product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Pacific Blue™ anti-human CD11b
catalog :
301315
quantity :
100 μg
price :
248 USD
clonality :
monoclonal
host :
mouse
conjugate :
Pacific Blue
clone name :
ICRF44
reactivity :
human, chimpanzee
application :
flow cytometry
more info or order :
citations: 14
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 2-5
Jakob M, Hambrecht M, Spiegel J, Kitz J, Canis M, Dressel R, et al. Pluripotent Stem Cell-Derived Mesenchymal Stem Cells Show Comparable Functionality to Their Autologous Origin. Cells. 2020;10: pubmed publisher
  • flow cytometry; human; fig s1c
Khajuria R, Munschauer M, Ulirsch J, Fiorini C, Ludwig L, McFarland S, et al. Ribosome Levels Selectively Regulate Translation and Lineage Commitment in Human Hematopoiesis. Cell. 2018;173:90-103.e19 pubmed publisher
  • flow cytometry; human
Bendall S, Simonds E, Qiu P, Amir E, Krutzik P, Finck R, et al. Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. Science. 2011;332:687-96 pubmed publisher
Shukla S, Ying W, Gray F, Yao Y, Simes M, Zhao Q, et al. Small-molecule inhibitors targeting Polycomb repressive complex 1 RING domain. Nat Chem Biol. 2021;17:784-793 pubmed publisher
Wang F, Jia W, Fan M, Shao X, Li Z, Liu Y, et al. Single-cell Immune Landscape of Human Recurrent Miscarriage. Genomics Proteomics Bioinformatics. 2021;19:208-222 pubmed publisher
Ma L, Gonzàlez Juncà A, Zheng Y, Ouyang H, Illa Bochaca I, Horst K, et al. Inflammation Mediates the Development of Aggressive Breast Cancer Following Radiotherapy. Clin Cancer Res. 2021;27:1778-1791 pubmed publisher
Reed J, Preston Hurlburt P, Philbrick W, Betancur G, Korah M, LUCAS C, et al. The receptor for advanced glycation endproducts (RAGE) modulates T cell signaling. PLoS ONE. 2020;15:e0236921 pubmed publisher
Serr I, Fürst R, Achenbach P, Scherm M, Gökmen F, Haupt F, et al. Type 1 diabetes vaccine candidates promote human Foxp3(+)Treg induction in humanized mice. Nat Commun. 2016;7:10991 pubmed publisher
Larsson K, Kock A, Idborg H, Arsenian Henriksson M, Martinsson T, Johnsen J, et al. COX/mPGES-1/PGE2 pathway depicts an inflammatory-dependent high-risk neuroblastoma subset. Proc Natl Acad Sci U S A. 2015;112:8070-5 pubmed publisher
Headland S, Jones H, D Sa A, Perretti M, Norling L. Cutting-edge analysis of extracellular microparticles using ImageStream(X) imaging flow cytometry. Sci Rep. 2014;4:5237 pubmed publisher
Wen T, Mingler M, Wahl B, Khorki M, Pabst O, Zimmermann N, et al. Carbonic anhydrase IV is expressed on IL-5-activated murine eosinophils. J Immunol. 2014;192:5481-9 pubmed publisher
Cash J, Bena S, Headland S, McArthur S, Brancaleone V, Perretti M. Chemerin15 inhibits neutrophil-mediated vascular inflammation and myocardial ischemia-reperfusion injury through ChemR23. EMBO Rep. 2013;14:999-1007 pubmed publisher
Thurlow L, Thomas V, Narayanan S, Olson S, Fleming S, Hancock L. Gelatinase contributes to the pathogenesis of endocarditis caused by Enterococcus faecalis. Infect Immun. 2010;78:4936-43 pubmed publisher
Charles N, Hardwick D, Daugas E, Illei G, Rivera J. Basophils and the T helper 2 environment can promote the development of lupus nephritis. Nat Med. 2010;16:701-7 pubmed publisher
product information
Antigen :
CD11b
Apps. Abbrev. :
Flow Cytometry
Cat # :
301315
Clone :
ICRF44
Item :
Pacific Blue™ anti-human CD11b
Isotype :
Mouse IgG1, κ
Other Names :
Integrin αM chain, C3biR, CR3, Mac-1, Mo1, ITGAM
Size :
100 μg
Price (USD) :
248 USD
Reactivity :
Human, African Green, Baboon, Chimpanzee, Common Marmoset, Cynomolgus, Rhesus, Swine (Pig, Porcine)
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PB
Application Notes :
The ICRF44 antibody inhibits heterotypic adhesion of granulocytes in response to fMLP. Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections, immunofluorescence microscopy 5 , stimulation of monocytes 3 , blocking of heterotypic PMN aggregation 8 , and blocking of granulocyte activation 12 . This clone was tested in-house and does not work on formalin fixed paraffin-embedded (FFPE) tissue. The Ultra-LEAF purified antibody (Endotoxin 0.01 EU/ug, Azide-Free, 0.2 um filtered) is recommended for functional assays (Cat. Nos. 301361 301362).
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA