. Cell. 2020;181:1626-1642.e20 pubmed publisher
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Lin F, Yin H, Li X, Zhu G, He W, Gou X. Bladder cancer cell‑secreted exosomal miR‑21 activates the PI3K/AKT pathway in macrophages to promote cancer progression. Int J Oncol. 2020;56:151-164 pubmed publisher
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product information
Antigen :
CD11b
Apps. Abbrev. :
FC
Cat # :
301330
Clone :
ICRF44
Item :
FITC anti-human CD11b
Isotype :
Mouse IgG1, κ
Other Names :
Integrin αM chain, C3biR, CR3, Mac-1, Mo1, ITGAM
Size :
100 tests
Price (USD) :
105 USD
Reactivity :
Human, Cynomolgus, Rhesus
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
FITC
Application Notes :
The ICRF44 antibody inhibits heterotypic adhesion of granulocytes in response to fMLP. Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections, immunofluorescence microscopy^5, stimulation of monocytes^3, blocking of heterotypic PMN aggregation^8, and blocking of granulocyte activation^12. This clone was tested in-house and does not work on formalin fixed paraffin-embedded (FFPE) tissue.The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. Nos. 301361 & 301362).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA