APC/Cyanine7 anti-human CD11a | BioLegend 301235 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

APC/Cyanine7 anti-human CD11a

catalog :

301235

quantity :

25 tests

price :

153 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

HI111

reactivity :

human

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 2

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig s1	Matsumoto K, Kurasawa T, Yoshimoto K, Suzuki K, Takeuchi T. Identification of neutrophil β2-integrin LFA-1 as a potential mechanistic biomarker in ANCA-associated vasculitis via microarray and validation analyses. Arthritis Res Ther. 2021;23:136 pubmed publisher
	Reed J, Preston Hurlburt P, Philbrick W, Betancur G, Korah M, LUCAS C, et al. The receptor for advanced glycation endproducts (RAGE) modulates T cell signaling. PLoS ONE. 2020;15:e0236921 pubmed publisher

product information

Antigen :

CD11a

Apps. Abbrev. :

Cat # :

301235

Clone :

HI111

Item :

APC/Cyanine7 anti-human CD11a

Isotype :

Mouse IgG1, κ

Other Names :

LFA-1α chain, Integrin αL subunit, αL Integrin, ITGAL

Size :

25 tests

Price (USD) :

153 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

APC_CYANINE7

Application Notes :

Clone HI111 epitope maps to the top region of the I domain that is close to the putative ligand-binding site surrounding the MIDAS (metal ion-dependent adhesion site). HI111 is specific for the closed confirmation of the integrin^8. Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen sections, Western blotting^2, and blocking of cell-cell interaction and inhibition the binding of ICAM-1^4. This clone was tested in-house and does not work on formalin fixed paraffin-embedded (FFPE) tissue. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 301233 & 301234).;

more info or order :

BioLegend product webpage